ES431265A1 - Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos. - Google Patents

Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos.

Info

Publication number
ES431265A1
ES431265A1 ES431265A ES431265A ES431265A1 ES 431265 A1 ES431265 A1 ES 431265A1 ES 431265 A ES431265 A ES 431265A ES 431265 A ES431265 A ES 431265A ES 431265 A1 ES431265 A1 ES 431265A1
Authority
ES
Spain
Prior art keywords
group
carbon atoms
alcohol
halogen
alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES431265A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19722210620 external-priority patent/DE2210620C2/de
Priority claimed from DE19722260620 external-priority patent/DE2260620A1/de
Priority claimed from DE19722260444 external-priority patent/DE2260444A1/de
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES431265A1 publication Critical patent/ES431265A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ES431265A 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos. Expired ES431265A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR157273X 1935-11-15
DE19722210620 DE2210620C2 (de) 1972-03-06 1972-03-06 Bis-Phenoxypropanolamine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE19722260620 DE2260620A1 (de) 1972-12-11 1972-12-11 Messerturbomuehle
DE19722260444 DE2260444A1 (de) 1972-12-11 1972-12-11 Neue bis-alkanol-aminderivate, deren saeureadditionssalze, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ES431265A1 true ES431265A1 (es) 1976-10-16

Family

ID=27431439

Family Applications (7)

Application Number Title Priority Date Filing Date
ES412333A Expired ES412333A1 (es) 1935-11-15 1973-03-05 Procedimiento para la preparacion de nuevos n,n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)- alfa, omega - iamino-alcanos recemicos u opticamente activos.
ES431262A Expired ES431262A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.
ES431261A Expired ES431261A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.
ES431264A Expired ES431264A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxisustituido-2-hidroxi-1-propil)-alfa, omega-diaminoal- canos racemicos u opticamente activos.
ES431265A Expired ES431265A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos.
ES431266A Expired ES431266A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos.
ES431263A Expired ES431263A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES412333A Expired ES412333A1 (es) 1935-11-15 1973-03-05 Procedimiento para la preparacion de nuevos n,n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)- alfa, omega - iamino-alcanos recemicos u opticamente activos.
ES431262A Expired ES431262A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.
ES431261A Expired ES431261A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.
ES431264A Expired ES431264A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxisustituido-2-hidroxi-1-propil)-alfa, omega-diaminoal- canos racemicos u opticamente activos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES431266A Expired ES431266A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n, n'-bis-(3- fenoxi sustituido-2-hidroxi-1-propil)-alfa,omega-diaminoal- canos racemicos u opticamente activos.
ES431263A Expired ES431263A1 (es) 1935-11-15 1974-10-23 Procedimiento para la preparacion de nuevos n,n'-bis-(3-fe- noxi sustituido-2-hidroxi-1-propil)-alfa, w-diaminoalcanos racemicos u opticamente activos.

Country Status (12)

Country Link
US (1) US3888898A (es)
JP (1) JPS5825657B2 (es)
AT (5) AT323131B (es)
CH (7) CH605634A5 (es)
DK (1) DK141660C (es)
ES (7) ES412333A1 (es)
FI (1) FI59391C (es)
FR (1) FR2175055B1 (es)
GB (1) GB1431341A (es)
NL (1) NL7303097A (es)
NO (1) NO137049C (es)
SE (1) SE413402B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975539A (en) * 1935-11-15 1976-08-17 Boehringer Ingelheim Gmbh Pharmaceutical compositions containing an N,N-bis-(3-phenoxy-2-hydroxy-propyl)-alkylenediamine and method of use
US4024281A (en) * 1972-05-26 1977-05-17 Smithkline Corporation N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines
US4041074A (en) * 1973-07-19 1977-08-09 Imperial Chemical Industries Limited 1-Hydroxyaryl-2-amidoalkylaminoethanol derivatives
US4029783A (en) * 1973-08-03 1977-06-14 Boehringer Mannheim G.M.B.H. N-substituted 1-amino-3-phenoxy-propan-2-ol compounds and therapeutic compositions containing them
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
US4041075A (en) * 1973-12-12 1977-08-09 Imperial Chemical Industries Limited Phenoxy-alkanolamine derivatives
US4139623A (en) * 1974-05-14 1979-02-13 C-G Corp. Cyclic-substituted derivatives of 1-amino-2-propanol
DE2555921C2 (de) * 1974-12-24 1983-01-20 Rohm and Haas Co., 19105 Philadelphia, Pa. Mehrzweckzusatzmischung für Benzin und eine sie enthaltende Kraftstoffmischung
US4013777A (en) * 1975-08-22 1977-03-22 Smithkline Corporation Bis-phenoxypropanolamines
FR2330383A1 (fr) * 1975-11-06 1977-06-03 Synthelabo Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment
IE47053B1 (en) * 1977-05-23 1983-12-14 Ici Ltd Cardiac stimulants
US4163053A (en) * 1977-12-27 1979-07-31 Schering Corporation Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
US4351848A (en) * 1978-03-16 1982-09-28 Drug Science Foundation 1-((1-Methylethyl)amino)-3-(((4-alkylthio)1-naphthalenyl)oxy)-2-propanol
EP0025111B1 (en) * 1979-08-10 1984-07-25 Sandoz Ag 3-aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
US4342783A (en) * 1980-06-30 1982-08-03 Synthelabo Anti-glaucoma agent
US4945182A (en) * 1985-12-24 1990-07-31 Merck & Co., Inc. Oculoselective beta-blockers
US4751278A (en) * 1987-04-29 1988-06-14 Ciba-Geigy Corporation Adducts of monoepoxides and selected diamines
US6001824A (en) * 1988-02-08 1999-12-14 The Trustees Of Columbia University Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
WO1989007098A1 (en) * 1988-02-08 1989-08-10 The Trustees Of Columbia University In The City Of Butyrl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
JP3356289B2 (ja) * 1995-06-26 2002-12-16 コンキャット リミティド 第一遷移系列元素に対してキレート化親和性および選択性のある化合物とその医療および診断への使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
DE1901549B2 (de) * 1968-09-30 1978-04-13 Veb Fahlberg-List, Chemische Und Pharmazeutische Fabriken, Ddr 3011 Magdeburg N,N'-Bis-[3-(2'-äthoxyphenoxy)-2-hydroxypropyl] -ethylendiamin, Verfahren zu dessen Herstellung und Arzneimittel auf dessen Basis
BE754604A (fr) * 1969-08-08 1971-02-08 Boehringer Sohn Ingelheim Le 1-(2-nitrilophenoxy)-2-hydroxy-3-ethyl-aminopropane et ses sels

Also Published As

Publication number Publication date
JPS48103532A (es) 1973-12-25
US3888898A (en) 1975-06-10
FR2175055A1 (es) 1973-10-19
CH605631A5 (es) 1978-10-13
DK141660B (da) 1980-05-19
NO137049C (no) 1977-12-21
ES431261A1 (es) 1977-02-01
GB1431341A (en) 1976-04-07
ES412333A1 (es) 1976-01-01
ES431264A1 (es) 1976-10-16
ATA157273A (de) 1975-02-15
AU5294473A (en) 1974-09-12
CH599924A5 (es) 1978-06-15
AT325023B (de) 1975-09-25
DK141660C (da) 1980-10-20
CH601182A5 (es) 1978-06-30
FI59391C (fi) 1981-08-10
ES431262A1 (es) 1977-02-01
AT323132B (de) 1975-06-25
CH605633A5 (es) 1978-10-13
FR2175055B1 (es) 1976-08-13
NO137049B (no) 1977-09-12
ES431263A1 (es) 1977-02-01
FI59391B (fi) 1981-04-30
ES431266A1 (es) 1976-10-16
AT323131B (de) 1975-06-25
AT326107B (de) 1975-11-25
JPS5825657B2 (ja) 1983-05-28
SE413402B (sv) 1980-05-27
CH605630A5 (es) 1978-10-13
CH605632A5 (es) 1978-10-13
AT325022B (de) 1975-09-25
CH605634A5 (es) 1978-10-13
NL7303097A (es) 1973-09-10

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