ES379731A1 - Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos. - Google Patents

Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos.

Info

Publication number
ES379731A1
ES379731A1 ES379731A ES379731A ES379731A1 ES 379731 A1 ES379731 A1 ES 379731A1 ES 379731 A ES379731 A ES 379731A ES 379731 A ES379731 A ES 379731A ES 379731 A1 ES379731 A1 ES 379731A1
Authority
ES
Spain
Prior art keywords
alkyl
propanes
cyanophenoxy
alkylamino
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES379731A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C.H. Boehringer Sohn AG and Co KG
Original Assignee
C.H. Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.H. Boehringer Sohn AG and Co KG filed Critical C.H. Boehringer Sohn AG and Co KG
Publication of ES379731A1 publication Critical patent/ES379731A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES379731A 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos. Expired ES379731A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEB0095902 1967-12-18
DEB0095988 1967-12-22

Publications (1)

Publication Number Publication Date
ES379731A1 true ES379731A1 (es) 1973-01-16

Family

ID=25968397

Family Applications (8)

Application Number Title Priority Date Filing Date
ES361530A Expired ES361530A1 (es) 1967-12-18 1968-12-17 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi 3-sec - alcohilamino propanos racemicos u opticamente activos.
ES379735A Expired ES379735A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos.
ES379736A Expired ES379736A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.
ES379738A Expired ES379738A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.
ES379733A Expired ES379733A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos.
ES379731A Expired ES379731A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos.
ES379737A Expired ES379737A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.
ES379739A Expired ES379739A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de preparados farmaceuti-cos que contienen en calidad de sustancia activa nuevos 1-fenoxi-2-hidroxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES361530A Expired ES361530A1 (es) 1967-12-18 1968-12-17 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi 3-sec - alcohilamino propanos racemicos u opticamente activos.
ES379735A Expired ES379735A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos.
ES379736A Expired ES379736A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.
ES379738A Expired ES379738A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.
ES379733A Expired ES379733A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1 - fenoxi-2- hidroxi-3-sec-alcohilaminopropanos racemicos u opticamente activos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES379737A Expired ES379737A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de nuevos 1-fenoxi-2-hi- droxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.
ES379739A Expired ES379739A1 (es) 1967-12-18 1970-05-16 Procedimiento para la preparacion de preparados farmaceuti-cos que contienen en calidad de sustancia activa nuevos 1-fenoxi-2-hidroxi-3-sec - alcohilaminopropanos racemicos u opticamente activos.

Country Status (11)

Country Link
US (1) US3644469A (es)
JP (1) JPS5210854B1 (es)
BE (1) BE725679A (es)
CA (1) CA956641A (es)
CH (1) CH512427A (es)
DK (1) DK129447B (es)
ES (8) ES361530A1 (es)
FR (2) FR1595323A (es)
GB (1) GB1260848A (es)
NL (1) NL163775C (es)
SE (1) SE358382B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975539A (en) * 1935-11-15 1976-08-17 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing an N,N-bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamine and method of use
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
FR2119843B1 (es) * 1970-12-28 1974-03-22 Laroche Navarro Labo
US4145442A (en) * 1972-04-04 1979-03-20 Aktiebolaget Hassle Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
JPS49245A (es) * 1972-04-17 1974-01-05
ZA741812B (en) * 1973-04-18 1975-04-30 Haessle A New amines and process for their preparation
US4191765A (en) * 1976-05-25 1980-03-04 Hoechst Aktiengesellschaft 1-Aryloxy-2-hydroxy-3-aminopropanes
DE2645710C2 (de) * 1976-10-09 1985-06-27 Merck Patent Gmbh, 6100 Darmstadt Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
US4328213A (en) * 1979-11-28 1982-05-04 Schering Corporation Stable injectable labetalol formulation
US4347177A (en) * 1980-04-14 1982-08-31 Burroughs Wellcome Co. Compounds and methods of making them
SE8004087L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ...
SE8004088L (sv) * 1980-06-02 1981-12-03 Haessle Ab Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ...
US4593119A (en) * 1980-11-28 1986-06-03 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
US4387103A (en) * 1980-11-28 1983-06-07 American Hospital Supply Corporation Method for treatment or prophylaxis of cardiac disorders
JPS60100961U (ja) * 1983-12-15 1985-07-10 豊根　實 植木鉢
DE3512627A1 (de) * 1985-04-06 1986-10-09 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel
US4665094A (en) * 1985-08-29 1987-05-12 Merck & Co., Inc. Oculoselective beta-blockers for treatment of elevated intraocular pressure
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US5480908A (en) * 1993-12-13 1996-01-02 American Cyanamid Company β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions
KR100806326B1 (ko) * 1999-12-14 2008-02-27 쇼와 덴코 가부시키가이샤 시아노벤질아민 염의 제조방법

Also Published As

Publication number Publication date
FR1595323A (es) 1970-06-08
DK129447B (da) 1974-10-14
BE725679A (es) 1969-06-18
NL6818101A (es) 1969-06-20
GB1260848A (en) 1972-01-19
ES379735A1 (es) 1973-01-16
US3644469A (en) 1972-02-22
ES379736A1 (es) 1973-02-01
SE358382B (es) 1973-07-30
ES379739A1 (es) 1973-02-01
NL163775B (nl) 1980-05-16
DK129447C (es) 1975-03-03
CH512427A (de) 1971-09-15
FR8262M (es) 1970-10-19
NL163775C (nl) 1980-10-15
ES379737A1 (es) 1973-02-01
ES361530A1 (es) 1970-11-01
CA956641A (en) 1974-10-22
ES379733A1 (es) 1973-01-16
JPS5210854B1 (es) 1977-03-26
ES379738A1 (es) 1973-02-01

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