ES435596A1 - Procedure for the obtaining of sulphonated derivatives of erythromycin in the c4 carbon hydroxide of the cladinosa ring. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of sulphonated derivatives of erythromycin in the c4 carbon hydroxide of the cladinosa ring. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES435596A1 ES435596A1 ES435596A ES435596A ES435596A1 ES 435596 A1 ES435596 A1 ES 435596A1 ES 435596 A ES435596 A ES 435596A ES 435596 A ES435596 A ES 435596A ES 435596 A1 ES435596 A1 ES 435596A1
- Authority
- ES
- Spain
- Prior art keywords
- radicals
- ring
- erythromycin
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- RXCVUXLCNLVYIA-UHFFFAOYSA-N orthocarbonic acid Chemical compound OC(O)(O)O RXCVUXLCNLVYIA-UHFFFAOYSA-N 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- AJSDVNKVGFVAQU-BIIVOSGPSA-N cladinose Chemical group O=CC[C@@](C)(OC)[C@@H](O)[C@H](C)O AJSDVNKVGFVAQU-BIIVOSGPSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000002516 radical scavenger Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
Abstract
Procedure for obtaining sulfonated derivatives of erythromycin in the hydroxyl of carbon C4'' of the cladinose ring, characterized in that a compound of general formula II, **(See formula)** where: R1 can be H, aliphatic acyl radicals of 1 to 4 carbon atoms or benzoyl radicals, optionally substituted by alkyloxy radicals, it is reacted at room temperature with a chloride or anhydride of an alkyl or arylsulfonic acid in an anhydrous solvent and, at the same time, it is a scavenger of the hydrochloric acid that is evolved during the reaction, to obtain a compound of general formula I, **(See formula)** where: R can be a C1-4 -alkyl radical or a benzene ring, optionally substituted by alkyl, halogen, nitro, alkyloxy or acetamido radicals, R1 can be H, aliphatic acyl radicals of 1 to 4 carbon atoms or benzoyl radicals, optionally substituted by alkyloxy radicals, and X is an oxygen atom. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES435596A ES435596A1 (en) | 1975-03-13 | 1975-03-13 | Procedure for the obtaining of sulphonated derivatives of erythromycin in the c4 carbon hydroxide of the cladinosa ring. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES435596A ES435596A1 (en) | 1975-03-13 | 1975-03-13 | Procedure for the obtaining of sulphonated derivatives of erythromycin in the c4 carbon hydroxide of the cladinosa ring. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES435596A1 true ES435596A1 (en) | 1977-11-01 |
Family
ID=8468851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435596A Expired ES435596A1 (en) | 1975-03-13 | 1975-03-13 | Procedure for the obtaining of sulphonated derivatives of erythromycin in the c4 carbon hydroxide of the cladinosa ring. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES435596A1 (en) |
-
1975
- 1975-03-13 ES ES435596A patent/ES435596A1/en not_active Expired
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