ES386601A1 - Un procedimiento de resolucion de 2-(oclorofenil) - 2- me- tilamino-ciclohexanona racemica. - Google Patents
Un procedimiento de resolucion de 2-(oclorofenil) - 2- me- tilamino-ciclohexanona racemica.Info
- Publication number
- ES386601A1 ES386601A1 ES386601A ES386601A ES386601A1 ES 386601 A1 ES386601 A1 ES 386601A1 ES 386601 A ES386601 A ES 386601A ES 386601 A ES386601 A ES 386601A ES 386601 A1 ES386601 A1 ES 386601A1
- Authority
- ES
- Spain
- Prior art keywords
- methylaminocyclohexanone
- chlorophenyl
- tartaric acid
- isomer
- racemic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YQEZLKZALYSWHR-UHFFFAOYSA-N Ketamine Chemical compound C=1C=CC=C(Cl)C=1C1(NC)CCCCC1=O YQEZLKZALYSWHR-UHFFFAOYSA-N 0.000 title abstract 6
- 229960003299 ketamine Drugs 0.000 title 1
- 150000003892 tartrate salts Chemical class 0.000 abstract 2
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88679969A | 1969-12-19 | 1969-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES386601A1 true ES386601A1 (es) | 1974-01-16 |
Family
ID=25389797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES386601A Expired ES386601A1 (es) | 1969-12-19 | 1970-12-18 | Un procedimiento de resolucion de 2-(oclorofenil) - 2- me- tilamino-ciclohexanona racemica. |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4948542B1 (fr) |
| BE (1) | BE760492A (fr) |
| CH (1) | CH535201A (fr) |
| DE (1) | DE2062620A1 (fr) |
| ES (1) | ES386601A1 (fr) |
| FR (1) | FR2081388B1 (fr) |
| GB (1) | GB1330878A (fr) |
| NL (1) | NL7018334A (fr) |
| ZA (1) | ZA708468B (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5875614A (ja) * | 1981-10-28 | 1983-05-07 | Matsushita Electric Ind Co Ltd | 焼却炉の排ガス浄化装置 |
| DE4312016A1 (de) * | 1993-04-13 | 1994-10-20 | Goedecke Ag | Stabile Ketamin-Lösungen |
| DE19619665C2 (de) * | 1996-05-15 | 2001-03-08 | Goedecke Ag | Racemattrennung von Ketamin |
| BRPI0002693B8 (pt) * | 2000-06-19 | 2021-05-25 | Cristalia Produtos Quim Farmaceuticos Ltda | processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis |
| US7273889B2 (en) | 2002-09-25 | 2007-09-25 | Innovative Drug Delivery Systems, Inc. | NMDA receptor antagonist formulation with reduced neurotoxicity |
| US20060063802A1 (en) | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| US9072662B2 (en) | 2004-03-29 | 2015-07-07 | Auris Medical Ag | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| US8268866B2 (en) | 2004-03-29 | 2012-09-18 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| EA017264B1 (ru) | 2005-09-28 | 2012-11-30 | Аурис Медикаль Аг | Применение композиции арилциклоалкиламида для получения лекарственного препарата для лечения нарушения внутреннего уха |
| JP5941159B2 (ja) | 2011-12-12 | 2016-06-29 | オトラーヌム アーゲー | 聴覚系における塩素イオン共輸送体ｎｋｃｃ１の調節による耳鳴の治療 |
| MX371392B (es) | 2013-03-15 | 2020-01-28 | Janssen Pharmaceutica Nv | Composicion farmaceutica de clorhidrato de s-ketamina. |
| EP3964203A1 (fr) | 2013-09-13 | 2022-03-09 | National University Corporation Chiba University | R-kétamine et de ses sels comme médicaments |
| JP6545788B2 (ja) | 2014-08-13 | 2019-07-17 | ヤンセン ファーマシューティカ エヌ．ベー． | うつ病の治療方法 |
| US20160074340A1 (en) | 2014-09-15 | 2016-03-17 | Janssen Pharmaceutica Nv | VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION |
| US20160332962A1 (en) * | 2015-05-13 | 2016-11-17 | Janssen Pharmaceutica Nv | (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| KR20200113197A (ko) | 2017-12-22 | 2020-10-06 | 얀센 파마슈티칼즈, 인코포레이티드 | 우울증 치료를 위한 에스케타민 |
| EP3753557B1 (fr) | 2018-02-15 | 2025-11-05 | National University Corporation Chiba University | Agent prophylactique ou thérapeutique et composition pharmaceutique contre des maladies inflammatoires ou des maladies osseuses |
| CN110218157B (zh) * | 2018-03-01 | 2022-08-23 | 江苏恒瑞医药股份有限公司 | 一种r-氯胺酮及其可药用盐的制备方法 |
| CN112533595A (zh) | 2018-05-04 | 2021-03-19 | 感知神经科学公司 | 治疗物质滥用的方法 |
| JP2021529732A (ja) | 2018-06-27 | 2021-11-04 | クレキシオ バイオサイエンシーズ エルティーディー． | 大うつ病性障害の処置方法 |
| EP3860579A1 (fr) | 2018-10-05 | 2021-08-11 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
| WO2020070547A1 (fr) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
| WO2020070706A1 (fr) | 2018-10-05 | 2020-04-09 | Clexio Biosciences Ltd. | Régime posologique d'eskétamine pour le traitement d'un trouble dépressif majeur |
| WO2020075134A1 (fr) | 2018-10-11 | 2020-04-16 | Clexio Biosciences Ltd. | Eskétamine pour une utilisation dans le traitement d'un trouble dépressif majeur |
| EP3934632A4 (fr) | 2019-03-05 | 2022-11-23 | Janssen Pharmaceuticals, Inc. | Eskétamine pour le traitement de la dépression |
| US12478592B2 (en) | 2019-12-30 | 2025-11-25 | Clexio Biosciences Ltd. | Dosage regime with esketamine for treating neuropsychiatric or neurological conditions |
| WO2021137148A1 (fr) | 2019-12-30 | 2021-07-08 | Clexio Biosciences Ltd. | Régime posologique à base d'eskétamine pour le traitement de troubles neuropsychiatriques ou neurologiques |
| WO2021137147A1 (fr) | 2019-12-30 | 2021-07-08 | Clexio Biosciences Ltd. | Régime posologique à base d'eskétamine pour le traitement d'un trouble dépressif majeur |
| CA3164022A1 (fr) | 2020-01-22 | 2021-07-29 | Raj Mehra | Reduction des effets secondaires d'antagonistes de nmda |
| CN112125816A (zh) * | 2020-03-17 | 2020-12-25 | 国药集团工业有限公司 | 一种氯胺酮、其衍生物或其盐的消旋化方法 |
| US20250082587A1 (en) | 2023-09-12 | 2025-03-13 | Clexio Biosciences Ltd. | Method Of Treating Major Depressive Disorder |
-
1970
- 1970-12-11 CH CH1836870A patent/CH535201A/de not_active IP Right Cessation
- 1970-12-15 ZA ZA708468A patent/ZA708468B/xx unknown
- 1970-12-16 NL NL7018334A patent/NL7018334A/xx unknown
- 1970-12-17 BE BE760492A patent/BE760492A/fr unknown
- 1970-12-18 GB GB6017370A patent/GB1330878A/en not_active Expired
- 1970-12-18 ES ES386601A patent/ES386601A1/es not_active Expired
- 1970-12-18 DE DE19702062620 patent/DE2062620A1/de active Pending
- 1970-12-18 FR FR7045893A patent/FR2081388B1/fr not_active Expired
- 1970-12-19 JP JP11363170A patent/JPS4948542B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2081388B1 (fr) | 1974-06-21 |
| BE760492A (fr) | 1971-06-17 |
| GB1330878A (en) | 1973-09-19 |
| NL7018334A (fr) | 1971-06-22 |
| DE2062620A1 (de) | 1971-07-15 |
| FR2081388A1 (fr) | 1971-12-03 |
| CH535201A (de) | 1973-03-31 |
| JPS4948542B1 (fr) | 1974-12-21 |
| ZA708468B (en) | 1972-02-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES386601A1 (es) | Un procedimiento de resolucion de 2-(oclorofenil) - 2- me- tilamino-ciclohexanona racemica. | |
| DK402075A (da) | Fremgangsmade til fremstilling af organiske forbindelser, der indeholder cyclopropanringsystemet | |
| CH390916A (de) | Verfahren zur Herstellung von pharmakologisch wirksamen organischen Verbindungen | |
| AT269089B (de) | Verfahren zur Herstellung organischer Verbindungen | |
| IT1076807B (it) | Procedimento per produrre composti organici del fosforo contenenti gruppi carbossilici | |
| ES386969A1 (es) | Un metodo para preparar una amidinourea. | |
| NL7600467A (nl) | Werkwijze ter bereiding van wijnsteenzuur. | |
| NL7603105A (nl) | Werkwijze ter bereiding van geperfluoreerde carbonylverbindingen. | |
| ES390110A1 (es) | Un procedimiento para la preparacion de nuevos compuestos organicos biciclicos. | |
| CH449010A (de) | Verfahren zur Herstellung organischer Borverbindungen | |
| CH410941A (de) | Verfahren zur Herstellung von organischen Phosphorthioverbindungen | |
| CH553744A (de) | Verfahren zur herstellung aromatischer dinitrohalogenverbindungen. | |
| DK357676A (da) | Fremgangsmade til fremstilling af organiske forbindelser | |
| NO142864C (no) | Fremgangsmaate for asymmetrisk hydrogenering av prochirale eller racemiske forbindelser ved hjelp av amino- eller polyiminoalaner | |
| CH453346A (de) | Verfahren zur Herstellung organischer Verbindungen | |
| CH422777A (de) | Verfahren zur Herstellung neuer organischer Phosphorverbindungen | |
| ES306001A1 (es) | Procedimiento de preparacion de medios fungicidas. | |
| ES413271A1 (es) | Un procedimiento para la preparacion de acido 5-fluor-2-me-til-1-(p,metilsulfinilbenciliden)-3-indenil-acetica. | |
| ES285790A1 (es) | Procedimiento para la producción de succinimidas | |
| ES461637A1 (es) | Un procedimiento para la preparacion de compuestos tiazoli- nil cetobenzimidazoles. | |
| DD138471A3 (de) | Verfahren zur gezielten herstellung von derivaten nieder-bis hochfluorierter kohlenwasserstoffe | |
| CH437255A (de) | Verfahren zur Herstellung von hochfluorierten organischen Verbindungen | |
| ES357243A3 (es) | Procedimiento de preparacion de esteres heterociclicos de metil-5-hidroxi-8 quinoleina. | |
| DK104677C (da) | Fremgangsmåde til fremstilling af 3-halogen-iminodibenzylforbindelser. | |
| ES282613A1 (es) | Procedimiento de obtención de compuestos de naftaleno |