ES376162A1 - Un procedimiento para preparar 3-amino-2-(3,4-disustituido), biciclo (2.2.2) octan-2-oles. - Google Patents
Un procedimiento para preparar 3-amino-2-(3,4-disustituido), biciclo (2.2.2) octan-2-oles.Info
- Publication number
- ES376162A1 ES376162A1 ES376162A ES376162A ES376162A1 ES 376162 A1 ES376162 A1 ES 376162A1 ES 376162 A ES376162 A ES 376162A ES 376162 A ES376162 A ES 376162A ES 376162 A1 ES376162 A1 ES 376162A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- see formula
- lower alcohol
- octan
- bicyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- BDNQWBJLWGNPAL-UHFFFAOYSA-N bicyclo[2.2.2]octan-3-ol Chemical compound C1CC2C(O)CC1CC2 BDNQWBJLWGNPAL-UHFFFAOYSA-N 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- -1 (3,4-disubstituted) bicyclo [2.2.2] octan-2-ol Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/44—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton bound to carbon atoms of the same ring or condensed ring system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79723369A | 1969-02-06 | 1969-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES376162A1 true ES376162A1 (es) | 1972-03-01 |
Family
ID=25170288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES376162A Expired ES376162A1 (es) | 1969-02-06 | 1970-02-03 | Un procedimiento para preparar 3-amino-2-(3,4-disustituido), biciclo (2.2.2) octan-2-oles. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3651142A (es) |
| JP (1) | JPS4910950B1 (es) |
| BE (1) | BE745059A (es) |
| DE (1) | DE2003744C2 (es) |
| ES (1) | ES376162A1 (es) |
| FR (1) | FR2034521B1 (es) |
| GB (1) | GB1275875A (es) |
| ZA (1) | ZA70400B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3725477A (en) * | 1971-08-27 | 1973-04-03 | Cities Service Co | Oximino ketones and method for manufacturing amino acids from said ketones |
| US3932425A (en) * | 1974-04-12 | 1976-01-13 | The Upjohn Company | Benzospiran derivatives |
| US4100193A (en) * | 1976-06-10 | 1978-07-11 | Merck & Co., Inc. | Novel dibicyclo [2.2.2] octyl and dibicyclo [2.2.2] octenyl polyamines and methods for their preparation |
| CN111689854A (zh) * | 2020-04-16 | 2020-09-22 | 广东莱佛士制药技术有限公司 | 制备3-羰基-二环[2.2.2]辛烷-2-甲酸酯的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1110159B (de) * | 1959-08-01 | 1961-07-06 | Merck Ag E | Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen |
| DE1110160B (de) * | 1959-08-01 | 1961-07-06 | Merck Ag E | Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen |
-
1969
- 1969-02-06 US US797233A patent/US3651142A/en not_active Expired - Lifetime
-
1970
- 1970-01-20 ZA ZA700400A patent/ZA70400B/xx unknown
- 1970-01-28 DE DE2003744A patent/DE2003744C2/de not_active Expired
- 1970-01-28 BE BE745059D patent/BE745059A/xx not_active IP Right Cessation
- 1970-01-30 GB GB4575/70A patent/GB1275875A/en not_active Expired
- 1970-02-03 ES ES376162A patent/ES376162A1/es not_active Expired
- 1970-02-04 FR FR7003937A patent/FR2034521B1/fr not_active Expired
- 1970-02-04 JP JP45009338A patent/JPS4910950B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US3651142A (en) | 1972-03-21 |
| FR2034521B1 (es) | 1974-02-01 |
| JPS4910950B1 (es) | 1974-03-13 |
| FR2034521A1 (es) | 1970-12-11 |
| DE2003744C2 (de) | 1983-06-09 |
| GB1275875A (en) | 1972-05-24 |
| DE2003744A1 (de) | 1970-09-03 |
| BE745059A (fr) | 1970-07-28 |
| ZA70400B (en) | 1971-08-25 |
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