ES416728A2 - Glycoproteins - Google Patents
GlycoproteinsInfo
- Publication number
- ES416728A2 ES416728A2 ES416728A ES416728A ES416728A2 ES 416728 A2 ES416728 A2 ES 416728A2 ES 416728 A ES416728 A ES 416728A ES 416728 A ES416728 A ES 416728A ES 416728 A2 ES416728 A2 ES 416728A2
- Authority
- ES
- Spain
- Prior art keywords
- origin
- serum
- glycoproteins
- obtaining
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000003886 Glycoproteins Human genes 0.000 title abstract 4
- 108090000288 Glycoproteins Proteins 0.000 title abstract 4
- 210000002966 serum Anatomy 0.000 abstract 4
- 241001465754 Metazoa Species 0.000 abstract 2
- 238000011026 diafiltration Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000003169 placental effect Effects 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000000717 retained effect Effects 0.000 abstract 2
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 1
- PTHCMJGKKRQCBF-UHFFFAOYSA-N Cellulose, microcrystalline Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC)C(CO)O1 PTHCMJGKKRQCBF-UHFFFAOYSA-N 0.000 abstract 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 abstract 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 abstract 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract 1
- 235000011130 ammonium sulphate Nutrition 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000005227 gel permeation chromatography Methods 0.000 abstract 1
- 230000003603 histaminopectic effect Effects 0.000 abstract 1
- 229920000831 ionic polymer Polymers 0.000 abstract 1
- 238000001155 isoelectric focusing Methods 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 229940068041 phytic acid Drugs 0.000 abstract 1
- 235000002949 phytic acid Nutrition 0.000 abstract 1
- 239000000467 phytic acid Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4715—Pregnancy proteins, e.g. placenta proteins, alpha-feto-protein, pregnancy specific beta glycoprotein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Pregnancy & Childbirth (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gynecology & Obstetrics (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Improvements introduced in the object of the main patent No. 393,796, applied for on July 30, 1971, for: "A process for obtaining a glycoprotein of human serum origin", according to which a process for obtaining histaminopexic glycoproteins of human serum origin or animal, or of placental origin, of isoelectric point 4 ± 0.2 determined by electrofocusing, which have a concentration of at least 1,000,000 histaminepexic units per mg, is characterized by subjecting a serum of human or animal origin, or a serum of placental origin, to the action of ammonium sulfate, obtain a precipitate made up of proteins, put the precipitate back into an aqueous solution, then treat this solution with phytic acid, filter and subject the filtrate containing the glycoproteins to diafiltration on a selective porosity membrane based on non-ionic polymers, separate Protein fraction retained in the diafiltration cell, then subjected to purification by carboxymethyl cellulose gel chromatography at a pH of the order of 4.2, and separate the fraction not retained on the column. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7224890A FR2191888B2 (en) | 1972-07-10 | 1972-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES416728A2 true ES416728A2 (en) | 1977-10-16 |
Family
ID=9101595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES416728A Expired ES416728A2 (en) | 1972-07-10 | 1973-07-09 | Glycoproteins |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4942813A (en) |
| BE (1) | BE802100R (en) |
| CA (1) | CA997333A (en) |
| DE (1) | DE2335102A1 (en) |
| ES (1) | ES416728A2 (en) |
| FR (1) | FR2191888B2 (en) |
| GB (1) | GB1433365A (en) |
| HU (1) | HU168850B (en) |
| NL (1) | NL7309579A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1114943B (en) * | 1977-12-27 | 1986-02-03 | Sclavo Inst Sieroterapeut | HUMAN CHORIONIC SOMATOMAMMOTROPINE PREPARATION PROCESS |
-
1972
- 1972-07-10 FR FR7224890A patent/FR2191888B2/fr not_active Expired
-
1973
- 1973-07-09 NL NL7309579A patent/NL7309579A/xx unknown
- 1973-07-09 ES ES416728A patent/ES416728A2/en not_active Expired
- 1973-07-09 BE BE133280A patent/BE802100R/en active
- 1973-07-09 CA CA176,013A patent/CA997333A/en not_active Expired
- 1973-07-10 HU HURO738A patent/HU168850B/hu unknown
- 1973-07-10 GB GB3290073A patent/GB1433365A/en not_active Expired
- 1973-07-10 JP JP48077184A patent/JPS4942813A/ja active Pending
- 1973-07-10 DE DE19732335102 patent/DE2335102A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NL7309579A (en) | 1974-01-14 |
| JPS4942813A (en) | 1974-04-22 |
| FR2191888B2 (en) | 1975-08-08 |
| BE802100R (en) | 1974-01-09 |
| DE2335102A1 (en) | 1974-01-24 |
| GB1433365A (en) | 1976-04-28 |
| CA997333A (en) | 1976-09-21 |
| HU168850B (en) | 1976-07-28 |
| FR2191888A2 (en) | 1974-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170704 |