ES361699A1 - Procedimiento para la preparacion de alcoholes 2-amino-me- tilbencilo alfa-sustituidos. - Google Patents

Procedimiento para la preparacion de alcoholes 2-amino-me- tilbencilo alfa-sustituidos.

Info

Publication number: ES361699A1
Authority: ES; Spain
Prior art keywords: signifies; alkyl; compounds; benzyl; chlorophenyl
Prior art date: 1967-12-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES361699A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CH Boehringer Sohn AG and Co KG

Original Assignee

CH Boehringer Sohn AG and Co KG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1967-12-22

Filing date

1968-12-20

Publication date

1970-12-16

1968-12-20 Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG

1970-12-16 Publication of ES361699A1 publication Critical patent/ES361699A1/es

Status Expired legal-status Critical Current

Links

WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical class OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 8
125000000217 alkyl group Chemical group 0.000 abstract 5
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 5
-1 R 4 signifies H Chemical group 0.000 abstract 3
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
229910052736 halogen Inorganic materials 0.000 abstract 3
150000002367 halogens Chemical class 0.000 abstract 3
WNZQDUSMALZDQF-UHFFFAOYSA-N 2-benzofuran-1(3H)-one Chemical compound C1=CC=C2C(=O)OCC2=C1 WNZQDUSMALZDQF-UHFFFAOYSA-N 0.000 abstract 2
125000002252 acyl group Chemical group 0.000 abstract 2
125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 abstract 2
MAXSBWBJHLAUSF-UHFFFAOYSA-N 3-(4-chlorophenyl)-2,3-dimethylisoindol-1-one Chemical compound CN1C(=O)C2=CC=CC=C2C1(C)C1=CC=C(Cl)C=C1 MAXSBWBJHLAUSF-UHFFFAOYSA-N 0.000 abstract 1
229910010082 LiAlH Inorganic materials 0.000 abstract 1
238000000297 Sandmeyer reaction Methods 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000004945 acylaminoalkyl group Chemical group 0.000 abstract 1
230000010933 acylation Effects 0.000 abstract 1
238000005917 acylation reaction Methods 0.000 abstract 1
125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
230000029936 alkylation Effects 0.000 abstract 1
238000005804 alkylation reaction Methods 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000004103 aminoalkyl group Chemical group 0.000 abstract 1
230000036528 appetite Effects 0.000 abstract 1
235000019789 appetite Nutrition 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000000596 cyclohexenyl group Chemical group C1(=CCCCC1)* 0.000 abstract 1
125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
230000032050 esterification Effects 0.000 abstract 1
238000005886 esterification reaction Methods 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
238000006266 etherification reaction Methods 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical compound C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 abstract 1
239000008141 laxative Substances 0.000 abstract 1
230000002475 laxative effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
101150009274 nhr-1 gene Proteins 0.000 abstract 1
150000002825 nitriles Chemical class 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
238000007142 ring opening reaction Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000010561 standard procedure Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES361699A 1967-12-22 1968-12-20 Procedimiento para la preparacion de alcoholes 2-amino-me- tilbencilo alfa-sustituidos. Expired ES361699A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE1643265		1967-12-22

Publications (1)

Publication Number	Publication Date
ES361699A1 true ES361699A1 (es)	1970-12-16

Family

ID=5684276

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES361699A Expired ES361699A1 (es)	1967-12-22	1968-12-20	Procedimiento para la preparacion de alcoholes 2-amino-me- tilbencilo alfa-sustituidos.
ES380256A Expired ES380256A1 (es)	1967-12-22	1970-06-01	Procedimiento para la preparacion de alcoholes 2-amino-me- til-bencilo alfa sustituidos.
ES380255A Expired ES380255A1 (es)	1967-12-22	1970-06-01	Procedimiento para la preparacion de alcoholes 2-amino-me- til-bencilo alfa-sustituidos.

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
ES380256A Expired ES380256A1 (es)	1967-12-22	1970-06-01	Procedimiento para la preparacion de alcoholes 2-amino-me- til-bencilo alfa sustituidos.
ES380255A Expired ES380255A1 (es)	1967-12-22	1970-06-01	Procedimiento para la preparacion de alcoholes 2-amino-me- til-bencilo alfa-sustituidos.

Country Status (10)

Country	Link
AT (3)	AT295502B (fr)
BE (1)	BE725839A (fr)
CH (2)	CH530368A (fr)
DE (1)	DE1643265C3 (fr)
DK (1)	DK131670C (fr)
ES (3)	ES361699A1 (fr)
FR (2)	FR1600541A (fr)
GB (1)	GB1249148A (fr)
NL (1)	NL160804C (fr)
SE (1)	SE360651B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10021246A1 (de) *	2000-04-25	2001-10-31	Schering Ag	Substituierte Benzoesäureamide und deren Verwendung als Arzneimittel

1967
- 1967-12-22 DE DE1967B0095987 patent/DE1643265C3/de not_active Expired
1968
- 1968-12-19 CH CH1891068A patent/CH530368A/de not_active IP Right Cessation
- 1968-12-19 CH CH567071A patent/CH536807A/de not_active IP Right Cessation
- 1968-12-20 SE SE1758468A patent/SE360651B/xx unknown
- 1968-12-20 AT AT1160470A patent/AT295502B/de not_active IP Right Cessation
- 1968-12-20 ES ES361699A patent/ES361699A1/es not_active Expired
- 1968-12-20 BE BE725839D patent/BE725839A/xx not_active IP Right Cessation
- 1968-12-20 AT AT1160570A patent/AT295503B/de not_active IP Right Cessation
- 1968-12-20 NL NL6818378A patent/NL160804C/xx not_active IP Right Cessation
- 1968-12-20 DK DK628168A patent/DK131670C/da not_active IP Right Cessation
- 1968-12-20 AT AT1241968A patent/AT294045B/de not_active IP Right Cessation
- 1968-12-20 FR FR1600541D patent/FR1600541A/fr not_active Expired
- 1968-12-23 GB GB6112068A patent/GB1249148A/en not_active Expired
1969
- 1969-03-20 FR FR183296A patent/FR8329M/fr not_active Expired
1970
- 1970-06-01 ES ES380256A patent/ES380256A1/es not_active Expired
- 1970-06-01 ES ES380255A patent/ES380255A1/es not_active Expired

Also Published As

Publication number	Publication date
DE1643265B2 (de)	1977-12-15
CH536807A (de)	1973-06-29
AT295503B (de)	1972-01-10
DE1643265C3 (de)	1978-08-31
AT295502B (de)	1972-01-10
DE1643265A1 (de)	1971-07-29
ES380255A1 (es)	1972-09-01
NL160804B (nl)	1979-07-16
FR1600541A (fr)	1970-07-27
FR8329M (fr)	1970-12-07
AT294045B (de)	1971-11-10
GB1249148A (en)	1971-10-06
SE360651B (fr)	1973-10-01
NL6818378A (fr)	1969-06-24
BE725839A (fr)	1969-06-20
NL160804C (nl)	1979-12-17
ES380256A1 (es)	1972-09-01
DK131670B (da)	1975-08-18
CH530368A (de)	1972-11-15
DK131670C (da)	1976-01-19

Publication	Publication Date	Title
ES408226A1 (es)	1976-02-01	Procedimiento para preparar acidos quinazolin-4-il?indol-3-ilaceticos.
NO872686L (no)	1987-06-26	Nye farmakologiske forbindelser.
NO881616L (no)	1988-10-31	Middel til innsekts- og middbekjempelse.
ES461399A1 (es)	1978-05-16	Procedimiento para preparar esteres de epinina con acidos carboxilicos de cadena ramificada.
ES416877A1 (es)	1976-02-16	Procedimiento para la preparacion del nuevo compuesto acido(1-(para-clorobenzoil) - 5 - metoxi - 2 - metil - 3 - indol)acetoxi-acetico.
GB1086192A (en)	1967-10-04	Phenylcyclopropane derivatives
KR950003262A (ko)	1995-02-16	1- 아릴옥시-3- 알킬아미노-2-프로판올 니트레이트 에스테르, 이의 용도 및 상응하는 약제학적 조성물
ES361699A1 (es)	1970-12-16	Procedimiento para la preparacion de alcoholes 2-amino-me- tilbencilo alfa-sustituidos.
GB1187348A (en)	1970-04-08	New Amidoximes and process for the preparation thereof
GB1174673A (en)	1969-12-17	Substituted Phenyl Acetamides, a Process for their Manufacture and Preparations Containing Them
GB1346554A (en)	1974-02-13	Derivatives of thienyl-3,-acetic acid and processes for their preparation
GB1293702A (en)	1972-10-25	4,5-diphenyloxazole derivatives
ES343995A1 (es)	1968-12-16	Procedimiento para la produccion de 4,5-difenil-oxazoles 2-amino-sustituidos de efectos antiinflamatorios.
GB1324423A (en)	1973-07-25	Salicylamide derivatives
GB1304622A (fr)	1973-01-24
GB1084440A (en)	1967-09-20	Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof
FR2395250A1 (fr)	1979-01-19	Derives des acides amino- du guanidino-phenylpropioniques
GB1444870A (en)	1976-08-04	Pyrazoline derivatives
ES364718A1 (es)	1970-12-16	Procedimiento para la preparacion de nuevos derivados de bencensulfonamida.
GB1109959A (en)	1968-04-18	Dioxolan, oxathiolan and dithiolan derivatives
GB1157912A (en)	1969-07-09	Derivatives of Vernamycin B
GB1070309A (en)	1967-06-01	4-aminoquinoline derivatives
GB1269400A (en)	1972-04-06	alpha-IMIDOACRYLATES HAVING INSECTICIDAL ACTIVITY
GB1247783A (en)	1971-09-29	Production of indole acetaldehydes
GB1223548A (en)	1971-02-24	Fluorene-derived sulphones