ES432038A2 - Imidazole derivatives - Google Patents

Imidazole derivatives

Info

Publication number
ES432038A2
ES432038A2 ES432038A ES432038A ES432038A2 ES 432038 A2 ES432038 A2 ES 432038A2 ES 432038 A ES432038 A ES 432038A ES 432038 A ES432038 A ES 432038A ES 432038 A2 ES432038 A2 ES 432038A2
Authority
ES
Spain
Prior art keywords
general formula
alcoholylthio
alcoholic
see formula
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES432038A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of ES432038A2 publication Critical patent/ES432038A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Improvements introduced in the object of the main patent No. 409,368, applied for on December 6, 1972, for "A process for the preparation of imidazole compounds", according to which for the compounds corresponding to the general formula **(See formula)** where X is oxygen or sulfur, R3 is alcoholylthio, alkenylthio, aralkohylthio, alkoxyalkoxy or alcoholylthio-alcohol, optionally R4 is alcoholic or cycloalkyl, and R1 and R2 are each alcoholic, alkenyl, alkoxyalkoyl or haloalcohyl, or R1 and R2, together with the nitrogen atom to which they are attached, form an optionally substituted heterocyclic ring selected from morpholino, thiamorpholino, 1-pyrrolidinyl and 1-piperidino, the method comprises reacting a compound of the general formula Y-NR1R2 with a compound of the general formula **(See formula)** in which R1, R2, R3 and R4 have the values given above, and (a) one of the groups Y and Q is hydrogen and the other is -CXZ in which X has the values given above and Z is halogen, or (b) Y is hydrogen and Q is the group **(See formula)** (Machine-translation by Google Translate, not legally binding)
ES432038A 1973-11-19 1974-11-18 Imidazole derivatives Expired ES432038A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB53621/73A GB1486192A (en) 1973-11-19 1973-11-19 Imidazole derivatives

Publications (1)

Publication Number Publication Date
ES432038A2 true ES432038A2 (en) 1977-03-16

Family

ID=10468443

Family Applications (1)

Application Number Title Priority Date Filing Date
ES432038A Expired ES432038A2 (en) 1973-11-19 1974-11-18 Imidazole derivatives

Country Status (18)

Country Link
JP (1) JPS50111237A (en)
AT (1) AT343405B (en)
BE (1) BE822343R (en)
CA (1) CA1064490A (en)
CS (1) CS183769B2 (en)
DE (1) DE2454795A1 (en)
DK (1) DK587174A (en)
ES (1) ES432038A2 (en)
FR (1) FR2251558B2 (en)
GB (1) GB1486192A (en)
HU (1) HU170942B (en)
IE (1) IE40417B1 (en)
IL (1) IL46070A (en)
IT (1) IT1046330B (en)
LU (1) LU71302A1 (en)
NL (1) NL7415038A (en)
SU (1) SU670195A3 (en)
ZA (1) ZA747286B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5235551A (en) * 1975-09-13 1977-03-18 Fujitsu Ltd Vote sale/subtraction/refund terminal equipment
US4226876A (en) * 1976-12-20 1980-10-07 Burroughs Wellcome Co. Arthropodicidal imidazoline derivatives
ZA787351B (en) * 1978-06-19 1980-08-27 Wellcome Found Imidazolines,their preparation,intermediates therefor,and pesticidal formulations and use of the imidazolines
US4996221A (en) * 1987-01-13 1991-02-26 The Board Of Trustees Of The Leland Stanford Junior University Histamine derivatives as immune modulators
WO1993014753A1 (en) * 1992-01-27 1993-08-05 The Board Of Trustees Of The Leland Stanford Junior University Histamine derivatives and methods for their use

Also Published As

Publication number Publication date
SU670195A3 (en) 1979-06-25
CA1064490A (en) 1979-10-16
AU7543674A (en) 1976-05-20
DK587174A (en) 1975-07-21
FR2251558B2 (en) 1978-06-16
IE40417L (en) 1975-05-19
ZA747286B (en) 1975-11-26
IE40417B1 (en) 1979-05-23
JPS50111237A (en) 1975-09-01
IL46070A (en) 1979-10-31
LU71302A1 (en) 1975-05-28
DE2454795A1 (en) 1975-05-28
IT1046330B (en) 1980-06-30
BE822343R (en) 1975-05-20
HU170942B (en) 1977-10-28
CS183769B2 (en) 1978-07-31
AT343405B (en) 1978-05-26
ATA923674A (en) 1977-09-15
FR2251558A2 (en) 1975-06-13
NL7415038A (en) 1975-05-21
GB1486192A (en) 1977-09-21

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Legal Events

Date Code Title Description
FD2A Announcement of lapse in spain

Effective date: 20170705