ES418996A1 - Un procedimiento para la preparacion de derivados de piri- midina biologicamente activos. - Google Patents

Un procedimiento para la preparacion de derivados de piri- midina biologicamente activos.

Info

Publication number: ES418996A1
Authority: ES; Spain
Prior art keywords: pyrimidino; thiazepine; oxazepine; azepine; dibenzo
Prior art date: 1972-09-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES418996A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Akzo NV

Original Assignee

Akzo NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-09-23

Filing date

1973-09-22

Publication date

1976-07-01

1973-09-22 Application filed by Akzo NV filed Critical Akzo NV

1976-07-01 Publication of ES418996A1 publication Critical patent/ES418996A1/es

Status Expired legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

ES418996A 1972-09-23 1973-09-22 Un procedimiento para la preparacion de derivados de piri- midina biologicamente activos. Expired ES418996A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NLAANVRAGE7212915,A NL176458C (nl)	1972-09-23	1972-09-23	Werkwijze ter bereiding van een farmaceutisch preparaat en werkwijze voor de bereiding van daartoe geschikte actieve stoffen.

Publications (1)

Publication Number	Publication Date
ES418996A1 true ES418996A1 (es)	1976-07-01

Family

ID=19816997

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES418996A Expired ES418996A1 (es)	1972-09-23	1973-09-22	Un procedimiento para la preparacion de derivados de piri- midina biologicamente activos.

Country Status (18)

Country	Link
US (1)	US3892695A (fr)
JP (1)	JPS5912678B2 (fr)
AR (1)	AR203090A1 (fr)
AU (1)	AU472312B2 (fr)
BE (1)	BE805178A (fr)
CA (1)	CA1019733A (fr)
CH (1)	CH592094A5 (fr)
DE (1)	DE2347727C2 (fr)
DK (1)	DK140668B (fr)
ES (1)	ES418996A1 (fr)
FI (1)	FI54311C (fr)
FR (1)	FR2199996B1 (fr)
GB (1)	GB1445765A (fr)
HU (1)	HU167206B (fr)
IE (1)	IE38221B1 (fr)
NL (1)	NL176458C (fr)
SE (1)	SE407686B (fr)
ZA (1)	ZA737131B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL179906C (nl) *	1974-02-09	1986-12-01	Akzo Nv	Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten.
US4217452A (en) *	1974-02-09	1980-08-12	Akzona Incorporated	Synthesis for the preparation of tetracyclic compounds
NL7414038A (nl) *	1974-10-28	1976-05-03	Akzo Nv	Nieuwe tetracyclische pyrrolidino derivaten.
GB1472382A (en) *	1975-01-16	1977-05-04	Wyeth John & Brother Ltd	Dibenzopyrimidoazepines
NL7610942A (nl) *	1976-10-02	1978-04-04	Akzo Nv	Werkwijze voor het bereiden van 1,4-diazepine derivaten.
NL7809726A (nl) *	1978-09-26	1980-03-28	Akzo Nv	Nieuwe tetracyclische verbindingen.
HU195491B (en) *	1985-12-20	1988-05-30	Egyt Gyogyszervegyeszeti Gyar	Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
CH678623A5 (en) *	1989-05-17	1991-10-15	Sochinaz Societe Chimique De V	Prepn. of di:benzo pyrazino azepine(s)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL154511B (nl) *	1967-07-07	1977-09-15	Organon Nv	Werkwijze ter bereiding van piperazinederivaten, werkwijze ter bereiding van een farmaceutisch preparaat, dat een dergelijke verbinding bevat en vormstukken bereid volgens deze werkwijze.
US3470181A (en) *	1967-10-23	1969-09-30	American Home Prod	Fused 2-pyrimidinepropionic acid compounds,related compounds,and the process for their preparation

1972
- 1972-09-23 NL NLAANVRAGE7212915,A patent/NL176458C/xx not_active IP Right Cessation
1973
- 1973-09-06 IE IE1587/73A patent/IE38221B1/xx unknown
- 1973-09-06 ZA ZA737131*A patent/ZA737131B/xx unknown
- 1973-09-07 US US396251A patent/US3892695A/en not_active Expired - Lifetime
- 1973-09-11 AU AU60197/73A patent/AU472312B2/en not_active Expired
- 1973-09-14 GB GB4331873A patent/GB1445765A/en not_active Expired
- 1973-09-17 DK DK507673AA patent/DK140668B/da not_active IP Right Cessation
- 1973-09-18 CA CA181,312A patent/CA1019733A/en not_active Expired
- 1973-09-20 AR AR250175A patent/AR203090A1/es active
- 1973-09-20 FR FR7333768A patent/FR2199996B1/fr not_active Expired
- 1973-09-21 FI FI2963/73A patent/FI54311C/fi active
- 1973-09-21 DE DE2347727A patent/DE2347727C2/de not_active Expired
- 1973-09-21 SE SE7312873A patent/SE407686B/sv unknown
- 1973-09-21 BE BE135926A patent/BE805178A/fr not_active IP Right Cessation
- 1973-09-21 HU HUAO373A patent/HU167206B/hu unknown
- 1973-09-21 JP JP48106809A patent/JPS5912678B2/ja not_active Expired
- 1973-09-21 CH CH1358173A patent/CH592094A5/xx not_active IP Right Cessation
- 1973-09-22 ES ES418996A patent/ES418996A1/es not_active Expired

Also Published As

Publication number	Publication date
NL176458B (nl)	1984-11-16
GB1445765A (en)	1976-08-11
CA1019733A (en)	1977-10-25
NL176458C (nl)	1985-04-16
JPS4985098A (fr)	1974-08-15
FI54311C (fi)	1978-11-10
HU167206B (fr)	1975-09-27
NL7212915A (fr)	1974-03-26
DK140668B (da)	1979-10-22
FR2199996B1 (fr)	1977-09-09
DE2347727A1 (de)	1974-04-04
JPS5912678B2 (ja)	1984-03-24
FR2199996A1 (fr)	1974-04-19
IE38221B1 (en)	1978-01-18
DE2347727C2 (de)	1986-12-11
CH592094A5 (fr)	1977-10-14
DK140668C (fr)	1980-03-24
AU6019773A (en)	1975-03-13
IE38221L (en)	1974-03-23
SE407686B (sv)	1979-04-09
AU472312B2 (en)	1976-05-20
BE805178A (fr)	1974-03-21
ZA737131B (en)	1974-08-28
US3892695A (en)	1975-07-01
FI54311B (fi)	1978-07-31
AR203090A1 (es)	1975-08-14

Legal Events

Date	Code	Title	Description
2007-11-01	FD1A	Patent lapsed	Effective date: 19880218

Publication	Publication Date	Title
ES385927A1 (es)	1973-12-01	Un procedimiento para la preparacion de nuevos derivados dexantona.
ES379913A1 (es)	1972-09-16	Procedimiento de preparacion de nuevos benzamidoetil pipe- racinas.
IL37825A0 (en)	1971-11-29	Derivatives of benzodiazepines
ES409436A1 (es)	1976-03-16	Un procedimiento para la preparacion de nuevos derivados deisoindolina.
ES415000A1 (es)	1976-06-01	Procedimiento para la preparacion de difenil-alea-noilami- nopiridinas.
ES416495A1 (es)	1976-06-01	Un procedimiento para la preparacion de nuevos derivados deacido quinaldico.
FR2277589B1 (fr)	1978-12-29
ES418526A1 (es)	1976-04-01	Procedimiento para la obtencion de colorantes reactivos concelulosa.
JPS568387A (en)	1981-01-28	Manufacture of novel diazepine derivative
FR2190851B1 (fr)	1977-07-29
ES421281A1 (es)	1976-04-16	Procedimiento para la produccion de penicilinas.
ES376149A1 (es)	1972-03-16	Procedimiento para la preparacion de derivados del boro.
IE38221L (en)	1974-03-23	Pyrimidinoheterocyclic compounds
ES432939A1 (es)	1976-11-01	Procedimiento de preparacion de nuevos azabicicloalcanos disustituidos.
ES417971A1 (es)	1976-06-01	Procedimiento para la obtencion de diabenzazecinas.
ES411969A1 (es)	1976-01-01	Procedimiento para la preparacion de una rifamicina 3-sus- tituida.
ES380906A1 (es)	1972-09-16	Procedimiento de preparacion de nuevos derivados tricicli- cos.
ES423950A1 (es)	1976-05-16	Procedimiento para la preparacion de 3 - carbetoxihidrazino- piridazinas - 6 - sustituidas.
ES421130A1 (es)	1976-06-16	Procedimiento para preparar derivados de ditiino (1,4) (2, 3-c) pirrol.
IL42947A0 (en)	1973-11-28	The preparation of benzodiazepine derivatives
ES418572A1 (es)	1976-04-16	Procedimiento para la preparacion de derivados de adenosinadisustituidos en n (6).
PH12351A (en)	1979-01-29	Novel derivatives of 6 alpha-methyl-prednisolone
IL40101A0 (en)	1972-10-29	The preparation of certain indolobenzazepine derivatives
CA918660A (en)	1973-01-09	Derivatives of benzodiazepines
ES443511A1 (es)	1977-08-16	Un procedimiento para la preparacion de acetal de 8,10 : diaza-1-formil-6-hidroxi-5-metilen-2-oxa-biclo (4,2,2) de- can-7,9-diona.