ES434323A1 - Un metodo para la preparacion de nuevos derivados de d, l- tirosina. - Google Patents

Un metodo para la preparacion de nuevos derivados de d, l- tirosina.

Info

Publication number: ES434323A1
Authority: ES; Spain
Prior art keywords: tertiary amino; tyrosil; benzoyl; amides; alkyl
Prior art date: 1974-02-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES434323A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Rottapharm SpA

Original Assignee

Rotta Research Laboratorium SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-02-01

Filing date

1975-01-31

Publication date

1976-12-16

1975-01-31 Application filed by Rotta Research Laboratorium SpA filed Critical Rotta Research Laboratorium SpA

1976-12-16 Publication of ES434323A1 publication Critical patent/ES434323A1/es

Status Expired legal-status Critical Current

Links

150000001408 amides Chemical class 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000001302 tertiary amino group Chemical group 0.000 abstract 2
150000003667 tyrosine derivatives Chemical class 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000001691 aryl alkyl amino group Chemical group 0.000 abstract 1
125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
-1 di-substituted phenyl Chemical group 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000467 secondary amino group Chemical group [H]N([*:1])[*:2] 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ES434323A 1974-02-01 1975-01-31 Un metodo para la preparacion de nuevos derivados de d, l- tirosina. Expired ES434323A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT67286/74A IT1062206B (it)	1974-02-01	1974-02-01	Derivati della tirosina attivi sulla muscolatura liscia

Publications (1)

Publication Number	Publication Date
ES434323A1 true ES434323A1 (es)	1976-12-16

Family

ID=11301149

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES434323A Expired ES434323A1 (es)	1974-02-01	1975-01-31	Un metodo para la preparacion de nuevos derivados de d, l- tirosina.

Country Status (19)

Country	Link
US (1)	US4004008A (fr)
JP (2)	JPS5417729B2 (fr)
AT (2)	AT342026B (fr)
BE (1)	BE824995A (fr)
CA (2)	CA1047498A (fr)
CH (2)	CH605657A5 (fr)
DE (1)	DE2503992C2 (fr)
ES (1)	ES434323A1 (fr)
FI (2)	FI63744C (fr)
FR (1)	FR2259592B1 (fr)
GB (1)	GB1467927A (fr)
HK (1)	HK38979A (fr)
HU (2)	HU174825B (fr)
IN (1)	IN139364B (fr)
IT (1)	IT1062206B (fr)
NL (1)	NL167683C (fr)
NO (2)	NO144210C (fr)
SE (2)	SE413094B (fr)
ZA (1)	ZA75530B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5225243A (en) *	1975-08-20	1977-02-25	Toshiba Electric Equip Corp	Distributing panel
US4579866A (en) *	1984-05-29	1986-04-01	Usv Pharmaceutical Corp.	Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
CA1320734C (fr) *	1986-02-04	1993-07-27	Suntory Limited	Derive pyrrolidineamide d'acide acylamine; composition pharmaceutique a base de ce derive
US5198458A (en) *	1986-02-04	1993-03-30	Suntory Limited	Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
IL99537A (en) *	1990-09-27	1995-11-27	Merck & Co Inc	Fibrinogen receptor antagonists and pharmaceutical compositions containing them
NZ239846A (en) *	1990-09-27	1994-11-25	Merck & Co Inc	Sulphonamide derivatives and pharmaceutical compositions thereof
US5258407A (en) *	1991-12-31	1993-11-02	Sterling Winthrop Inc.	3,4-disubstituted phenols-immunomodulating agents
US5206373A (en) *	1992-02-28	1993-04-27	Merck & Co., Inc.	Process for preparing fibrinogen receptor antagonists
DE10204951A1 (de) *	2002-02-06	2003-08-14	Basf Ag	Phenylalaninderivate als Herbizide
KR20060123344A (ko) *	2003-12-19	2006-12-01	바스프 악티엔게젤샤프트	벤조일-치환된 페닐알라닌아미드
CN101267813A (zh) *	2005-07-19	2008-09-17	第一三共株式会社	取代丙酰胺衍生物和含有其的药物组合物
WO2011094890A1 (fr) *	2010-02-02	2011-08-11	Argusina Inc.	Dérivés phénylalanines et leur utilisation comme modulateurs non peptidiques du récepteur de glp-1
WO2011156655A2 (fr)	2010-06-09	2011-12-15	Receptos, Inc.	Nouveaux stabilisants et modulateurs de récepteur glp-1
JP6007417B2 (ja)	2011-05-31	2016-10-12	レセプトスエルエルシー	新規ｇｌｐ−１受容体安定剤および調節剤
CN104080767A (zh)	2011-12-12	2014-10-01	瑞塞普托斯公司	新的glp-1受体调节剂
CN102659619A (zh) *	2012-04-18	2012-09-12	上海骏捷生化科技有限公司	一种合成酪氨酸衍生物的方法
CN103508921B (zh) *	2012-06-21	2015-09-30	贵州百灵企业集团制药股份有限公司	一种苯丙氨醇化合物的制备方法
CN103508920B (zh) *	2012-06-21	2016-03-02	贵州百灵企业集团制药股份有限公司	一种苯丙氨醇化合物的光学异构体的制备方法及其用途
JP6573604B2 (ja)	2013-06-11	2019-09-11	セルジーンインターナショナルツーエスエーアールエル	新規なｇｌｐ−１レセプターモジュレーター
CN107074820B (zh)	2014-07-25	2021-05-18	赛尔基因第二国际有限公司	Glp-1受体调节剂
CA2969944A1 (fr)	2014-12-10	2016-06-16	Celgene International Ii Sarl	Nouveaux modulateurs du recepteur du glp-1
CN107417560B (zh) *	2017-03-30	2020-05-22	上海常丰生物医药科技有限公司	一种合成盐酸替罗酰胺的方法
CN110015978B (zh) *	2019-04-29	2021-03-19	康化（上海）新药研发有限公司	O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法
CN115850107B (zh) *	2022-11-30	2024-11-12	苏州诚和医药化学有限公司	一种工业化合成盐酸替罗酰胺的方法

1974
- 1974-02-01 IT IT67286/74A patent/IT1062206B/it active Protection Beyond IP Right Term
1975
- 1975-01-22 GB GB287875A patent/GB1467927A/en not_active Expired
- 1975-01-24 ZA ZA00750530A patent/ZA75530B/xx unknown
- 1975-01-29 IN IN179/CAL/75A patent/IN139364B/en unknown
- 1975-01-30 FI FI750256A patent/FI63744C/fi not_active IP Right Cessation
- 1975-01-30 CH CH110875A patent/CH605657A5/xx not_active IP Right Cessation
- 1975-01-30 CA CA219,027A patent/CA1047498A/fr not_active Expired
- 1975-01-30 NO NO750287A patent/NO144210C/no unknown
- 1975-01-30 FI FI750255A patent/FI61479C/fi not_active IP Right Cessation
- 1975-01-30 BE BE152889A patent/BE824995A/fr not_active IP Right Cessation
- 1975-01-30 NO NO750288A patent/NO144211C/no unknown
- 1975-01-30 CA CA75219028A patent/CA1048503A/fr not_active Expired
- 1975-01-30 CH CH110975A patent/CH605658A5/xx not_active IP Right Cessation
- 1975-01-31 DE DE2503992A patent/DE2503992C2/de not_active Expired
- 1975-01-31 SE SE7501115A patent/SE413094B/xx unknown
- 1975-01-31 HU HU75RO820A patent/HU174825B/hu unknown
- 1975-01-31 HU HU75RO821A patent/HU175156B/hu unknown
- 1975-01-31 AT AT74575A patent/AT342026B/de not_active IP Right Cessation
- 1975-01-31 JP JP1328575A patent/JPS5417729B2/ja not_active Expired
- 1975-01-31 NL NL7501193A patent/NL167683C/xx not_active IP Right Cessation
- 1975-01-31 AT AT74675A patent/AT343632B/de not_active IP Right Cessation
- 1975-01-31 ES ES434323A patent/ES434323A1/es not_active Expired
- 1975-01-31 SE SE7501114A patent/SE410850B/xx not_active IP Right Cessation
- 1975-01-31 JP JP1326675A patent/JPS5417728B2/ja not_active Expired
- 1975-01-31 FR FR7503079A patent/FR2259592B1/fr not_active Expired
- 1975-02-03 US US05/546,481 patent/US4004008A/en not_active Expired - Lifetime
1979
- 1979-06-14 HK HK389/79A patent/HK38979A/xx unknown

Also Published As

Publication number	Publication date
SE7501115L (sv)	1975-08-04
JPS50116442A (fr)	1975-09-11
ATA74675A (de)	1977-10-15
FI61479B (fi)	1982-04-30
NO750288L (fr)	1975-08-25
CH605658A5 (fr)	1978-10-13
CH605657A5 (fr)	1978-10-13
FI61479C (fi)	1982-08-10
HU175156B (hu)	1980-05-28
NL167683B (nl)	1981-08-17
BE824995A (fr)	1975-05-15
AT342026B (de)	1978-03-10
NL167683C (nl)	1982-01-18
NO144211B (no)	1981-04-06
DE2503992C2 (de)	1982-01-21
ZA75530B (en)	1976-01-28
SE410850B (sv)	1979-11-12
DE2503992A1 (de)	1975-08-14
SE413094B (sv)	1980-04-14
FI63744B (fi)	1983-04-29
AT343632B (de)	1978-06-12
NO144210B (no)	1981-04-06
FI63744C (fi)	1983-08-10
FI750255A7 (fr)	1975-08-02
FR2259592A1 (fr)	1975-08-29
JPS50116441A (fr)	1975-09-11
GB1467927A (en)	1977-03-23
NL7501193A (nl)	1975-08-05
NO144211C (no)	1981-07-15
ATA74575A (de)	1977-07-15
US4004008A (en)	1977-01-18
AU7775075A (en)	1976-08-05
HU174825B (hu)	1980-03-28
SE7501114L (sv)	1975-08-04
NO750287L (fr)	1975-08-25
NO144210C (no)	1981-07-15
CA1048503A (fr)	1979-02-13
IN139364B (fr)	1976-06-12
IT1062206B (it)	1983-09-20
FR2259592B1 (fr)	1978-07-21
CA1047498A (fr)	1979-01-30
JPS5417728B2 (fr)	1979-07-02
JPS5417729B2 (fr)	1979-07-02
HK38979A (en)	1979-06-22
FI750256A7 (fr)	1975-08-02

Publication	Publication Date	Title
SE7501114L (sv)	1975-08-04	Forfarande for framstellning av d.l-tyrosinderivat med farmaceutisk aktivitet pa glatt muskulatur.
ES467288A1 (es)	1978-10-16	Un procedimiento para la preparacion de nuevas n-(aminoal- cohil sustituido)-2-oxo-1-pirrolidinacetamidas.
ES8103735A1 (es)	1981-03-16	Procedimiento para la preparacion de derivados de pipreridi-na
ES8104321A1 (es)	1981-04-01	Procedimiento para separar un derivado de alquil-cetohexopi-ranosida
GR3006139T3 (fr)	1993-06-21
IE40511B1 (en)	1979-06-20	N-(1-(-phenylalkyl)-piperidyl-j)-(-(-pyridyl)-carbonic acid amides
DE3069813D1 (en)	1985-01-31	Pharmaceutical composition containing a diphenylhydantoin derivative, derivatives used and their preparation
BG104445A (en)	2001-02-28	NOVEL 3,6-HEMIKETALS FROM THE CLASS OF 9a-AZALIDES
ES8507090A1 (es)	1985-09-16	Procedimiento para la obtencion de nuevas 1, 5-benzotiacepinas
SE7605361L (sv)	1976-11-17	Sett att framstella nya n-substituerade fenylpiperazinderivat
TW342389B (en)	1998-10-11	Arylalkyl-thiadiazinones
ES433148A1 (es)	1977-02-16	Procedimiento para preparar derivados de pirazol.
IE822330L (en)	1983-03-28	2,2-disubstituted-ethylamines
ES443738A1 (es)	1977-04-16	Procedimiento para la preparacion de nuevos derivados de xantina.
ES8506318A1 (es)	1985-07-01	Un procedimiento para preparar derivados de cefalosporina
ES8106511A1 (es)	1981-08-01	Procedimiento para la preparacion de acidos alcoxi benzofu- ran carboxilicos
ES8500953A1 (es)	1984-11-01	Procedimiento para preparar derivados de tieno-tiazol
ES389473A1 (es)	1974-12-16	Un procedimiento de preparacion de derivados de aminocarbo-nil-3 oxazolidinona-2.
SE7608306L (sv)	1977-06-17	Nya 5-fluoropyrimidin-4-on-derivat
ES445944A1 (es)	1977-05-16	Procedimiento de preparacion de derivados de 8-amino-teofi- lina.
ES437803A1 (es)	1977-01-01	Procedimiento para la preparacion de derivados de tiofeno.
ES475780A1 (es)	1980-01-16	Un proceso para la produccion de nueva penicilina y deriva- dos cefalosporinicos
ES442616A1 (es)	1977-12-01	Procedimiento de preparacion de acidos propionicos sustitui-dos por una radical cromonilo y sus esteres.
ES459705A1 (es)	1978-03-16	Procedimiento para la preparacion de derivados de hidracina-piridacina.
ES414340A1 (es)	1976-05-16	Procedimiento de preparacion de derivados de la n-(m-tri- fluormetiltio-fenil-)-piperazina.