ES435624A1 - Aminotetralol compounds - Google Patents
Aminotetralol compoundsInfo
- Publication number
- ES435624A1 ES435624A1 ES435624A ES435624A ES435624A1 ES 435624 A1 ES435624 A1 ES 435624A1 ES 435624 A ES435624 A ES 435624A ES 435624 A ES435624 A ES 435624A ES 435624 A1 ES435624 A1 ES 435624A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- denotes
- groups
- nhr
- aminotetralol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds of the formula: < IMAGE > in which Z<1> and Z<2> denote hydrogen or alkyl and R denotes one of the groups -NHR<1>, -NHCH2R<2> and -NHCHR<3>R<4>, in which R<1>, R<2>, R <3 and R<4> have the meanings given in Claim 1, exert a potent bronchodilator action the compounds and their salts are suitable for the therapy and prophylaxis of asthma and angina pectoris. They are prepared by reduction of corresponding 1,2,3,4-tetrahydro-2-(Q)-naphthalene-1-ones, in which Q denotes one of the groups -NHR<1>, -NHCOR<2> and -N=CR<3>R<4> if Q denotes one of the two last-mentioned groups, it is additionally reduced.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4463174A JPS50148341A (en) | 1974-04-19 | 1974-04-19 | |
| JP4609774A JPS50140432A (en) | 1974-04-23 | 1974-04-23 | |
| JP49047211A JPS5826332B2 (en) | 1974-04-25 | 1974-04-25 | Tetralolka Gobutsu no Seizouhou |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES435624A1 true ES435624A1 (en) | 1977-03-16 |
Family
ID=27291968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435624A Expired ES435624A1 (en) | 1974-04-19 | 1975-03-14 | Aminotetralol compounds |
Country Status (10)
| Country | Link |
|---|---|
| CH (1) | CH617180A5 (en) |
| DE (1) | DE2514455A1 (en) |
| DK (1) | DK87275A (en) |
| ES (1) | ES435624A1 (en) |
| FI (1) | FI751146A7 (en) |
| FR (1) | FR2267763B1 (en) |
| GB (1) | GB1502155A (en) |
| NL (1) | NL7504551A (en) |
| NO (1) | NO750835L (en) |
| SE (1) | SE7504450L (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5314916A (en) * | 1993-04-19 | 1994-05-24 | Alcon Laboratories, Inc. | B2 adrenegic agonists and use thereof in the treatment of glaucoma |
-
1975
- 1975-03-04 DK DK87275*#A patent/DK87275A/en unknown
- 1975-03-12 NO NO750835A patent/NO750835L/no unknown
- 1975-03-14 ES ES435624A patent/ES435624A1/en not_active Expired
- 1975-03-24 FR FR7509116A patent/FR2267763B1/fr not_active Expired
- 1975-04-03 DE DE19752514455 patent/DE2514455A1/en not_active Withdrawn
- 1975-04-04 CH CH432175A patent/CH617180A5/en not_active IP Right Cessation
- 1975-04-16 NL NL7504551A patent/NL7504551A/en not_active Application Discontinuation
- 1975-04-17 SE SE7504450A patent/SE7504450L/en unknown
- 1975-04-17 FI FI751146A patent/FI751146A7/fi not_active Application Discontinuation
- 1975-04-21 GB GB16345/75A patent/GB1502155A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB1502155A (en) | 1978-02-22 |
| FI751146A7 (en) | 1975-10-20 |
| SE7504450L (en) | 1975-10-20 |
| FR2267763A1 (en) | 1975-11-14 |
| NO750835L (en) | 1975-10-21 |
| DK87275A (en) | 1975-10-20 |
| CH617180A5 (en) | 1980-05-14 |
| NL7504551A (en) | 1975-10-21 |
| FR2267763B1 (en) | 1978-06-30 |
| AU7904575A (en) | 1976-09-16 |
| DE2514455A1 (en) | 1975-10-30 |
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