ES387399A3 - PROCEDURE FOR THE PREPARATION OF NEW IMIDAZOLINE DERIVATIVES. - Google Patents
PROCEDURE FOR THE PREPARATION OF NEW IMIDAZOLINE DERIVATIVES.Info
- Publication number
- ES387399A3 ES387399A3 ES387399A ES387399A ES387399A3 ES 387399 A3 ES387399 A3 ES 387399A3 ES 387399 A ES387399 A ES 387399A ES 387399 A ES387399 A ES 387399A ES 387399 A3 ES387399 A3 ES 387399A3
- Authority
- ES
- Spain
- Prior art keywords
- ethylenediamine
- derivatives
- formula
- dimethoxy
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002462 imidazolines Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- -1 2,5-dimethoxyphenyl Chemical group 0.000 abstract 4
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A procedure for the preparation of new imidazoline derivatives of formula I **(See formula)** in which R stands for 2,5-dimethoxyphenyl, 2,5-dimethoxy-4,6-dimethylphenyl, 2,5-dimethoxy-3,4,6-trimethylphenyl, or 2,5-dimethoxy-3,6-dimethylphenyl, as well as their acid addition salts, characterized in that a carboxylic acid of the formula R-CH2-COOH is reacted hot, in which R has the same meaning already expressed for formula (I), or one of its functional derivatives, with ethylenediamine and, optionally, its mono-p-toluenesulfonate; whose reaction, if any, is conducted in such a way that the functional acid derivatives are formed during the reaction, as well as, if necessary, the "in situ" formation of ethylenediamine from its N-derivatives, under the same Reactional conditions of condensation with the acid, or the formation "in situ" of ethylenediamine by reaction of ammonia, or agents that yield it, with a compound transformable by it in ethylenediamine. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES387399A ES387399A3 (en) | 1971-01-19 | 1971-01-19 | PROCEDURE FOR THE PREPARATION OF NEW IMIDAZOLINE DERIVATIVES. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES387399A ES387399A3 (en) | 1971-01-19 | 1971-01-19 | PROCEDURE FOR THE PREPARATION OF NEW IMIDAZOLINE DERIVATIVES. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES387399A3 true ES387399A3 (en) | 1974-08-01 |
Family
ID=8457650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES387399A Expired ES387399A3 (en) | 1971-01-19 | 1971-01-19 | PROCEDURE FOR THE PREPARATION OF NEW IMIDAZOLINE DERIVATIVES. |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES387399A3 (en) |
-
1971
- 1971-01-19 ES ES387399A patent/ES387399A3/en not_active Expired
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