ES408731A1 - A procedure for the preparation of acids 7-acilamido7-metoxi-3-cefem-4-carboxilicos and their steres. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of acids 7-acilamido7-metoxi-3-cefem-4-carboxilicos and their steres. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES408731A1 ES408731A1 ES408731A ES408731A ES408731A1 ES 408731 A1 ES408731 A1 ES 408731A1 ES 408731 A ES408731 A ES 408731A ES 408731 A ES408731 A ES 408731A ES 408731 A1 ES408731 A1 ES 408731A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- translation
- formula
- preparation
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the preparation of 7-acylamido-7-methoxy-3-cephem-4-carboxylic acids and their esters, of the formula: **(See formula)** where A is hydrogen, hydroxy, azido, halogen, carbamoyloxy, N-lower alkylcarbamoyloxy, N, N-dialkyl lower) -carbamoyloxy, a tertiary amine, lower alkoxy, acyloxy or heterocyclotium; R1 is hydrogen or trichlorethyl, tert-butyl, benzoylmethyl, p-methoxybenzyl, benzyl, benzohydryl, trimethylsilyl or methoxymethyl; R2 is hydrogen, halogen, amino, guanidino, phosphono, hydroxy, tetrazolyl, carboxy, sulfo or sulfamino and R3 is phenyl, substituted phenyl, a 5- or 6-membered monocyclic heterocycle containing one or more oxygen, sulfur or nitrogen atoms in the ring, substituted heterocycles, phenylthio, heterocycle or substituted heterocyclium or cyano, the method of which is to treat a compound of the formula: **(See formula)** where A, R1, R2 and R3 are as defined above, with an alumina base or silica gel as the isomerizing agent, and optionally, separating the ester group. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20058771A | 1971-11-19 | 1971-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES408731A1 true ES408731A1 (en) | 1976-03-16 |
Family
ID=22742338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES408731A Expired ES408731A1 (en) | 1971-11-19 | 1972-11-17 | A procedure for the preparation of acids 7-acilamido7-metoxi-3-cefem-4-carboxilicos and their steres. (Machine-translation by Google Translate, not legally binding) |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS4857992A (en) |
| AT (1) | AT321463B (en) |
| CS (1) | CS187364B2 (en) |
| ES (1) | ES408731A1 (en) |
| HU (1) | HU165581B (en) |
| PL (1) | PL84057B1 (en) |
| SU (1) | SU450413A3 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5417755B2 (en) * | 1973-11-26 | 1979-07-02 | ||
| JPS5442999B2 (en) * | 1973-12-18 | 1979-12-17 |
-
1972
- 1972-11-06 CS CS748572A patent/CS187364B2/en unknown
- 1972-11-07 PL PL15867472A patent/PL84057B1/pl unknown
- 1972-11-10 AT AT959572A patent/AT321463B/en not_active IP Right Cessation
- 1972-11-10 SU SU1845922A patent/SU450413A3/en active
- 1972-11-17 ES ES408731A patent/ES408731A1/en not_active Expired
- 1972-11-18 HU HUME001561 patent/HU165581B/hu unknown
- 1972-11-20 JP JP11574872A patent/JPS4857992A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PL84057B1 (en) | 1976-02-28 |
| JPS4857992A (en) | 1973-08-14 |
| AT321463B (en) | 1975-04-10 |
| HU165581B (en) | 1974-09-28 |
| SU450413A3 (en) | 1974-11-15 |
| CS187364B2 (en) | 1979-01-31 |
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