ES403631A1 - A method of obtaining two esters of N- (2-hydroxytyl) -pirrolidin. (Machine-translation by Google Translate, not legally binding) - Google Patents

A method of obtaining two esters of N- (2-hydroxytyl) -pirrolidin. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES403631A1
ES403631A1 ES403631A ES403631A ES403631A1 ES 403631 A1 ES403631 A1 ES 403631A1 ES 403631 A ES403631 A ES 403631A ES 403631 A ES403631 A ES 403631A ES 403631 A1 ES403631 A1 ES 403631A1
Authority
ES
Spain
Prior art keywords
translation
obtaining
machine
esters
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES403631A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Made SA
Original Assignee
Laboratorios Made SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Made SA filed Critical Laboratorios Made SA
Priority to ES403631A priority Critical patent/ES403631A1/en
Priority to DE2317219A priority patent/DE2317219A1/en
Publication of ES403631A1 publication Critical patent/ES403631A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method of obtaining two r- (2-hydroxyethyl) -pyrrolidine esters of the formula ** (see formula) ** Wherein r is a di-N-propylmethyl or 3,5-dimethylphenyl radical, characterized in that an activated derivative of the acid, such as the chloride or the anhydride thereof, is reacted with N- (2-hydroxyethyl) -pyrrolidine in the sine of an appropriate solvent, or by direct esterification in the presence of an acid catalyst, purifying the product of the reaction by crystallization or by treatment with a base, extraction in an appropriate solvent, drying and further distillation. (Machine-translation by Google Translate, not legally binding)
ES403631A 1972-06-08 1972-06-08 A method of obtaining two esters of N- (2-hydroxytyl) -pirrolidin. (Machine-translation by Google Translate, not legally binding) Expired ES403631A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES403631A ES403631A1 (en) 1972-06-08 1972-06-08 A method of obtaining two esters of N- (2-hydroxytyl) -pirrolidin. (Machine-translation by Google Translate, not legally binding)
DE2317219A DE2317219A1 (en) 1972-06-08 1973-04-06 N-(2-hydroxyethyl) pyrrolidine esters - with cell growth inhibiting activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES403631A ES403631A1 (en) 1972-06-08 1972-06-08 A method of obtaining two esters of N- (2-hydroxytyl) -pirrolidin. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES403631A1 true ES403631A1 (en) 1975-05-01

Family

ID=8461384

Family Applications (1)

Application Number Title Priority Date Filing Date
ES403631A Expired ES403631A1 (en) 1972-06-08 1972-06-08 A method of obtaining two esters of N- (2-hydroxytyl) -pirrolidin. (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
DE (1) DE2317219A1 (en)
ES (1) ES403631A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190133B (en) * 1986-06-19 1988-02-10 Chiesi Farma Spa VALPROIC ACID AND (E) -2-VALPROENOIC ACID DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS

Also Published As

Publication number Publication date
DE2317219A1 (en) 1974-01-03

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