ES373377A1 - Procedimiento para la obtencion de quinalozinonas. - Google Patents

Procedimiento para la obtencion de quinalozinonas.

Info

Publication number: ES373377A1
Authority: ES; Spain
Prior art keywords: quinazolinones; aryl; substituted; pharmaceutical agents; quinazolinone
Prior art date: 1968-11-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES373377A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sandoz AG

Original Assignee

Sandoz AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1968-11-12

Filing date

1969-11-10

Publication date

1972-05-16

1969-11-10 Application filed by Sandoz AG filed Critical Sandoz AG

1972-05-16 Publication of ES373377A1 publication Critical patent/ES373377A1/es

Status Expired legal-status Critical Current

Links

239000008177 pharmaceutical agent Substances 0.000 title 1
JQSGYWDRDFLCPD-UHFFFAOYSA-N 1-ethyl-4-phenylquinazolin-2-one Chemical compound N=1C(=O)N(CC)C2=CC=CC=C2C=1C1=CC=CC=C1 JQSGYWDRDFLCPD-UHFFFAOYSA-N 0.000 abstract 1
229940035676 analgesics Drugs 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
230000001754 anti-pyretic effect Effects 0.000 abstract 1
239000002221 antipyretic Substances 0.000 abstract 1
229940125716 antipyretic agent Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

ES373377A 1968-11-12 1969-11-10 Procedimiento para la obtencion de quinalozinonas. Expired ES373377A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US00775201A US3723432A (en)	1968-11-12	1968-11-12	1-substituted-4-aryl-2(1h)-quinazolinones and their preparation

Publications (1)

Publication Number	Publication Date
ES373377A1 true ES373377A1 (es)	1972-05-16

Family

ID=25103642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES373377A Expired ES373377A1 (es)	1968-11-12	1969-11-10	Procedimiento para la obtencion de quinalozinonas.

Country Status (19)

Country	Link
US (2)	US3723432A (2)
AT (4)	AT310176B (2)
BE (1)	BE741529A (2)
BG (10)	BG16042A3 (2)
BR (1)	BR6914095D0 (2)
CH (1)	CH521972A (2)
DE (1)	DE1956384C3 (2)
DK (1)	DK129347B (2)
ES (1)	ES373377A1 (2)
FR (1)	FR2024830B1 (2)
GB (1)	GB1282612A (2)
IE (1)	IE33933B1 (2)
IL (1)	IL33348A (2)
NL (1)	NL6916514A (2)
NO (1)	NO124032B (2)
OA (1)	OA03829A (2)
PL (1)	PL72695B1 (2)
SE (2)	SE374920B (2)
ZA (1)	ZA697910B (2)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3923803A (en) *	1968-07-18	1975-12-02	Sumitomo Chemical Co	2(1H)-Quinozalinones and process therefor
US3642791A (en) *	1969-08-13	1972-02-15	Sandoz Ag	Morpholino-1-substituted-2(1h)-quinazolinones
US4208343A (en) *	1970-10-30	1980-06-17	Westinghouse Electric Corp.	2,4 Diamino benzonitrile
BE785937A (fr) *	1971-07-08	1973-01-08	Sandoz Sa	Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments
US3937705A (en) *	1972-03-09	1976-02-10	Sandoz, Inc.	1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone
US4071516A (en) *	1976-08-20	1978-01-31	Sandoz, Inc.	4-(Acyloxyphenyl)-quinazolin-2(1H)-ones
US4064246A (en) *	1976-10-12	1977-12-20	Sandoz, Inc.	Hydroxymethyl-substituted-2(1H)-quinazolinones
US4160092A (en) *	1977-06-16	1979-07-03	E. I. Du Pont De Nemours And Company	Quinazolinone oxides and their use as intermediates for pharmaceutical agents
US4224328A (en) *	1979-04-11	1980-09-23	Sandoz, Inc.	Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors
CH645362A5 (de) *	1979-07-05	1984-09-28	Sandoz Ag	Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen.
FR2676042B1 (fr) *	1991-05-02	1993-07-23	Commissariat Energie Atomique	Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium.
US6545004B1 (en)	1999-10-27	2003-04-08	Cytokinetics, Inc.	Methods and compositions utilizing quinazolinones
US7230000B1 (en)	1999-10-27	2007-06-12	Cytokinetics, Incorporated	Methods and compositions utilizing quinazolinones
AR038658A1 (es) *	2001-06-15	2005-01-26	Novartis Ag	Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
AU2002346471A1 (en) *	2001-11-20	2003-06-10	Cytokinetics, Inc.	Process for the racemization of chiral quinazolinones
WO2003070701A2 (en) *	2002-02-15	2003-08-28	Cytokinetics, Inc.	Syntheses of quinazolinones
US7214800B2 (en) *	2002-05-09	2007-05-08	Cytokinetics, Inc.	Compounds, compositions, and methods
CA2485148A1 (en) *	2002-05-09	2003-11-20	Cytokinetics, Inc.	Pyrimidinone compounds, compositions and methods
EP1513820A4 (en) *	2002-05-23	2006-09-13	Cytokinetics Inc	COMPOUNDS, COMPOSITIONS AND METHODS
WO2003106426A1 (en) *	2002-06-14	2003-12-24	Cytokinetics, Inc.	Compounds, compositions, and methods
AU2003256805A1 (en) *	2002-07-23	2004-02-09	Cytokinetics, Inc.	Compounds compositions and methods
US20040048853A1 (en) *	2002-08-21	2004-03-11	Gustave Bergnes	Compounds, compositions, and methods
WO2004034972A2 (en) *	2002-09-30	2004-04-29	Cytokinetics, Inc.	Compounds, compositions, and methods
GB0230015D0 (en) *	2002-12-23	2003-01-29	Novartis Ag	Organic compounds
US8410102B2 (en)	2003-05-27	2013-04-02	Galderma Laboratories Inc.	Methods and compositions for treating or preventing erythema
US7439241B2 (en) *	2003-05-27	2008-10-21	Galderma Laboratories, Inc.	Compounds, formulations, and methods for treating or preventing rosacea
JP2007510652A (ja) *	2003-11-03	2007-04-26	サイトキネティクス・インコーポレーテッド	ピリミジン−４−オン化合物、組成物、および方法
EP1680420A4 (en) *	2003-11-07	2008-09-24	Cytokinetics Inc	COMPOUNDS, COMPOSITIONS AND METHODS
EP1692112A4 (en) *	2003-12-08	2008-09-24	Cytokinetics Inc	COMPOUNDS, COMPOSITIONS, AND METHODS
AU2008268613A1 (en) *	2007-06-22	2008-12-31	Arqule, Inc.	Quinazolinone compounds and methods of use thereof
US8058469B2 (en) *	2008-11-03	2011-11-15	Sabic Innovative Plastics Ip B.V.	Method for making carbamates, ureas and isocyanates
EP2329849B1 (en)	2009-11-18	2015-04-29	Galderma Research & Development	Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder
US8394800B2 (en) *	2009-11-19	2013-03-12	Galderma Laboratories, L.P.	Method for treating psoriasis
US8513247B2 (en)	2010-03-26	2013-08-20	Galderma Laboratories, L.P.	Methods and compositions for safe and effective treatment of erythema
MX2012010823A (es)	2010-03-26	2012-10-10	Galderma Res & Dev	Metodos y composiciones mejoradas para tratamiento seguro y efectivo de telangiectasia.
US8053427B1 (en)	2010-10-21	2011-11-08	Galderma R&D SNC	Brimonidine gel composition
RU2571277C2 (ru)	2010-10-21	2015-12-20	Галдерма С.А.	Композиции геля с бримонидином и способы применения

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3452041A (en) *	1965-05-19	1969-06-24	American Home Prod	Hydantoin compounds and methods of preparation

1968
- 1968-11-12 BG BG015055A patent/BG16042A3/bg unknown
- 1968-11-12 US US00775201A patent/US3723432A/en not_active Expired - Lifetime
1969
- 1969-10-31 GB GB53620/69A patent/GB1282612A/en not_active Expired
- 1969-10-31 CH CH1624569A patent/CH521972A/de not_active IP Right Cessation
- 1969-11-03 NL NL6916514A patent/NL6916514A/xx not_active Application Discontinuation
- 1969-11-07 FR FR696938404A patent/FR2024830B1/fr not_active Expired
- 1969-11-10 DE DE1956384A patent/DE1956384C3/de not_active Expired
- 1969-11-10 BG BG014692A patent/BG16036A3/bg unknown
- 1969-11-10 IE IE1526/69A patent/IE33933B1/xx unknown
- 1969-11-10 AT AT993571A patent/AT310176B/de not_active IP Right Cessation
- 1969-11-10 BE BE741529A patent/BE741529A/xx unknown
- 1969-11-10 BG BG014696A patent/BG16040A3/bg unknown
- 1969-11-10 ES ES373377A patent/ES373377A1/es not_active Expired
- 1969-11-10 BG BG015469A patent/BG16043A3/bg unknown
- 1969-11-10 AT AT993271A patent/AT319950B/de not_active IP Right Cessation
- 1969-11-10 AT AT993071A patent/AT319949B/de not_active IP Right Cessation
- 1969-11-10 BG BG014694A patent/BG16038A3/bg unknown
- 1969-11-10 BG BG014695A patent/BG16039A3/bg unknown
- 1969-11-10 BG BG013325A patent/BG16188A3/bg unknown
- 1969-11-10 BG BG014693A patent/BG16037A3/bg unknown
- 1969-11-10 NO NO4445/69A patent/NO124032B/no unknown
- 1969-11-10 OA OA53783A patent/OA03829A/xx unknown
- 1969-11-10 AT AT1053269A patent/AT310169B/de not_active IP Right Cessation
- 1969-11-11 DK DK597169AA patent/DK129347B/da unknown
- 1969-11-11 BR BR214095/69A patent/BR6914095D0/pt unknown
- 1969-11-11 SE SE6915448A patent/SE374920B/xx unknown
- 1969-11-11 SE SE7213438A patent/SE376917B/xx unknown
- 1969-11-11 IL IL33348A patent/IL33348A/xx unknown
- 1969-11-12 ZA ZA697910A patent/ZA697910B/xx unknown
- 1969-11-12 PL PL1969136872A patent/PL72695B1/pl unknown
1970
- 1970-05-16 BG BG014697A patent/BG16041A3/bg unknown
- 1970-08-13 BG BG015468A patent/BG15573A3/bg unknown
1972
- 1972-12-08 US US313531A patent/US3925548A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IL33348A (en)	1973-04-30
BR6914095D0 (pt)	1973-02-13
DK129347C (2)	1975-02-17
BG16038A3 (bg)	1972-05-20
BG16039A3 (bg)	1972-05-20
DE1956384A1 (de)	1970-06-11
AT310169B (de)	1973-09-25
SU366612A3 (2)	1973-01-16
ZA697910B (en)	1971-07-28
USB313531I5 (2)	1975-01-28
AT310176B (de)	1973-09-25
DE1956384B2 (de)	1980-02-07
SE374920B (2)	1975-03-24
AT319950B (de)	1975-01-10
BG16042A3 (bg)	1972-05-20
NL6916514A (2)	1970-05-14
IE33933L (en)	1970-05-12
DE1956384C3 (de)	1980-10-09
BG16036A3 (bg)	1972-05-20
SE376917B (2)	1975-06-16
BG16041A3 (bg)	1972-05-20
AT319949B (de)	1975-01-10
DK129347B (da)	1974-09-30
US3925548A (en)	1975-12-09
BG16043A3 (bg)	1972-05-20
US3723432A (en)	1973-03-27
BE741529A (2)	1970-05-11
NO124032B (2)	1972-02-21
BG16040A3 (bg)	1972-05-20
BG15573A3 (bg)	1976-06-26
OA03829A (fr)	1971-12-24
BG16037A3 (bg)	1972-05-20
PL72695B1 (en)	1974-08-30
FR2024830A1 (2)	1970-09-04
IE33933B1 (en)	1974-12-11
IL33348A0 (en)	1970-01-29
FR2024830B1 (2)	1973-07-13
CH521972A (de)	1972-04-30
BG16188A3 (bg)	1972-07-20
GB1282612A (en)	1972-07-19

Publication	Publication Date	Title
ES373377A1 (es)	1972-05-16	Procedimiento para la obtencion de quinalozinonas.
AU471598B2 (en)	1976-04-29	2-amidazolin 2-ylamino substituted quinoxaline and quinazolines as antihypertensive agents
SE402283B (sv)	1978-06-26	Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan
FI50707C (fi)	1976-06-10	Menetelmä uusien farmakologisesti vaikuttavien hydroksisykloheksyyliam iinien valmistamiseksi.
PH9276A (en)	1975-08-05	3,4-dihydro-2(1h)-quinazolinones
MY7300287A (en)	1973-12-31	Pyrimidine derivatives and the use thereof as fungicides
OA03836A (fr)	1971-12-24	Nouvelles isoxazolo-pyrimidines et leur application comme herbicides.
DK127332B (da)	1973-10-22	Analogifremgangsmåde til fremstilling af terapeutisk virksomme 1-substituerede 2[1H]-quinazolinoner.
SU444367A3 (ru)	1974-09-25	Способ получения 2(1н)хиназолинонов
OA03710A (fr)	1971-12-24	Composition d'engrais.
IE35594L (en)	1972-03-09	N-(bicycloamino-alkanoyl)-anilines
ES343018A1 (es)	1968-10-16	Procedimiento para la fabricacion de difluoroclorometilari-lureas.
IL36598A0 (en)	1971-06-23	The use of derivatives of n-aryl-oxazolidine-2,4-diones as fungicides,and certain new compounds of this class
IT962172B (it)	1973-12-20	Perfezionamento nei procedimenti e dispositivi per la spruzzatura di materiali alla fiamma di plasma
CH468457A (de)	1969-02-15	Rotlumineszierendes Stoffgemisch und dessen Verwendung
FR1405935A (fr)	1965-07-16	Perfectionnement apporté aux panneaux publicitaires plus spécialement utilisables le long des axes routiers
AU260244B2 (en)	1964-02-13	Quinazoline 3-oxide derivatives
CA688318A (en)	1964-06-09	Steel shelving construction
CA988852A (en)	1976-05-11	Pharmaceutical composition and method of using the same
ES142271Y (es)	1969-10-01	Pabellon para exhibicion de espectaculo publico ambulante.
DK127187B (da)	1973-10-01	Analogifremgangsmåde til fremstilling af 1-propargyl-4-phenyl-2(1H)-quinazolinoner.
AU463486B2 (en)	1972-11-30	Substituted uretidine-2, 4-diones and their use as herbicides
FI41554C (fi)	1969-12-10	Sätt att framställa farmakologiskt värdefulla 4-amino-6,7-di(lägre)alkoksikinoliner
CA699895A (en)	1964-12-15	Amine mercapto-succinates, the preparation thereof and therapeutic applications
CA683789A (en)	1964-04-07	5-arylmercapto pyrimidine intermediates and their manufacture