ES413044A1 - Process for the preparation of cyanoalkyl substituted phenothiazi ne derivatives - Google Patents
Process for the preparation of cyanoalkyl substituted phenothiazi ne derivativesInfo
- Publication number
- ES413044A1 ES413044A1 ES413044A ES413044A ES413044A1 ES 413044 A1 ES413044 A1 ES 413044A1 ES 413044 A ES413044 A ES 413044A ES 413044 A ES413044 A ES 413044A ES 413044 A1 ES413044 A1 ES 413044A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen atom
- phenothiazi
- derivatives
- preparation
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 125000004966 cyanoalkyl group Chemical group 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 2
- QUPDWYMUPZLYJZ-UHFFFAOYSA-N ethyl Chemical compound C[CH2] QUPDWYMUPZLYJZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 229950000688 phenothiazine Drugs 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- -1 alkylthio radical Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Phenothiazine preparation procedure, of general formula: **(See formula)** where R represents a hydrogen atom or the methyl radical, represents a hydrogen atom or a methyl or ethyl radical and Y represents a hydrogen atom or an alkyl, alkyloxy or alkylthio radical containing 1 to 4 carbon atoms, characterized in that a nitrile of general formula is reacted: R1 - CH2 - CN wherein R1 represents a hydrogen atom or a methyl or ethyl radical, with a phenothiazine of general formula: **(See formula)** where Y and R are defined as above. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7210653A FR2178304A5 (en) | 1972-03-27 | 1972-03-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES413044A1 true ES413044A1 (en) | 1976-01-16 |
Family
ID=9095852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES413044A Expired ES413044A1 (en) | 1972-03-27 | 1973-03-27 | Process for the preparation of cyanoalkyl substituted phenothiazi ne derivatives |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS4992077A (en) |
| AR (1) | AR193943A1 (en) |
| AT (1) | AT322565B (en) |
| BE (1) | BE797352A (en) |
| CH (1) | CH557836A (en) |
| DE (1) | DE2315258A1 (en) |
| ES (1) | ES413044A1 (en) |
| FR (1) | FR2178304A5 (en) |
| GB (1) | GB1365847A (en) |
| HU (1) | HU165603B (en) |
| IL (1) | IL41884A0 (en) |
| NL (1) | NL7303834A (en) |
| SU (1) | SU457223A3 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2691459B1 (en) * | 1992-05-25 | 1995-06-09 | Adir | NOVEL PHENOTHIAZINE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
| US7071211B2 (en) | 2002-09-27 | 2006-07-04 | Bausch & Lomb Inc. | Small organic molecules that increase the activity of gelatinase a in ocular cells |
-
1972
- 1972-03-27 FR FR7210653A patent/FR2178304A5/fr not_active Expired
-
1973
- 1973-03-19 NL NL7303834A patent/NL7303834A/xx unknown
- 1973-03-26 HU HURO715A patent/HU165603B/hu unknown
- 1973-03-26 JP JP48033634A patent/JPS4992077A/ja active Pending
- 1973-03-26 IL IL41884A patent/IL41884A0/en unknown
- 1973-03-26 AR AR247236A patent/AR193943A1/en active
- 1973-03-26 CH CH436673A patent/CH557836A/en not_active IP Right Cessation
- 1973-03-26 BE BE129284A patent/BE797352A/en unknown
- 1973-03-26 GB GB1436073A patent/GB1365847A/en not_active Expired
- 1973-03-27 SU SU1895840A patent/SU457223A3/en active
- 1973-03-27 AT AT267373A patent/AT322565B/en not_active IP Right Cessation
- 1973-03-27 DE DE2315258A patent/DE2315258A1/en active Pending
- 1973-03-27 ES ES413044A patent/ES413044A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH557836A (en) | 1975-01-15 |
| BE797352A (en) | 1973-09-26 |
| AT322565B (en) | 1975-05-26 |
| FR2178304A5 (en) | 1973-11-09 |
| GB1365847A (en) | 1974-09-04 |
| AR193943A1 (en) | 1973-05-31 |
| SU457223A3 (en) | 1975-01-15 |
| HU165603B (en) | 1974-09-28 |
| JPS4992077A (en) | 1974-09-03 |
| DE2315258A1 (en) | 1973-10-11 |
| NL7303834A (en) | 1973-10-01 |
| IL41884A0 (en) | 1973-05-31 |
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