ES390235A1 - Process for the production of 6-amino-penicillanic acid derivatives - Google Patents
Process for the production of 6-amino-penicillanic acid derivativesInfo
- Publication number
- ES390235A1 ES390235A1 ES390235A ES390235A ES390235A1 ES 390235 A1 ES390235 A1 ES 390235A1 ES 390235 A ES390235 A ES 390235A ES 390235 A ES390235 A ES 390235A ES 390235 A1 ES390235 A1 ES 390235A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- amino
- penicillanic acid
- production
- acid derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical class [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000346 malonyl group Chemical group C(CC(=O)*)(=O)* 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- -1 silyl ester Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of penicillin derivatives of the formula I and salts thereof, comprising reacting a 6-amino-penicillanic acid trialkoyl silyl ester of the formula II with a malonyl dihalide of the formula III, hydrolyze thereafter the compound of formula IV thus obtained and, if desired, liberating a compound thus obtained from its salt or converting it into a salt (in which formulas R represents an optionally substituted aromatic or heterocyclic radical; R1 represents an alcohol radical and X represents a halogen). (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000980 | 1970-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES390235A1 true ES390235A1 (en) | 1973-07-01 |
Family
ID=10994378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES390235A Expired ES390235A1 (en) | 1970-04-16 | 1971-04-15 | Process for the production of 6-amino-penicillanic acid derivatives |
Country Status (7)
| Country | Link |
|---|---|
| AT (1) | AT303964B (en) |
| CH (1) | CH550198A (en) |
| DK (1) | DK130682B (en) |
| ES (1) | ES390235A1 (en) |
| GB (1) | GB1308858A (en) |
| NL (1) | NL7105083A (en) |
| SU (1) | SU419038A3 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3862933A (en) * | 1972-07-12 | 1975-01-28 | Pfizer | Process for making esters of 6-(alpha-(carboxy)aryla-cetamido)penicillanic acids |
-
1971
- 1971-04-15 CH CH546871A patent/CH550198A/en not_active IP Right Cessation
- 1971-04-15 SU SU1650120A patent/SU419038A3/en active
- 1971-04-15 ES ES390235A patent/ES390235A1/en not_active Expired
- 1971-04-15 NL NL7105083A patent/NL7105083A/xx unknown
- 1971-04-16 DK DK182571A patent/DK130682B/en unknown
- 1971-04-16 AT AT322071A patent/AT303964B/en not_active IP Right Cessation
- 1971-04-19 GB GB2729571A patent/GB1308858A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK130682B (en) | 1975-03-24 |
| CH550198A (en) | 1974-06-14 |
| SU419038A3 (en) | 1974-03-05 |
| GB1308858A (en) | 1973-03-07 |
| NL7105083A (en) | 1971-10-19 |
| AT303964B (en) | 1972-12-27 |
| DK130682C (en) | 1975-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES415744A1 (en) | Process for manufacturing heterocyclic compounds | |
| ES457993A1 (en) | Isothiazolo-pyridines | |
| ES413267A1 (en) | A PROCEDURE FOR THE PREPARATION OF A DERIVATIVE OF INDENILACETIC ACI-DO. | |
| ES404744A1 (en) | Cephalosporin derivatives | |
| ES390235A1 (en) | Process for the production of 6-amino-penicillanic acid derivatives | |
| ES405555A1 (en) | 7-Alkoxycarbonyl-4-hydroxymethyl-1-phthalazone compounds | |
| ES446187A1 (en) | Oxime ethers having anti-depressive activity | |
| ES394894A1 (en) | Phenylacetohydroxamic acids process for their manufacture and preparations containing them | |
| ES412068A1 (en) | Xylidides | |
| ES401829A1 (en) | PROCEDURE FOR THE PREPARATION OF COMPOUNDS DERIVED FROM PICOLINIC A-ACID. | |
| ES370442A1 (en) | DERIVATIVES OF alpha-AMINOPENICILLINS | |
| ES395834A1 (en) | Penicillins | |
| ES325448A1 (en) | Procedure for producing 4-amino-5-halo-2-benzamide derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES382852A1 (en) | Procedure for the preparation of new derivatives of 5h-dibenz (b, f) azepine. (Machine-translation by Google Translate, not legally binding) | |
| GB1377886A (en) | 1,2,4-oxadiazole derivatives | |
| ES428011A1 (en) | PROCEDURE FOR THE PREPARATION OF 2-AMINO-3,5-DIBROMO-BENZYLAMINE. | |
| ES389687A1 (en) | A procedure for preparing derivatives of carbonil-dioximorfinan. (Machine-translation by Google Translate, not legally binding) | |
| JPS5283393A (en) | Synthesis of novel penicillin derivatives | |
| ES400988A1 (en) | Procedure for the obtaining of 4-benzamido-n, N-dipropil-glutaramico. (Machine-translation by Google Translate, not legally binding) | |
| ES412886A1 (en) | A procedure for the preparation of tiazolcarboxilic acid derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES395985A1 (en) | A procedure for preparation of imidazopiridincarbamates. (Machine-translation by Google Translate, not legally binding) | |
| ES444195A1 (en) | A procedure for the preparation of clavulan acid. (Machine-translation by Google Translate, not legally binding) | |
| ES398232A1 (en) | A procedure for the preparation of replaced indenilactic acid esters. (Machine-translation by Google Translate, not legally binding) | |
| ES403886A1 (en) | Procedure for preparing amidas of the acid (trimetoxi -3,4,5) cinemico. (Machine-translation by Google Translate, not legally binding) | |
| ES419656A1 (en) | A PROCEDURE FOR THE PRODUCTION OF A COMPOUND OF AN ALYLAMINE-ALKANOLIC ESTER. |