ES409042A1 - Procedure for the obtaining of new 3-substitute lower alkinylenamines. (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for the preparation of 3-substituted lower alkenylene amines of general formula i ** (see formula) ** Wherein ar means a monocyclic aromatic moiety or a monocyclic heterocyclic moiety of aromatic character, the alkylene group c n h 2 n separates the carbon atom from the nitrogen atom by 2 to 4 carbon atoms, n represents the number 2 to 7, and each of the radicals r and r'signify hydrogen or lower alkyl, their salts and carbonyl and amino derivatives, characterized in that a) a 3-ar-co- (pyrrole, pyridine, 1,4-dihydropyridine, azepine,, 5- or 6,7-dihydroazepine) corresponding to the general formula i, or a quaternary salt, or b) the ring of a compound of general formula iii or iv is closed ** (see formula) ** Or c) the compounds of general formula v or vi are condensed ** (see formula) ** Where one of the radicals x and y means hydrogen or a metal atom and the other a free or functionally modified carboxy group, or d) in a compound of general formula vii ** (see formula) ** Where z means iminomethylene or hydroxymethylene, the group z is transformed into the carbonyl group and, if desired, a compound obtained is transformed into another compound according to the present invention, or a compound obtained is transformed into its salts, carbonyl derivatives or amino, and/or, if desired, a salt obtained is transformed into the free compound, and/or, if desired, a mixture obtained from isomers or racemates is separated into the different isomers or racemates and/or, if desired, the obtained racemates dissociate in the optical antipodes. (Machine-translation by Google Translate, not legally binding)