ES420201A1 - Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos. - Google Patents

Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.

Info

Publication number: ES420201A1
Authority: ES; Spain
Prior art keywords: carbon atoms; moiety; salts; formula; hydrocarbon residue
Prior art date: 1970-01-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES420201A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee

Ciba Geigy AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-01-08

Filing date

1973-11-02

Publication date

1976-03-16

1970-01-08 Priority claimed from CH20470A external-priority patent/CH554311A/de

1973-11-02 Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG

1976-03-16 Publication of ES420201A1 publication Critical patent/ES420201A1/es

Status Expired legal-status Critical Current

Links

HXKKHQJGJAFBHI-UHFFFAOYSA-N 1-aminopropan-2-ol Chemical class CC(O)CN HXKKHQJGJAFBHI-UHFFFAOYSA-N 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 10
150000003839 salts Chemical class 0.000 abstract 4
125000001931 aliphatic group Chemical group 0.000 abstract 3
229910052757 nitrogen Inorganic materials 0.000 abstract 3
125000004433 nitrogen atom Chemical group N* 0.000 abstract 3
125000001951 carbamoylamino group Chemical group C(N)(=O)N* 0.000 abstract 2
125000001183 hydrocarbyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
BQJBONTVMVGWPV-UHFFFAOYSA-N (2-hydroxyphenyl)urea Chemical compound NC(=O)NC1=CC=CC=C1O BQJBONTVMVGWPV-UHFFFAOYSA-N 0.000 abstract 1
MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
JMSJITMUOWILHF-UHFFFAOYSA-N [2-(3-amino-2-hydroxypropoxy)phenyl]urea Chemical class NCC(O)COC1=CC=CC=C1NC(N)=O JMSJITMUOWILHF-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000005133 alkynyloxy group Chemical group 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000003700 epoxy group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1
239000011593 sulfur Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES420201A 1970-01-08 1973-11-02 Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos. Expired ES420201A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH20470A CH554311A (de)	1970-01-08	1970-01-08	Verfahren zur herstellung neuer hydroxyamine.
CH1678870		1970-11-13

Publications (1)

Publication Number	Publication Date
ES420201A1 true ES420201A1 (es)	1976-03-16

Family

ID=25683866

Family Applications (6)

Application Number	Title	Priority Date	Filing Date
ES387059A Expired ES387059A1 (es)	1970-01-08	1971-01-07	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-o-aminopropanos.
ES420202A Expired ES420202A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propano.
ES420201A Expired ES420201A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.
ES420205A Expired ES420205A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.
ES420204A Expired ES420204A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.
ES420203A Expired ES420203A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES387059A Expired ES387059A1 (es)	1970-01-08	1971-01-07	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-o-aminopropanos.
ES420202A Expired ES420202A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propano.

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
ES420205A Expired ES420205A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.
ES420204A Expired ES420204A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.
ES420203A Expired ES420203A1 (es)	1970-01-08	1973-11-02	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-3-amino-propanos.

Country Status (15)

Country	Link
JP (3)	JPS5518700B1 (es)
AR (6)	AR204898A1 (es)
AT (3)	AT318649B (es)
BE (1)	BE761321A (es)
CA (1)	CA1149819A (es)
CS (6)	CS155959B2 (es)
DE (1)	DE2100323C3 (es)
DK (1)	DK129650B (es)
ES (6)	ES387059A1 (es)
FR (1)	FR2081419B1 (es)
GB (1)	GB1311044A (es)
HU (1)	HU168606B (es)
NL (1)	NL167685C (es)
PL (1)	PL92434B1 (es)
SE (1)	SE361308B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3935259A (en)	1970-01-08	1976-01-27	Ciba-Geigy Corporation	New amines and processes for their manufacture
US4038313A (en) *	1970-01-08	1977-07-26	Ciba-Geigy Corporation	Cycloalkylureido phenoxy propanolamines
JPS5614661B2 (es) *	1971-12-23	1981-04-06
AT321315B (de) *	1972-02-28	1975-03-25	Chemie Linz Ag	Verfahren zur Herstellung von neuen Ureidophenoxypropylaminderivaten und von deren Salzen
JPS5013356A (es) *	1973-06-08	1975-02-12
JPS5013357A (es) *	1973-06-08	1975-02-12
JPS53105452A (en) *	1978-02-25	1978-09-13	Dresden Arzneimittel	Method for production of derivative of ureidphenoxyyalkanolamine
JPS53105456A (en) *	1978-02-25	1978-09-13	Dresden Arzneimittel	Method for production of derivative of ureidphenoxyyalkanolamine
JPS53105454A (en) *	1978-02-25	1978-09-13	Dresden Arzneimittel	Method for production of derivative of ureidphenoxyyalkanolamine
US4177280A (en) *	1978-07-03	1979-12-04	Syntex (U.S.A.) Inc.	Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS61178357U (es) *	1985-04-24	1986-11-07
JPS63147473U (es) *	1987-03-16	1988-09-28
JPS649170U (es) *	1988-07-15	1989-01-18
DE202012101380U1 (de)	2012-04-16	2012-06-15	Fernsteuergeräte Kurt Oelsch GmbH	Seillängengeber

1970
- 1970-12-23 CA CA000101368A patent/CA1149819A/en not_active Expired
- 1970-12-30 JP JP12313970A patent/JPS5518700B1/ja active Pending
1971
- 1971-01-01 AR AR238166A patent/AR204898A1/es active
- 1971-01-01 AR AR238164A patent/AR204685A1/es active
- 1971-01-01 AR AR238168A patent/AR203984A1/es active
- 1971-01-01 AR AR238165A patent/AR207306A1/es active
- 1971-01-01 AR AR238167A patent/AR207307A1/es active
- 1971-01-05 DE DE2100323A patent/DE2100323C3/de not_active Expired
- 1971-01-05 FR FR7100076A patent/FR2081419B1/fr not_active Expired
- 1971-01-07 HU HUCI1073A patent/HU168606B/hu unknown
- 1971-01-07 AT AT922872A patent/AT318649B/de not_active IP Right Cessation
- 1971-01-07 NL NL7100178A patent/NL167685C/xx not_active IP Right Cessation
- 1971-01-07 AR AR233351A patent/AR194708A1/es active
- 1971-01-07 CS CS161572A patent/CS155959B2/cs unknown
- 1971-01-07 GB GB79371A patent/GB1311044A/en not_active Expired
- 1971-01-07 PL PL1971178941A patent/PL92434B1/pl unknown
- 1971-01-07 AT AT8271A patent/AT318647B/de not_active IP Right Cessation
- 1971-01-07 CS CS9871*#A patent/CS155958B2/cs unknown
- 1971-01-07 CS CS161672A patent/CS155960B2/cs unknown
- 1971-01-07 AT AT922972A patent/AT318650B/de not_active IP Right Cessation
- 1971-01-07 CS CS161772A patent/CS155961B2/cs unknown
- 1971-01-07 BE BE761321A patent/BE761321A/xx not_active IP Right Cessation
- 1971-01-07 CS CS161972A patent/CS155963B2/cs unknown
- 1971-01-07 CS CS161872A patent/CS155962B2/cs unknown
- 1971-01-07 DK DK4771AA patent/DK129650B/da unknown
- 1971-01-07 SE SE00101/71A patent/SE361308B/xx unknown
- 1971-01-07 ES ES387059A patent/ES387059A1/es not_active Expired
1973
- 1973-11-02 ES ES420202A patent/ES420202A1/es not_active Expired
- 1973-11-02 ES ES420201A patent/ES420201A1/es not_active Expired
- 1973-11-02 ES ES420205A patent/ES420205A1/es not_active Expired
- 1973-11-02 ES ES420204A patent/ES420204A1/es not_active Expired
- 1973-11-02 ES ES420203A patent/ES420203A1/es not_active Expired
1975
- 1975-06-07 JP JP6904975A patent/JPS563862B1/ja active Pending
1980
- 1980-06-05 JP JP7499780A patent/JPS5632305B1/ja active Pending

Also Published As

Publication number	Publication date
CS155959B2 (es)	1974-06-24
CA1149819A (en)	1983-07-12
CS155958B2 (es)	1974-06-24
DE2100323B2 (de)	1978-06-29
GB1311044A (en)	1973-03-21
DE2100323C3 (de)	1979-02-22
DK129650C (es)	1975-04-01
CS155962B2 (es)	1974-06-24
AR204898A1 (es)	1976-03-19
AR207306A1 (es)	1976-09-30
AT318650B (de)	1974-11-11
AR203984A1 (es)	1975-11-12
AR207307A1 (es)	1976-09-30
NL167685C (nl)	1982-01-18
ES420204A1 (es)	1976-03-01
AT318649B (de)	1974-11-11
JPS5632305B1 (es)	1981-07-27
FR2081419B1 (es)	1974-08-30
DE2100323A1 (de)	1972-06-15
JPS563862B1 (es)	1981-01-27
PL92434B1 (en)	1977-04-30
ES420202A1 (es)	1976-03-16
JPS5518700B1 (es)	1980-05-21
DK129650B (da)	1974-11-04
HU168606B (es)	1976-06-28
FR2081419A1 (es)	1971-12-03
NL7100178A (es)	1971-07-12
AR194708A1 (es)	1973-08-14
NL167685B (nl)	1981-08-17
ES387059A1 (es)	1974-07-01
BE761321A (fr)	1971-07-07
ES420203A1 (es)	1976-03-01
AR204685A1 (es)	1976-02-27
AT318647B (de)	1974-11-11
ES420205A1 (es)	1976-03-01
SE361308B (es)	1973-10-29
CS155963B2 (es)	1974-06-24
CS155961B2 (es)	1974-06-24
CS155960B2 (es)	1974-06-24

Publication	Publication Date	Title
ES387059A1 (es)	1974-07-01	Procedimiento para la obtencion de nuevos 1-(ureidofenoxi)-2-hidroxi-o-aminopropanos.
GB1514870A (en)	1978-06-21	Imidazolyloxime ethers having antimycotic and bactericidal activity
ES382014A1 (es)	1973-06-16	Procedimiento para la preparacion de 1-fenoxi-2-hidroxi - - 3 - cicloalcohilaminopropanos racemicos u opticamente ac- tivados y sus sales por adicion de acido.
ES462422A1 (es)	1978-10-01	Procedimiento para la preparacion de compuestos derivados den-alquil-sulfo-noxi-acetil-anilinas.
MY100206A (en)	1990-04-10	Certain substituted 3-amino-2-benzoylcyclohex-2- enones
ES387834A1 (es)	1973-06-01	Procedimiento para la preparacion de amidas de acido de vi-tamina a.
ES440029A1 (es)	1977-02-16	Un procedimiento para preparar nuevos derivados de 2-ami- noindano.
GB1008849A (en)	1965-11-03	Basically substituted triazolidines, processes for their manufacture and pharmaceutical preparations containing them
ES483985A1 (es)	1980-04-16	Procedimiento para preparar alfa-aril-alfa,alfa-bis(omega- (amino disustituido)alquil)acetamidas
ES402478A1 (es)	1975-04-01	Procedimiento para preparar derivados de alcanolamina.
ES455731A1 (es)	1978-01-01	Procedimiento para la preparacion de benzamidas disustitui- das en las posiciones 2 y 5.
ES469455A1 (es)	1978-12-01	Procedimiento para la produccion de o-propiloximas sustitui-das con restos basicos.
ES396174A1 (es)	1974-04-01	Procedimiento para la preparacion de compuestos derivados de aminoetanol.
ES556048A0 (es)	1988-02-16	Un procedimiento para la preparacion de un derivado de tiazolidina.
ES398427A1 (es)	1975-06-16	Un procedimiento para preparar 3-amido-1,2,4-triazoles.
ES376874A1 (es)	1972-05-16	Procedimiento para la preparacion de nuevos fenilcarbamatossustituidos.
ES425868A1 (es)	1976-06-01	Procedimiento para la preparacion de n-alquilcarbonatos fenil-substituidos.
ES423745A1 (es)	1976-04-16	Procedimiento para preparar derivados de 2-aminoindano.
ES435422A1 (es)	1976-12-01	Procedimiento para preparar composiciones fungicidas.
ES393554A1 (es)	1974-11-16	Un procedimiento para la preparacion de derivados de tia- zol.
NL7202150A (es)	1972-08-22
ES423746A1 (es)	1976-05-01	Procedimiento para preparar derivados de 2-aminoindano.
GB1028099A (en)	1966-05-04	Substituted propionanilides
ES400823A1 (es)	1975-11-01	Procedimiento para la preparacion de nuevos esteres de oxa-diazolilo.
ES409336A1 (es)	1976-04-16	La preparacion de nuevas fenilformamidinas.