ES414653A1 - Procedimiento para la preparacion de 6 alfa-metil-9 alfa- fluor - 11 beta, 17 alfadihidroxi-pregna-1,4-dien-3,20-dio- na. - Google Patents

Procedimiento para la preparacion de 6 alfa-metil-9 alfa- fluor - 11 beta, 17 alfadihidroxi-pregna-1,4-dien-3,20-dio- na.

Info

Publication number: ES414653A1
Authority: ES; Spain
Prior art keywords: alpha; methyl; 11beta; 17alpha; dione
Prior art date: 1973-03-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES414653A

Other languages

English (en)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

FARMILA FARMA MILANO

Original Assignee

FARMILA FARMA MILANO

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-03-09

Filing date

1973-05-11

Publication date

1976-02-01

1973-05-11 Application filed by FARMILA FARMA MILANO filed Critical FARMILA FARMA MILANO

1976-02-01 Publication of ES414653A1 publication Critical patent/ES414653A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
230000002378 acidificating effect Effects 0.000 abstract 1
TZIHFWKZFHZASV-UHFFFAOYSA-N anhydrous methyl formate Natural products COC=O TZIHFWKZFHZASV-UHFFFAOYSA-N 0.000 abstract 1
229910052792 caesium Inorganic materials 0.000 abstract 1
TVFDJXOCXUVLDH-UHFFFAOYSA-N caesium atom Chemical compound [Cs] TVFDJXOCXUVLDH-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
WBJINCZRORDGAQ-UHFFFAOYSA-N formic acid ethyl ester Natural products CCOC=O WBJINCZRORDGAQ-UHFFFAOYSA-N 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
239000000376 reactant Substances 0.000 abstract 1
GKASDNZWUGIAMG-UHFFFAOYSA-N triethyl orthoformate Chemical compound CCOC(OCC)OCC GKASDNZWUGIAMG-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

ES414653A 1973-03-09 1973-05-11 Procedimiento para la preparacion de 6 alfa-metil-9 alfa- fluor - 11 beta, 17 alfadihidroxi-pregna-1,4-dien-3,20-dio- na. Expired ES414653A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT2234173A IT1056732B (it)	1973-03-09	1973-03-09	6 alfa metil 9 alfa flupro 11 beta idrossi derivati del 17alfa idrossi progresterone

Publications (1)

Publication Number	Publication Date
ES414653A1 true ES414653A1 (es)	1976-02-01

Family

ID=11194924

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES414653A Expired ES414653A1 (es)	1973-03-09	1973-05-11	Procedimiento para la preparacion de 6 alfa-metil-9 alfa- fluor - 11 beta, 17 alfadihidroxi-pregna-1,4-dien-3,20-dio- na.

Country Status (3)

Country	Link
ES (1)	ES414653A1 (es)
FR (1)	FR2223364A1 (es)
IT (1)	IT1056732B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2246359A1 (en)	2009-04-23	2010-11-03	Crystal Pharma, S.L.U.	Process for obtaining fluorometholone and intermediates therefor

1973
- 1973-03-09 IT IT2234173A patent/IT1056732B/it active
- 1973-05-11 ES ES414653A patent/ES414653A1/es not_active Expired
- 1973-05-30 FR FR7319766A patent/FR2223364A1/fr active Granted

Also Published As

Publication number	Publication date
FR2223364B1 (es)	1977-12-30
IT1056732B (it)	1982-02-20
FR2223364A1 (en)	1974-10-25

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