ES411018A2 - Derivatives of 4,-aminomethyl-dibenzo-b,e- 11-oxepine-2,- spiro- 1,3, -dioxolane their method of preparation and their thera peutic application - Google Patents
Derivatives of 4,-aminomethyl-dibenzo-b,e- 11-oxepine-2,- spiro- 1,3, -dioxolane their method of preparation and their thera peutic applicationInfo
- Publication number
- ES411018A2 ES411018A2 ES411018A ES411018A ES411018A2 ES 411018 A2 ES411018 A2 ES 411018A2 ES 411018 A ES411018 A ES 411018A ES 411018 A ES411018 A ES 411018A ES 411018 A2 ES411018 A2 ES 411018A2
- Authority
- ES
- Spain
- Prior art keywords
- formula
- dibenzo
- spiro
- dioxolane
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical class [H]N([H])* 0.000 abstract 1
- 125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Improvements introduced in the object of the main patent No. 403,262 applied for on May 27, 1972 for: "A process for the preparation of new N-amino-tertiary-methyl-4'-dibenzo (b, e) oxepino-11-spiro-2' -dioxclanos-1', 3'''; according to which when the nitrogen atom belongs to a secondary amino group, said compounds being of the general formula ** (See formula) ** wherein R represents an alcohol group containing 1 to 4 carbon atoms, comprising condensing, in benzene medium, bromomethyl-4'-dibenzo- (b, e) -oxepin-11-spiro-2'-dioxolane-1', 3' of the formula ** (See formula) ** and a primary amine of the formula R-NH2 where R has the same meaning as in formula I. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7244842A FR2210390B2 (en) | 1972-12-15 | 1972-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES411018A2 true ES411018A2 (en) | 1977-07-01 |
Family
ID=9108796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES411018A Expired ES411018A2 (en) | 1972-12-15 | 1973-01-26 | Derivatives of 4,-aminomethyl-dibenzo-b,e- 11-oxepine-2,- spiro- 1,3, -dioxolane their method of preparation and their thera peutic application |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5336476B2 (en) |
| AU (1) | AU467009B2 (en) |
| BE (1) | BE794902A (en) |
| CA (1) | CA985291A (en) |
| CH (1) | CH558793A (en) |
| ES (1) | ES411018A2 (en) |
| FR (1) | FR2210390B2 (en) |
| GB (1) | GB1360367A (en) |
| IT (1) | IT1055523B (en) |
| LU (1) | LU66975A1 (en) |
| NL (1) | NL7301487A (en) |
| SE (1) | SE394890B (en) |
| ZA (1) | ZA73487B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53149771U (en) * | 1977-04-28 | 1978-11-25 |
-
0
- BE BE794902D patent/BE794902A/en unknown
-
1972
- 1972-12-15 FR FR7244842A patent/FR2210390B2/fr not_active Expired
-
1973
- 1973-01-19 GB GB287973A patent/GB1360367A/en not_active Expired
- 1973-01-23 ZA ZA730487A patent/ZA73487B/en unknown
- 1973-01-25 CH CH104573A patent/CH558793A/en not_active IP Right Cessation
- 1973-01-26 ES ES411018A patent/ES411018A2/en not_active Expired
- 1973-02-01 NL NL7301487A patent/NL7301487A/xx not_active Application Discontinuation
- 1973-02-02 JP JP1303273A patent/JPS5336476B2/ja not_active Expired
- 1973-02-05 IT IT67234/73A patent/IT1055523B/en active
- 1973-02-06 LU LU66975A patent/LU66975A1/xx unknown
- 1973-02-07 AU AU51888/73A patent/AU467009B2/en not_active Expired
- 1973-02-26 CA CA164,593A patent/CA985291A/en not_active Expired
- 1973-03-14 SE SE7303565A patent/SE394890B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7301487A (en) | 1974-06-18 |
| ZA73487B (en) | 1973-10-31 |
| CA985291A (en) | 1976-03-09 |
| CH558793A (en) | 1975-02-14 |
| AU5188873A (en) | 1974-08-08 |
| BE794902A (en) | 1973-08-02 |
| SE394890B (en) | 1977-07-18 |
| DE2304224A1 (en) | 1974-06-20 |
| JPS4987686A (en) | 1974-08-22 |
| DE2304224B2 (en) | 1977-04-21 |
| FR2210390B2 (en) | 1976-07-02 |
| LU66975A1 (en) | 1973-08-17 |
| FR2210390A2 (en) | 1974-07-12 |
| JPS5336476B2 (en) | 1978-10-03 |
| IT1055523B (en) | 1982-01-11 |
| GB1360367A (en) | 1974-07-17 |
| AU467009B2 (en) | 1975-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170704 |