ES431015A1 - Procedimiento para la produccion de compuestos de 4-(m-bro-mofenil)-pirazodiazepina. - Google Patents

Procedimiento para la produccion de compuestos de 4-(m-bro-mofenil)-pirazodiazepina.

Info

Publication number: ES431015A1
Authority: ES; Spain
Prior art keywords: pyrazolodiazepine; methyl; formula; production; methods
Prior art date: 1972-12-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES431015A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Parke Davis and Co LLC

Original Assignee

Parke Davis and Co LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-12-15

Filing date

1974-10-15

Publication date

1976-11-01

1974-10-15 Application filed by Parke Davis and Co LLC filed Critical Parke Davis and Co LLC

1976-11-01 Publication of ES431015A1 publication Critical patent/ES431015A1/es

Status Expired legal-status Critical Current

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
XYEVREOOMFVLLS-UHFFFAOYSA-N pyrazolo[4,3-c]diazepine Chemical class C1=CC=NN=C2C=NN=C21 XYEVREOOMFVLLS-UHFFFAOYSA-N 0.000 title 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
CJWDJYGMXPYEDT-UHFFFAOYSA-N BrC=1C=C(C=CC=1)N1NC=CC=C2C1=CN=N2 Chemical class BrC=1C=C(C=CC=1)N1NC=CC=C2C1=CN=N2 CJWDJYGMXPYEDT-UHFFFAOYSA-N 0.000 abstract 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
239000012458 free base Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
-1 pyrazolodiazepine compound Chemical class 0.000 abstract 1
YPNVIBVEFVRZPJ-UHFFFAOYSA-L silver sulfate Chemical compound [Ag+].[Ag+].[O-]S([O-])(=O)=O YPNVIBVEFVRZPJ-UHFFFAOYSA-L 0.000 abstract 1
229910000367 silver sulfate Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES431015A 1972-12-15 1974-10-15 Procedimiento para la produccion de compuestos de 4-(m-bro-mofenil)-pirazodiazepina. Expired ES431015A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US00315631A US3823157A (en)	1972-12-15	1972-12-15	Pyrazolodiazepine compounds and methods for their production

Publications (1)

Publication Number	Publication Date
ES431015A1 true ES431015A1 (es)	1976-11-01

Family

ID=23225332

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
ES421427A Expired ES421427A1 (es)	1972-12-15	1973-12-13	Procedimiento para la produccion de compuestos de pirazolo-diazepina.
ES431015A Expired ES431015A1 (es)	1972-12-15	1974-10-15	Procedimiento para la produccion de compuestos de 4-(m-bro-mofenil)-pirazodiazepina.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ES421427A Expired ES421427A1 (es)	1972-12-15	1973-12-13	Procedimiento para la produccion de compuestos de pirazolo-diazepina.

Country Status (22)

Country	Link
US (1)	US3823157A (es)
JP (1)	JPS5732072B2 (es)
AR (2)	AR200295A1 (es)
AT (1)	AT338794B (es)
AU (1)	AU472275B2 (es)
BE (1)	BE808599A (es)
CA (1)	CA1023356A (es)
CH (2)	CH590284A5 (es)
DE (1)	DE2362034A1 (es)
DK (1)	DK138020B (es)
ES (2)	ES421427A1 (es)
FI (1)	FI54803C (es)
FR (1)	FR2210403B1 (es)
GB (1)	GB1399230A (es)
HU (1)	HU166758B (es)
IE (1)	IE38641B1 (es)
IL (1)	IL43865A (es)
NL (1)	NL165743C (es)
NO (1)	NO140670C (es)
PH (1)	PH12257A (es)
SE (2)	SE410604B (es)
ZA (1)	ZA737696B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2549686A1 (de) *	1974-11-06	1976-05-13	Parke Davis & Co	4-aryl-1,6-dihydro-trimethylimidazoeckige klammer auf 1,2-a eckige klammer zu pyrazolo eckige klammer auf 4,3-f eckige klammer zu eckige klammer auf 1,4 eckige klammer zu diazepin-verbindungen und verfahren zu deren herstellung
AT361486B (de) *	1975-08-07	1981-03-10	Hoffmann La Roche	Verfahren zur herstellung von neuen imidazo(1,5 -a) (1,4)diazepinverbindungen, ihren salzen und optisch aktiven formen
US4105851A (en) *	1975-09-08	1978-08-08	Parke, Davis & Company	1,3,8-Trimethylimidazopyrazolodiazepine compounds
US4349475A (en) *	1978-05-15	1982-09-14	Hoffmann-La Roche Inc.	Process for producing imidazodiazepines
US4376075A (en) *	1978-05-15	1983-03-08	Hoffmann-La Roche Inc.	Process for producing imidazodiazepines
US4349477A (en) *	1978-05-15	1982-09-14	Hoffmann-La Roche Inc.	Process for producing imidazodiazepines
US4377523A (en) *	1978-05-15	1983-03-22	Hoffmann-La Roche Inc.	Imidazodiazepines and processes therefor
US4349476A (en) *	1978-05-15	1982-09-14	Hoffmann-La Roche Inc.	Process for producing imidazodiazepines
JPS5961073U (ja) *	1982-10-18	1984-04-21	株式会社タカラ	盤ゲ−ム具
JPH0394280U (es) *	1990-01-12	1991-09-26
RU2186772C2 (ru) *	1999-11-11	2002-08-10	Иркутский институт химии СО РАН	Производные 1-метил-5-хлорпиразола и способ их получения

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3558605A (en) *	1969-05-14	1971-01-26	Parke Davis & Co	Pyrazolo(3,4-e)(1,4)diazepin-7-(1h)-one compounds

1972
- 1972-12-15 US US00315631A patent/US3823157A/en not_active Expired - Lifetime
1973
- 1973-10-01 ZA ZA00737696A patent/ZA737696B/xx unknown
- 1973-12-10 PH PH15310A patent/PH12257A/en unknown
- 1973-12-13 AU AU63584/73A patent/AU472275B2/en not_active Expired
- 1973-12-13 AT AT1043473A patent/AT338794B/de not_active IP Right Cessation
- 1973-12-13 CA CA188,152A patent/CA1023356A/en not_active Expired
- 1973-12-13 ES ES421427A patent/ES421427A1/es not_active Expired
- 1973-12-13 DE DE2362034A patent/DE2362034A1/de not_active Withdrawn
- 1973-12-13 NO NO4758/73A patent/NO140670C/no unknown
- 1973-12-13 FR FR7344548A patent/FR2210403B1/fr not_active Expired
- 1973-12-13 AR AR251494A patent/AR200295A1/es active
- 1973-12-13 IE IE2260/73A patent/IE38641B1/xx unknown
- 1973-12-13 CH CH1747173A patent/CH590284A5/xx not_active IP Right Cessation
- 1973-12-13 JP JP13825273A patent/JPS5732072B2/ja not_active Expired
- 1973-12-13 BE BE138836A patent/BE808599A/xx unknown
- 1973-12-13 CH CH1391376A patent/CH591489A5/xx not_active IP Right Cessation
- 1973-12-13 NL NL7317113.A patent/NL165743C/xx not_active IP Right Cessation
- 1973-12-13 HU HUPA1180A patent/HU166758B/hu unknown
- 1973-12-13 GB GB5792673A patent/GB1399230A/en not_active Expired
- 1973-12-13 FI FI3833/73A patent/FI54803C/fi active
- 1973-12-13 SE SE7316843A patent/SE410604B/xx unknown
- 1973-12-13 DK DK676673AA patent/DK138020B/da unknown
- 1973-12-20 IL IL43865A patent/IL43865A/en unknown
1974
- 1974-01-01 AR AR256062A patent/AR204106A1/es active
- 1974-10-15 ES ES431015A patent/ES431015A1/es not_active Expired
1976
- 1976-10-08 SE SE7611202A patent/SE410605B/xx unknown

Also Published As

Publication number	Publication date
FR2210403B1 (es)	1976-08-13
AU472275B2 (en)	1976-05-20
HU166758B (es)	1975-05-28
IE38641L (en)	1974-06-15
IE38641B1 (en)	1978-04-26
ZA737696B (en)	1975-05-28
NO140670B (no)	1979-07-09
DE2362034A1 (de)	1974-06-20
NL165743B (nl)	1980-12-15
AT338794B (de)	1977-09-12
DK138020B (da)	1978-06-26
IL43865A0 (en)	1974-03-14
GB1399230A (en)	1975-06-25
CH590284A5 (es)	1977-07-29
US3823157A (en)	1974-07-09
NL7317113A (es)	1974-06-18
SE410604B (sv)	1979-10-22
PH12257A (en)	1978-12-12
SE7611202L (sv)	1976-10-08
NO140670C (no)	1979-10-17
DK138020C (es)	1978-12-18
CA1023356A (en)	1977-12-27
FR2210403A1 (es)	1974-07-12
IL43865A (en)	1976-11-30
CH591489A5 (es)	1977-09-30
FI54803C (fi)	1979-03-12
AR204106A1 (es)	1975-11-20
BE808599A (fr)	1974-03-29
ATA1043473A (de)	1977-01-15
AR200295A1 (es)	1974-10-31
JPS4987695A (es)	1974-08-22
SE410605B (sv)	1979-10-22
ES421427A1 (es)	1976-12-01
AU6358473A (en)	1975-06-19
JPS5732072B2 (es)	1982-07-08
NL165743C (nl)	1981-05-15
FI54803B (fi)	1978-11-30

Publication	Publication Date	Title
ES421427A1 (es)	1976-12-01	Procedimiento para la produccion de compuestos de pirazolo-diazepina.
ES428295A1 (es)	1976-07-16	Procedimiento para la obtencion de derivados de canfeno sulfonados.
ES418036A1 (es)	1976-03-01	Procedimiento de preparacion de nuevos compuestos de quina-zolina.
ES421067A1 (es)	1976-04-01	Procedimiento para la preparacion de nuevas 2-fenilamino- imidazolinas sustituidas.
ES419016A1 (es)	1976-07-16	Procedimiento para la produccion de compuesto del acido 13-bromo - lisergico.
ES408730A1 (es)	1976-03-01	Un procedimiento de preparacion de nuevas 1,3-diamino gua- nidinas sustituidas.
ES419450A1 (es)	1976-07-01	Un procedimiento mejorado de aminacion con intercambio parala preparacion de 2-hidrazinobenzotiazoles.
ES402263A1 (es)	1976-01-01	Un metodo para sintetizar nuevos analogos de prostaglandi- na.
ES380355A1 (es)	1973-04-16	Un procedimiento para la preparacion de 4-pirazolidinoles 1,2-disustituidos.
ES446187A1 (es)	1977-10-01	Un metodo de preparar nuevos compuestos de oxima-eter.
ES451091A1 (es)	1977-12-01	Procedimiento para la produccion del compuesto s 11743na en forma de acido.
ES428011A1 (es)	1976-07-16	Procedimiento para la preparacion de 2-amino-3,5-dibromo- bencilamina.
ES442988A1 (es)	1977-04-16	Un procedimiento de preparacion de nuevos compuestos de sul-fenamida.
ES420666A1 (es)	1976-09-01	Procedimiento para preparar derivados de acidos (1-metil-5-nitro-2-imidazolil)tioalcanoicos.
ES393828A1 (es)	1973-08-16	Un metodo para la produccion de derivados de benzodiazepina.
ES397454A1 (es)	1974-06-01	Un procedimiento para la preparacion de derivados de tetra-hidro-isoquinolina.
ES309686A1 (es)	1966-01-16	Procedimiento para la producciën de nuevos compuestos de guanidinas
ES408079A1 (es)	1975-11-01	Procedimiento de obtencion de un nuevo derivado de cisteinagc-5.
ES419656A1 (es)	1976-03-16	Un procedimiento para la produccion de un compuesto de un ester alilaminoalcanolico.
ES417729A1 (es)	1977-01-01	Procedimiento para la preparacion de nuevos aminoetanoles.
ES390235A1 (es)	1973-07-01	Procedimiento para la preparacion de derivados de penicili-na.
ES412886A1 (es)	1976-05-01	Un procedimiento de preparacion de derivados de acidos tia-zolcarboxilicos.
ES421304A1 (es)	1976-04-01	Procedimiento de obtencion de derivados de fenil hidroxie- til aminas.
ES377139A1 (es)	1972-05-16	Un metodo de preparar una sal de pirrilviniltiazolio.
ES420471A1 (es)	1977-04-01	Un procedimiento para la produccion de derivados sustituidosde acido fenoxi-alfa-metilpropionico.