ES405215A1 - Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas. - Google Patents
Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas.Info
- Publication number
- ES405215A1 ES405215A1 ES405215A ES405215A ES405215A1 ES 405215 A1 ES405215 A1 ES 405215A1 ES 405215 A ES405215 A ES 405215A ES 405215 A ES405215 A ES 405215A ES 405215 A1 ES405215 A1 ES 405215A1
- Authority
- ES
- Spain
- Prior art keywords
- substd
- opt
- cpds
- lower alkyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 piperazino Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- RAHZWNYVWXNFOC-UHFFFAOYSA-N Sulphur dioxide Chemical group O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 125000004659 aryl alkyl thio group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000005505 thiomorpholino group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712121950 DE2121950A1 (en) | 1971-05-04 | 1971-05-04 | Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES405215A1 true ES405215A1 (es) | 1975-07-16 |
Family
ID=5806805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES405215A Expired ES405215A1 (es) | 1971-05-04 | 1972-07-27 | Procedimiento para la preparacion de nuevas tieno (3,2-d) pirimidinas. |
Country Status (5)
| Country | Link |
|---|---|
| BG (1) | BG19166A3 (es) |
| DE (1) | DE2121950A1 (es) |
| ES (1) | ES405215A1 (es) |
| RO (1) | RO63551A (es) |
| ZA (1) | ZA723016B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5124333A (en) * | 1989-08-02 | 1992-06-23 | Ube Industries, Ltd. | Aminopyrimidine derivatives and harmful organisms preventive agent |
| PT882051E (pt) * | 1996-02-07 | 2002-04-29 | Janssen Pharmaceutica Nv | Tiofenopirimidinas |
| CN101163706A (zh) * | 2005-04-21 | 2008-04-16 | 贝林格尔·英格海姆国际有限公司 | 用于治疗炎性疾病的二氢噻吩并嘧啶 |
| EP1847543A1 (de) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
| CA2702518A1 (en) | 2007-10-19 | 2009-04-23 | Boehringer Ingelheim International Gmbh | New piperazino-dihydrothienopyrimidine derivatives |
| CA2702524A1 (en) | 2007-10-19 | 2009-04-23 | Boehringer Ingelheim International Gmbh | Heterocycle-substituted piperazino-dihydrothienopyrimidines |
| CN104069112A (zh) | 2007-10-19 | 2014-10-01 | 贝林格尔.英格海姆国际有限公司 | 取代的哌啶子基-二氢噻吩并嘧啶 |
| WO2011078143A1 (ja) * | 2009-12-22 | 2011-06-30 | 塩野義製薬株式会社 | ピリミジン誘導体およびそれらを含有する医薬組成物 |
| US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
| US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
| GB201410816D0 (en) * | 2014-06-17 | 2014-07-30 | Ucb Biopharma Sprl And Katholieke Universiteit Leuven | Therapeutic agents |
-
1971
- 1971-05-04 DE DE19712121950 patent/DE2121950A1/de active Pending
-
1972
- 1972-04-28 RO RO7200078212A patent/RO63551A/ro unknown
- 1972-05-03 ZA ZA723016A patent/ZA723016B/xx unknown
- 1972-05-03 BG BG021459A patent/BG19166A3/xx unknown
- 1972-07-27 ES ES405215A patent/ES405215A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2121950A1 (en) | 1972-11-23 |
| BG19166A3 (bg) | 1975-04-30 |
| ZA723016B (en) | 1974-01-30 |
| RO63551A (fr) | 1978-07-15 |
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