ES407332A1 - Water swellable polymers and their metal complexes - Google Patents

Water swellable polymers and their metal complexes

Info

Publication number
ES407332A1
ES407332A1 ES407332A ES407332A ES407332A1 ES 407332 A1 ES407332 A1 ES 407332A1 ES 407332 A ES407332 A ES 407332A ES 407332 A ES407332 A ES 407332A ES 407332 A1 ES407332 A1 ES 407332A1
Authority
ES
Spain
Prior art keywords
group
acid
iron
carbon atoms
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES407332A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE12613/71A external-priority patent/SE359447B/xx
Priority claimed from SE12614/71A external-priority patent/SE356754B/xx
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of ES407332A1 publication Critical patent/ES407332A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyethers (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)

Abstract

A process for the preparation of an aqueous iron-containing composition suitable for parenteral administration in human and veterinary medicine, which process is characterized in that a) a trivalent water-soluble iron compound and b) a physiologically safe water-swellable polymer, consisting of i) at least one hydroxycarboxylic acid selected from the group consisting of arabic acid, gluconic acid and glucoheptonic acid and salts and lactones derived therefrom; ii) at least one polyvalent alcohol selected from the group consisting of glycerin, polyglycerins, tetrites, pentites, hexites, hepptites, derivatives partially etherified with alcohol groups containing 1 to 5 carbon atoms of said polyhydric alcohols, and derivatives partially etherified with hydroxyalkyl groups containing 1 to 5 carbon atoms of said polyvalent alcohols; and iii) at least one polymerization agent selected from the group consisting of dihalohydrins and epihalohydrins and diepoxides derived therefrom, and mixtures thereof, are reacted in aqueous solution, after which the pH of the reaction mixture is adjusted by addition of alkali such that at the end of the reaction it is from about 10 to about 14, after which the iron-containing reaction product is precipitated and, if desired, further purified, possibly by repeated dissolution operations and precipitation and then, if desired after drying, is dissolved in water under sterile conditions. (Machine-translation by Google Translate, not legally binding)
ES407332A 1971-10-06 1975-03-31 Water swellable polymers and their metal complexes Expired ES407332A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE12613/71A SE359447B (en) 1971-10-06 1971-10-06
SE12614/71A SE356754B (en) 1971-10-06 1971-10-06

Publications (1)

Publication Number Publication Date
ES407332A1 true ES407332A1 (en) 1976-01-16

Family

ID=26655894

Family Applications (1)

Application Number Title Priority Date Filing Date
ES407332A Expired ES407332A1 (en) 1971-10-06 1975-03-31 Water swellable polymers and their metal complexes

Country Status (21)

Country Link
JP (1) JPS4861611A (en)
AR (1) AR199188A1 (en)
BE (1) BE789758A (en)
CA (1) CA991544A (en)
CH (1) CH590891A5 (en)
CS (1) CS178876B2 (en)
CY (1) CY917A (en)
DD (1) DD105722A5 (en)
DE (1) DE2247021C3 (en)
ES (1) ES407332A1 (en)
FI (1) FI49475C (en)
FR (1) FR2157831B1 (en)
GB (1) GB1411266A (en)
HU (2) HU164864B (en)
IE (2) IE37761B1 (en)
KE (1) KE2757A (en)
MY (1) MY7800008A (en)
NL (1) NL162943C (en)
NO (1) NO132521C (en)
SU (1) SU730276A3 (en)
TR (1) TR17725A (en)

Also Published As

Publication number Publication date
DE2247021C3 (en) 1979-08-16
AR199188A1 (en) 1974-08-14
JPS4861611A (en) 1973-08-29
HU165476B (en) 1974-09-28
FR2157831B1 (en) 1976-04-23
DE2247021B2 (en) 1978-12-14
IE37761B1 (en) 1977-10-12
NL162943B (en) 1980-02-15
CS178876B2 (en) 1977-10-31
HU164864B (en) 1974-05-28
NL7213482A (en) 1973-04-10
NO132521C (en) 1975-11-26
IE37761L (en) 1973-04-06
CH590891A5 (en) 1977-08-31
TR17725A (en) 1975-07-23
NO132521B (en) 1975-08-18
BE789758A (en) 1973-04-06
IE37760L (en) 1973-04-06
FI49475B (en) 1975-04-01
DD105722A5 (en) 1974-05-12
FR2157831A1 (en) 1973-06-08
FI49475C (en) 1975-07-10
SU730276A3 (en) 1980-04-25
GB1411266A (en) 1975-10-22
MY7800008A (en) 1978-12-31
DE2247021A1 (en) 1973-04-12
CY917A (en) 1977-12-23
IE37760B1 (en) 1977-10-12
KE2757A (en) 1977-10-14
NL162943C (en) 1980-07-15
CA991544A (en) 1976-06-22

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