ES402468A1 - A PROCEDURE FOR THE PREPARATION OF VINCAMINE AND SIMILAR COMPOUNDS - Google Patents
A PROCEDURE FOR THE PREPARATION OF VINCAMINE AND SIMILAR COMPOUNDSInfo
- Publication number
- ES402468A1 ES402468A1 ES0402468A ES402468A ES402468A1 ES 402468 A1 ES402468 A1 ES 402468A1 ES 0402468 A ES0402468 A ES 0402468A ES 402468 A ES402468 A ES 402468A ES 402468 A1 ES402468 A1 ES 402468A1
- Authority
- ES
- Spain
- Prior art keywords
- vincamine
- procedure
- preparation
- compounds
- similar compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N vincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 title abstract 7
- 150000001875 compounds Chemical class 0.000 title abstract 5
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 229960002726 vincamine Drugs 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000932 sedative agent Substances 0.000 abstract 1
- 230000001624 sedative effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 229940124549 vasodilator Drugs 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedure for the preparation of vincamine and similar compounds, having the general formula (I) ** formula ** where R represents a C1-5 alkoxy group, or the group R-CO-represents a reactive group that can be converted In an alkoxycarbonyl radical, More particularly, this invention relates to the synthesis of vincamine and the like compounds having the general formula (I), from new intermediate compounds. Furthermore, these new intermediate compounds used as starting substances in the process of the invention possess biological activity, for example, they have a certain vasodilator effect. Nature's (+) - vincamine is known to be an important therapeutic agent, as it has sedative and antihypertensive effects. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0402468A ES402468A1 (en) | 1972-05-06 | 1972-05-06 | A PROCEDURE FOR THE PREPARATION OF VINCAMINE AND SIMILAR COMPOUNDS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0402468A ES402468A1 (en) | 1972-05-06 | 1972-05-06 | A PROCEDURE FOR THE PREPARATION OF VINCAMINE AND SIMILAR COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES402468A1 true ES402468A1 (en) | 1975-12-16 |
Family
ID=59033390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0402468A Expired ES402468A1 (en) | 1972-05-06 | 1972-05-06 | A PROCEDURE FOR THE PREPARATION OF VINCAMINE AND SIMILAR COMPOUNDS |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES402468A1 (en) |
-
1972
- 1972-05-06 ES ES0402468A patent/ES402468A1/en not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19950206 |