ES399253A1 - Procedure for the preparation of imidazoline derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of imidazoline derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES399253A1 ES399253A1 ES399253A ES399253A ES399253A1 ES 399253 A1 ES399253 A1 ES 399253A1 ES 399253 A ES399253 A ES 399253A ES 399253 A ES399253 A ES 399253A ES 399253 A1 ES399253 A1 ES 399253A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- acid addition
- translation
- preparation
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002462 imidazolines Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for the preparation of imidazoline derivatives, of the general formula: ** (see formula) ** And the pharmaceutically acceptable acid addition salts thereof, in which formula r represents a straight or branched chain alkyl group containing from 1 to 4 carbon atoms; characterized in that ethylenediamine is reacted, in a lower alcohol, with an acid addition salt of a lower alkyl (2-alkylbenzo [b] furan-3-yl) -iminoacetate, of the general formula: ** (see formula) ** Wherein r'represents a lower alkyl group containing from 1 to 4 carbon atoms, x represents the anion of a strong acid and r is defined as above, to form the corresponding acid addition salt of the required compound of general formula i, which can be done; then reacting with a base to obtain the compound of formula i in the form of the free base, which, if desired, can be reacted with an organic or inorganic acid to form a different pharmaceutically acceptable acid addition salt. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES399253A ES399253A1 (en) | 1972-01-27 | 1972-01-27 | Procedure for the preparation of imidazoline derivatives. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES399253A ES399253A1 (en) | 1972-01-27 | 1972-01-27 | Procedure for the preparation of imidazoline derivatives. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES399253A1 true ES399253A1 (en) | 1974-12-01 |
Family
ID=8460160
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES399253A Expired ES399253A1 (en) | 1972-01-27 | 1972-01-27 | Procedure for the preparation of imidazoline derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES399253A1 (en) |
-
1972
- 1972-01-27 ES ES399253A patent/ES399253A1/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES368535A1 (en) | 4 5-dihydrothieno(2 3-b)(1)benzothiepin derivatives as cns depressants | |
| ES438704A1 (en) | Ergot peptide alkaloids | |
| ES391524A1 (en) | 2,3 - dihydro - 5-trifluoromethyl-1h-di-benzo(2,3:6,7)thiepino(4,5-c)pyrroles as cns-depressants | |
| ES441257A1 (en) | Heterocyclic compounds | |
| ES454006A1 (en) | Triazole derivatives and processes for the production thereof | |
| ES429691A1 (en) | Preparation of p-isobutyl hydratropic acid and intermediates therefor | |
| ES386716A1 (en) | Procedure for the preparation of new derivatives of tiepine. (Machine-translation by Google Translate, not legally binding) | |
| ES403910A1 (en) | Imidazo-4,5-b-pyridine derivatives | |
| ES360859A1 (en) | Procedure for the preparation of new derivatives of tiazepine. (Machine-translation by Google Translate, not legally binding) | |
| ES383342A1 (en) | P-carbamoylethylphenylsulfonyl derivatives | |
| ES422006A1 (en) | Procedure for the preparation of N- (heteroaril-methyl) -benzomorphanes and mordinan. (Machine-translation by Google Translate, not legally binding) | |
| ES385062A1 (en) | Derivatives of 1-amino-3-phenoxy-propan-2-ol, and processes for preparing them | |
| ES373929A1 (en) | Procedure for the preparation of new derivatives of azepine. (Machine-translation by Google Translate, not legally binding) | |
| ES415404A1 (en) | Procedure for preparing amino-2 benzoic acid derivatives. (Machine-translation by Google Translate, not legally binding) | |
| GB1217207A (en) | 2,4,6,8-tetrathia-1-adamantanthioles and process for their preparation | |
| ES397708A1 (en) | Procedure for the obtaining derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding) | |
| ES363846A1 (en) | Procedure for the preparation of new derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding) | |
| ES383108A1 (en) | Procedure for the preparation of new derivatives of dibenzociclopropapenteen. (Machine-translation by Google Translate, not legally binding) | |
| ES356530A1 (en) | Procedure for the preparation of new carboxylic derivatives heterociclicos (Machine-translation by Google Translate, not legally binding) | |
| ES296035A1 (en) | Procedure for obtaining benzosulfonilureas (Machine-translation by Google Translate, not legally binding) | |
| ES382611A1 (en) | Procedure for the preparation of new derivatives of imidazolidinone. (Machine-translation by Google Translate, not legally binding) | |
| ES371237A1 (en) | Procedure for the preparation of new benzofuran derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES382147A1 (en) | A procedure for preparing N-substituted morpholine compounds. (Machine-translation by Google Translate, not legally binding) | |
| ES410009A1 (en) | Process for preparing 7-acylamino-3-substituted-3-cephem-4- carboxylic acid derivatives | |
| ES383104A1 (en) | Procedure for the preparation of new derivatives of dibenzociclopropapenteen. (Machine-translation by Google Translate, not legally binding) |