ES362130A1 - Novel radioactive compounds derived from difluoresceinylmercury and labelled with radioactive mercury isotopes - Google Patents
Novel radioactive compounds derived from difluoresceinylmercury and labelled with radioactive mercury isotopesInfo
- Publication number
- ES362130A1 ES362130A1 ES362130A ES362130A ES362130A1 ES 362130 A1 ES362130 A1 ES 362130A1 ES 362130 A ES362130 A ES 362130A ES 362130 A ES362130 A ES 362130A ES 362130 A1 ES362130 A1 ES 362130A1
- Authority
- ES
- Spain
- Prior art keywords
- mercury
- labelled
- bis
- radioactive
- difluoresceinylmercury
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 title abstract 9
- 229910052753 mercury Inorganic materials 0.000 title abstract 9
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000002285 radioactive effect Effects 0.000 title abstract 4
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical class O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 abstract 1
- 229940100892 mercury compound Drugs 0.000 abstract 1
- 150000002731 mercury compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Compounds of the general formula wherein R is hydrogen or a halogen R1, R2, R3, R4 and R5 are hydrogen, a halogen, an alkyl residue having 1 to 5 carbon atoms or a XHggroup, X being an anion the compounds being labelled with radio-active mercury, are prepared by reacting a radio-active ionic mercury compound and an excess of the fluorescein derivative. Specified compounds prepared by the process of the invention are: difluoresceinyl mercury bis - (21,71 - dibromofluoresceinyl) mercury bis - (41,51 - dibromofluoresceinyl) mercury bis - (41,51 - diiodofluoresceinyl) mercury bis - (21,71 - diiodofluoresceinyl) mercury bis - (tetrabromofluoresceinyl) mercury and bis - (tetraiodofluoresceinyl) mercury. Each of these may be labelled with 203Hg or 197Hg.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS45668 | 1968-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES362130A1 true ES362130A1 (en) | 1971-05-01 |
Family
ID=5336652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES362130A Expired ES362130A1 (en) | 1968-01-19 | 1969-01-04 | Novel radioactive compounds derived from difluoresceinylmercury and labelled with radioactive mercury isotopes |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE725326A (en) |
| BR (1) | BR6805051D0 (en) |
| CH (1) | CH510054A (en) |
| DE (1) | DE1814671C3 (en) |
| ES (1) | ES362130A1 (en) |
| FR (1) | FR1601504A (en) |
| GB (1) | GB1220500A (en) |
| NL (1) | NL6900831A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3580190B1 (en) * | 2017-02-08 | 2021-08-04 | Helmholtz-Zentrum Dresden - Rossendorf e.V. | In vivo stable hg-197(m) compounds, method for the production thereof and use thereof in nuclear medical diagnostics and endoradionuclide therapy (theranostics) |
-
1968
- 1968-12-04 CH CH1810368A patent/CH510054A/en not_active IP Right Cessation
- 1968-12-06 GB GB5793468A patent/GB1220500A/en not_active Expired
- 1968-12-12 BE BE725326D patent/BE725326A/xx unknown
- 1968-12-14 DE DE19681814671 patent/DE1814671C3/en not_active Expired
- 1968-12-20 BR BR20505168A patent/BR6805051D0/en unknown
- 1968-12-24 FR FR1601504D patent/FR1601504A/fr not_active Expired
-
1969
- 1969-01-04 ES ES362130A patent/ES362130A1/en not_active Expired
- 1969-01-17 NL NL6900831A patent/NL6900831A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH510054A (en) | 1971-07-15 |
| DE1814671C3 (en) | 1974-10-17 |
| NL6900831A (en) | 1969-07-22 |
| BE725326A (en) | 1969-05-16 |
| FR1601504A (en) | 1970-08-24 |
| DE1814671B2 (en) | 1974-02-28 |
| DE1814671A1 (en) | 1969-10-02 |
| BR6805051D0 (en) | 1973-01-16 |
| GB1220500A (en) | 1971-01-27 |
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