ES427583A1 - Procedimiento para la obtencion de un derivado de la pira- zinoisoquinolina. - Google Patents
Procedimiento para la obtencion de un derivado de la pira- zinoisoquinolina.Info
- Publication number
- ES427583A1 ES427583A1 ES427583A ES427583A ES427583A1 ES 427583 A1 ES427583 A1 ES 427583A1 ES 427583 A ES427583 A ES 427583A ES 427583 A ES427583 A ES 427583A ES 427583 A1 ES427583 A1 ES 427583A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrazinoisoquinolines
- anthelmintic agents
- pyrazino
- hexahydro
- cyclization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940124339 anthelmintic agent Drugs 0.000 title 1
- 239000000921 anthelmintic agent Substances 0.000 title 1
- CCSONKKTCMHYFI-UHFFFAOYSA-N pyrido[3,4-f]quinoxaline Chemical class C1=NC=C2C3=NC=CN=C3C=CC2=C1 CCSONKKTCMHYFI-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000012467 final product Substances 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- GTRDOUXISKJZGL-UHFFFAOYSA-N 1,2,3,6,7,11b-hexahydropyrazino[2,1-a]isoquinolin-4-one Chemical compound C1=CC=C2C3CNCC(=O)N3CCC2=C1 GTRDOUXISKJZGL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 238000006480 benzoylation reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2331713A DE2331713A1 (de) | 1973-06-22 | 1973-06-22 | Pyrazinoisochinolin-derivat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES427583A1 true ES427583A1 (es) | 1976-11-16 |
Family
ID=5884721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES427583A Expired ES427583A1 (es) | 1973-06-22 | 1974-06-22 | Procedimiento para la obtencion de un derivado de la pira- zinoisoquinolina. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3993760A (es) |
| JP (1) | JPS5036497A (es) |
| AU (1) | AU474590B2 (es) |
| BE (1) | BE816607A (es) |
| CH (2) | CH601297A5 (es) |
| DE (1) | DE2331713A1 (es) |
| DK (1) | DK137388C (es) |
| EG (1) | EG14680A (es) |
| ES (1) | ES427583A1 (es) |
| FR (1) | FR2234005B1 (es) |
| GB (1) | GB1417359A (es) |
| HU (1) | HU170191B (es) |
| IL (1) | IL44831A (es) |
| NL (1) | NL7408395A (es) |
| ZA (1) | ZA743084B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2508947C3 (de) * | 1975-03-01 | 1982-02-25 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur Herstellung von 4-Oxo-1,2,3,6,7, 11b-hexahydro-4H-pyrazino [2,1-a] isochinolinen |
| IN157936B (es) * | 1982-07-08 | 1986-07-26 | Korea Advanced Inst Sci & Tech | |
| AU7285487A (en) * | 1986-04-07 | 1987-11-09 | Upjohn Company, The | Anthelmintic quaternaryalkyl acylhydrazones, method of use and compositions |
| AU2015349033B2 (en) * | 2014-11-21 | 2020-01-02 | Merck Patent Gmbh | Method for the production of praziquantel and precursors thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470062A1 (de) * | 1964-02-06 | 1969-05-08 | E Merck Ag Fa | Verfahren zur Herstellung von 1,2,3,6,7,11 b-Hexahydro-4 H-pyrazino-[2,1-a]-isochinolinen |
-
1973
- 1973-06-22 DE DE2331713A patent/DE2331713A1/de not_active Withdrawn
-
1974
- 1974-05-14 ZA ZA00743084A patent/ZA743084B/xx unknown
- 1974-05-15 IL IL44831A patent/IL44831A/en unknown
- 1974-06-07 GB GB2533774A patent/GB1417359A/en not_active Expired
- 1974-06-07 CH CH999277A patent/CH601297A5/xx not_active IP Right Cessation
- 1974-06-07 CH CH781974A patent/CH602725A5/xx not_active IP Right Cessation
- 1974-06-18 AU AU70156/74A patent/AU474590B2/en not_active Expired
- 1974-06-19 JP JP49070782A patent/JPS5036497A/ja active Pending
- 1974-06-20 HU HUME1746A patent/HU170191B/hu unknown
- 1974-06-20 BE BE145661A patent/BE816607A/xx unknown
- 1974-06-21 DK DK334274A patent/DK137388C/da active
- 1974-06-21 US US05/481,792 patent/US3993760A/en not_active Expired - Lifetime
- 1974-06-21 NL NL7408395A patent/NL7408395A/xx not_active Application Discontinuation
- 1974-06-22 ES ES427583A patent/ES427583A1/es not_active Expired
- 1974-06-22 EG EG235/74A patent/EG14680A/xx active
- 1974-06-24 FR FR7421811A patent/FR2234005B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EG14680A (en) | 1984-09-30 |
| AU7015674A (en) | 1975-12-18 |
| US3993760A (en) | 1976-11-23 |
| FR2234005A1 (es) | 1975-01-17 |
| AU474590B2 (en) | 1976-07-29 |
| HU170191B (es) | 1977-04-28 |
| GB1417359A (en) | 1975-12-10 |
| DE2331713A1 (de) | 1975-01-23 |
| NL7408395A (es) | 1974-12-24 |
| IL44831A0 (en) | 1974-07-31 |
| CH601297A5 (es) | 1978-07-14 |
| DK137388B (da) | 1978-02-27 |
| FR2234005B1 (es) | 1978-03-24 |
| ZA743084B (en) | 1975-05-28 |
| BE816607A (fr) | 1974-12-20 |
| DK334274A (es) | 1975-02-17 |
| DK137388C (da) | 1978-08-07 |
| IL44831A (en) | 1977-02-28 |
| JPS5036497A (es) | 1975-04-05 |
| CH602725A5 (es) | 1978-07-31 |
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