ES410018A1 - Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation - Google Patents

Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation

Info

Publication number
ES410018A1
ES410018A1 ES410018A ES410018A ES410018A1 ES 410018 A1 ES410018 A1 ES 410018A1 ES 410018 A ES410018 A ES 410018A ES 410018 A ES410018 A ES 410018A ES 410018 A1 ES410018 A1 ES 410018A1
Authority
ES
Spain
Prior art keywords
group
benzoxazole
aromatic
carboxylic
aliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES410018A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Henkel AG and Co KGaA
Original Assignee
Henkel AG and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel AG and Co KGaA filed Critical Henkel AG and Co KGaA
Publication of ES410018A1 publication Critical patent/ES410018A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la obtención de ácido benzoxazol-2-carboxílico o bien sus derivados, de fórmula general**fórmula** en la que Me significa hidrógeno, un metal alcalino, un ión amónico o una base de nitrógeno orgánica, y los restos R1 a R4 significan, en caso dado, hidrógeno, halógeno, un grupo alquilo de cadena corta , un grupo alcoxi de cadena corta, un grupo nitro, un grupo carboxílico, un grupo carboxilato o un grupo carboxilamida, caracterizado porque un éster del ácido benzoxazol-2-carboxílico de fórmula general **fórmula** en la que R1 a R4 tienen los significados arriba indicado y R significa un resto hidrocarburo alifático, aromático, alifático-aromático o aromático-alifático, se saponifica con una base adecuada, para la obtención del ácido benzoxazol-2-carboxílico libre y de sus productos de sustitución en caso dado la mezcla de reacción de acidifica y la mezcla de reacción de la saponificación se elabora como tal , o bien después de acidificar , en la forma usual.Process for obtaining benzoxazole-2-carboxylic acid or its derivatives, of the general formula ** formula ** in which Me means hydrogen, an alkali metal, an ammonium ion or an organic nitrogen base, and the residues R1 a R4 means, if necessary, hydrogen, halogen, a short-chain alkyl group, a short-chain alkoxy group, a nitro group, a carboxylic group, a carboxylate group or a carboxylamide group, characterized in that an ester of benzoxazole-2 acid -carboxylic of general formula ** formula ** in which R1 to R4 have the meanings indicated above and R means an aliphatic, aromatic, aliphatic-aromatic or aromatic-aliphatic hydrocarbon residue, it is saponified with a suitable base, to obtain the Free benzoxazole-2-carboxylic acid and its substitution products, if appropriate, the reaction mixture is acidified and the saponification reaction mixture is worked up as such, or after acidification, in the usual way.

ES410018A 1971-12-27 1972-12-26 Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation Expired ES410018A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2164851A DE2164851A1 (en) 1971-12-27 1971-12-27 ANTI-INFLAMMATORS FOR COSMETIC PREPARATIONS

Publications (1)

Publication Number Publication Date
ES410018A1 true ES410018A1 (en) 1975-12-01

Family

ID=5829372

Family Applications (3)

Application Number Title Priority Date Filing Date
ES410019A Expired ES410019A1 (en) 1971-12-27 1972-12-26 Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation
ES410018A Expired ES410018A1 (en) 1971-12-27 1972-12-26 Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation
ES410017A Expired ES410017A1 (en) 1971-12-27 1972-12-26 Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES410019A Expired ES410019A1 (en) 1971-12-27 1972-12-26 Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES410017A Expired ES410017A1 (en) 1971-12-27 1972-12-26 Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation

Country Status (9)

Country Link
US (1) US3895022A (en)
JP (1) JPS4872340A (en)
BE (1) BE793341A (en)
BR (1) BR7209119D0 (en)
DE (1) DE2164851A1 (en)
ES (3) ES410019A1 (en)
FR (1) FR2165996B1 (en)
GB (1) GB1405776A (en)
NL (1) NL7216060A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4137235A (en) * 1974-07-01 1979-01-30 Eastman Kodak Company Oxazole esters and their use as stabilizers in organic compositions
GB2074561B (en) * 1980-03-19 1984-08-30 Hokko Chem Ind Co Benzoxazolone derivatives processes for preparation thereof and compositions containing them
US4298742A (en) * 1980-05-12 1981-11-03 Usv Pharmaceutical Corporation Esters of benzoxa(thia)zole-2-carboxylic acids
US4405633A (en) * 1982-03-01 1983-09-20 Usv Pharmaceutical Corporation Method of treatment of asthma
US4620010A (en) * 1984-03-29 1986-10-28 Usv Pharmaceutical Corp. Process for preparing carboalkoxy substituted benzoxazole compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641029A (en) * 1970-02-02 1972-02-08 American Cyanamid Co Substituted benzoxazolecarboxamides and benzothiazolecarboxamides

Also Published As

Publication number Publication date
NL7216060A (en) 1973-06-29
BR7209119D0 (en) 1973-11-01
BE793341A (en) 1973-06-27
DE2164851A1 (en) 1973-07-05
FR2165996A1 (en) 1973-08-10
GB1405776A (en) 1975-09-10
JPS4872340A (en) 1973-09-29
ES410019A1 (en) 1975-12-01
US3895022A (en) 1975-07-15
ES410017A1 (en) 1975-12-01
FR2165996B1 (en) 1975-11-28

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