ES372011A2 - Procedure for the manufacture of new tetracycline compounds. (Machine-translation by Google Translate, not legally binding)
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Procedure for the manufacture of new tetracycline compounds. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Ferrer Internacional SA
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Laboratorios Ferrer SL
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Priority to ES372011ApriorityCriticalpatent/ES372011A2/en
Publication of ES372011A2publicationCriticalpatent/ES372011A2/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Improvements in the object of the patent of invention no. 302,954 which relates to the process of manufacturing new tetracycline compounds characterized in that the reaction of the sulfonic group of the balsamic derivative with the dimethylsmino group of the tetracycline, is carried out by reacting a salt alkali of the phenolsulfonic acid with the tetracycline hydrochloride or its derivatives, under such conditions, that the acid radical of the tetracycline salt reacts with the alkaline base of the phenolsulfonic salt with formation of the corresponding alkali chloride, this reaction being carried out in a liquid medium in which the phenolsulfonic compound of the tetracycline is soluble but neither the alkaline salt of the phenolsulfonic acid nor the resulting alkali metal chloride is soluble in order to separate it afterwards by precipitation and then the resulting solution is treated with another solvent in which the liquid medium previously used but it is not the phenolsulfonic compound of tetracycline, which is separated by precipitation and further centrifugation, and then said compound is dried. (Machine-translation by Google Translate, not legally binding)
ES372011A1969-09-291969-09-29Procedure for the manufacture of new tetracycline compounds. (Machine-translation by Google Translate, not legally binding)
ExpiredES372011A2
(en)
A procedure to manufacture a product of trimetafosfatosodico crystalline substantially soluble in water. (Machine-translation by Google Translate, not legally binding)
A procedure for the obtaining of salts with sulphonic acids with alpha-amino-bencil-penicillin. (Machine-translation by Google Translate, not legally binding)