ES433593A1 - A PROCEDURE FOR PREPARING DERIVATIVES OF 1, 4-DIOXIDE DEQUINOXALIN-2-CARBOXAMIDE. - Google Patents

A PROCEDURE FOR PREPARING DERIVATIVES OF 1, 4-DIOXIDE DEQUINOXALIN-2-CARBOXAMIDE.

Info

Publication number
ES433593A1
ES433593A1 ES433593A ES433593A ES433593A1 ES 433593 A1 ES433593 A1 ES 433593A1 ES 433593 A ES433593 A ES 433593A ES 433593 A ES433593 A ES 433593A ES 433593 A1 ES433593 A1 ES 433593A1
Authority
ES
Spain
Prior art keywords
formula
carboxamide
see formula
procedure
dioxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES433593A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES433593A1 publication Critical patent/ES433593A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/137Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/12Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A procedure for preparing derivatives of quinoxalin-2-carboxamide 1,4-dioxide bearing a cyano group of the formula: ** (See formula) ** and the acid addition salts thereof; wherein the cyano substituent is at the 6-position or at the 7-position and R1 and R2 are each hydrogen, alkyl having one to four carbon atoms, 2-hydroxyethyl, 3-hydroxypropyl, CH2CH2NR3R4 or CH2CH2CH2NB3R4; wherein R3 and R4 are each alkyl having one to three carbon atoms; characterized by reacting a compound of the formula ** (See formula) ** with a compound of the formula ** (See formula) ** where M is (see formula), where R1 and R2 are as defined above, O-OR5 is the residue of an ester or an enamine thereof, and when R5 is the residue of an ester, react the product obtained with an amine of the formula ** (See formula) ** at a later stage and, if desired, prepare the pharmaceutically acceptable salts thereof. (Machine-translation by Google Translate, not legally binding)
ES433593A 1974-01-07 1975-01-04 A PROCEDURE FOR PREPARING DERIVATIVES OF 1, 4-DIOXIDE DEQUINOXALIN-2-CARBOXAMIDE. Expired ES433593A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43117074A 1974-01-07 1974-01-07

Publications (1)

Publication Number Publication Date
ES433593A1 true ES433593A1 (en) 1977-02-16

Family

ID=23710775

Family Applications (1)

Application Number Title Priority Date Filing Date
ES433593A Expired ES433593A1 (en) 1974-01-07 1975-01-04 A PROCEDURE FOR PREPARING DERIVATIVES OF 1, 4-DIOXIDE DEQUINOXALIN-2-CARBOXAMIDE.

Country Status (23)

Country Link
JP (1) JPS6011034B2 (en)
AR (1) AR203585A1 (en)
AT (1) AT347467B (en)
BE (1) BE824065A (en)
BG (1) BG25990A3 (en)
CA (1) CA1033739A (en)
CH (1) CH602670A5 (en)
CS (1) CS191253B2 (en)
DD (1) DD116825A1 (en)
DE (1) DE2500447A1 (en)
DK (1) DK140838C (en)
ES (1) ES433593A1 (en)
FI (1) FI59998C (en)
FR (1) FR2256758B1 (en)
GB (2) GB1453678A (en)
HU (1) HU170490B (en)
IE (1) IE40469B1 (en)
IT (1) IT1047758B (en)
LU (1) LU71601A1 (en)
NL (1) NL7500097A (en)
RO (1) RO76604A (en)
SU (1) SU633478A3 (en)
YU (1) YU36512B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5352255B2 (en) * 2009-01-28 2013-11-27 日本エンバイロケミカルズ株式会社 Quinoxaline compound or salt thereof, and industrial bactericidal composition

Also Published As

Publication number Publication date
SU633478A3 (en) 1978-11-15
AU7691074A (en) 1976-07-01
HU170490B (en) 1977-06-28
YU775A (en) 1982-02-25
BG25990A3 (en) 1979-01-12
IE40469L (en) 1975-07-07
FI59998B (en) 1981-07-31
CA1033739A (en) 1978-06-27
NL7500097A (en) 1975-07-09
IT1047758B (en) 1980-10-20
CS191253B2 (en) 1979-06-29
CH602670A5 (en) 1978-07-31
DD116825A1 (en) 1975-12-12
IE40469B1 (en) 1979-06-06
LU71601A1 (en) 1975-12-09
RO76604A (en) 1981-04-30
GB1453678A (en) 1976-10-27
FI59998C (en) 1981-11-10
JPS6011034B2 (en) 1985-03-22
FR2256758B1 (en) 1979-05-04
FI750017A7 (en) 1975-07-08
FR2256758A1 (en) 1975-08-01
GB1453677A (en) 1976-10-27
JPS50105678A (en) 1975-08-20
AT347467B (en) 1978-12-27
DE2500447A1 (en) 1975-07-17
ATA7475A (en) 1978-05-15
DK140838C (en) 1980-04-21
DK140838B (en) 1979-11-26
YU36512B (en) 1984-02-29
AR203585A1 (en) 1975-09-22
BE824065A (en) 1975-07-03
DK1775A (en) 1975-08-25

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