ES372009A1 - IMPROVEMENTS INTRODUCED IN A PROCEDURE FOR THE PREPARATION OF A DRUG COMBINATION CAPABLE OF INCREASING THE DOPAMINE CONTENT OF THE BRAIN TISSUE. - Google Patents

IMPROVEMENTS INTRODUCED IN A PROCEDURE FOR THE PREPARATION OF A DRUG COMBINATION CAPABLE OF INCREASING THE DOPAMINE CONTENT OF THE BRAIN TISSUE.

Info

Publication number
ES372009A1
ES372009A1 ES372009A ES372009A ES372009A1 ES 372009 A1 ES372009 A1 ES 372009A1 ES 372009 A ES372009 A ES 372009A ES 372009 A ES372009 A ES 372009A ES 372009 A1 ES372009 A1 ES 372009A1
Authority
ES
Spain
Prior art keywords
procedure
increasing
preparation
brain tissue
drug combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES372009A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES372009A1 publication Critical patent/ES372009A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Pharmaceutical compositions comprise L- dopa or a pharmaceutically acceptable salt thereof together with a [alpha]-hydrazino-[alpha]-R-3,4- dihydroxyphenyl-propionic acid or a pharmaceutically acceptable salt thereof, where R represents a hydrogen atom or a C 1 -C 4 alkyl radical. The hydrazine compound may be present as the D, L or racemic forms. A diluent, carrier, coating and/or excipient may be present.
ES372009A 1968-10-01 1969-09-29 IMPROVEMENTS INTRODUCED IN A PROCEDURE FOR THE PREPARATION OF A DRUG COMBINATION CAPABLE OF INCREASING THE DOPAMINE CONTENT OF THE BRAIN TISSUE. Expired ES372009A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76432568A 1968-10-01 1968-10-01
US83573069A 1969-06-23 1969-06-23

Publications (1)

Publication Number Publication Date
ES372009A1 true ES372009A1 (en) 1972-05-01

Family

ID=27117439

Family Applications (1)

Application Number Title Priority Date Filing Date
ES372009A Expired ES372009A1 (en) 1968-10-01 1969-09-29 IMPROVEMENTS INTRODUCED IN A PROCEDURE FOR THE PREPARATION OF A DRUG COMBINATION CAPABLE OF INCREASING THE DOPAMINE CONTENT OF THE BRAIN TISSUE.

Country Status (10)

Country Link
BE (1) BE739625A (en)
CA (1) CA957945A (en)
CY (1) CY648A (en)
DE (1) DE1949376C3 (en)
ES (1) ES372009A1 (en)
FR (1) FR2019605B1 (en)
GB (1) GB1243474A (en)
IE (1) IE33581B1 (en)
IL (1) IL33072A (en)
NL (1) NL149372B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU464903B2 (en) * 1970-11-12 1975-09-11 Merck & Co., Inc Treatment of hypertension
DE4101873C2 (en) * 1991-01-23 1993-12-09 Isis Pharma Gmbh Orally administrable drug form for the treatment of central dopamine deficiency states

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3462536A (en) * 1960-07-22 1969-08-19 Merck & Co Inc Method of inhibiting decarboxylase

Also Published As

Publication number Publication date
NL6914185A (en) 1970-04-03
GB1243474A (en) 1971-08-18
IL33072A0 (en) 1969-11-30
FR2019605A1 (en) 1970-07-03
IE33581L (en) 1970-04-01
BE739625A (en) 1970-03-31
NL149372B (en) 1976-05-17
DE1949376A1 (en) 1970-06-18
CA957945A (en) 1974-11-19
IL33072A (en) 1973-04-30
DE1949376B2 (en) 1977-10-06
CY648A (en) 1972-07-04
IE33581B1 (en) 1974-08-21
DE1949376C3 (en) 1978-08-31
FR2019605B1 (en) 1973-06-08

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