ES437331A1 - Procedure for the polymerization substantially anhydra, catalyzed with bases of lactamas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the polymerization substantially anhydra, catalyzed with bases of lactamas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES437331A1
ES437331A1 ES437331A ES43733176A ES437331A1 ES 437331 A1 ES437331 A1 ES 437331A1 ES 437331 A ES437331 A ES 437331A ES 43733176 A ES43733176 A ES 43733176A ES 437331 A1 ES437331 A1 ES 437331A1
Authority
ES
Spain
Prior art keywords
group
see formula
hydrogen atom
atom
radicals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES437331A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5066374A external-priority patent/JPS539238B2/ja
Priority claimed from JP5225474A external-priority patent/JPS539239B2/ja
Priority claimed from JP6078774A external-priority patent/JPS539240B2/ja
Priority claimed from JP9199674A external-priority patent/JPS5123284A/en
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of ES437331A1 publication Critical patent/ES437331A1/en
Expired legal-status Critical Current

Links

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A procedure for the production of new penicillin and cephalosporin derivatives represented by the general formula (I): **(See formula)** where R represents an amino acid residue; R1 represents a hydrogen atom, a blocking group or a salt-forming cation; n represents 1 or 2; the n radicals X represent an oxygen atom and are linked in any combination at positions 2, 3 and 5 of the piperazine ring; m represents 4-n; each pair of radicals R2 and R3 are linked to the same carbon atom and m pairs of radicals R2 and R3, which may be the same or different, individually represent a hydrogen atom or an alkyl, cycloalkyl, aryl, acyl, aralkyl, alkoxycarbonylalkyl group, acyloxyalkyl, alkoxy, alkoxycarbonyl, cycloalkyloxycarbonyl, aralkoxycarbonyl, or substituted or unsubstituted aryloxycarbonyl; any pair of R2 and R3 together with a common carbon atom can form a cycloalkyl ring; A represents a hydrogen atom, or an alkyl, alkenyl, alkynyl, alkadienyl, cycloalkyl, cycloalkenyl, cycloalkadienyl, aryl, aralkyl acyl, acyloxy, alkoxy, cycloalkyloxy, aryloxy alkoxycarbonyl, cycloalkyloxycarbonyl, aryloxycarbonyl, aralkoxycarbonyl, alkylsulfonyl, cicloalguilsulfonilo, arylsulfonyl, carbamoyl, thiocarbamoyl, acylcarbamoyl, alkylsulfonylcarbamoyl, arylsulfonylcarbamoyl, alkoxycarbonylthioalkyl, alkoxythiocarbonylthioalkyl, substituted or unsubstituted; Y represents an oxygen or sulfur atom; and (see formula) represents (see formula) where R4 represents a hydrogen atom, a halogen atom, a hydroxy group, a cyano group, an azido group, or an organic group linked through 0 or S; whose procedure consists of reacting a compound represented by the general formula (II): **(See formula)** where R7 represents a hydrogen atom, a silicon-containing group or a phosphorous-containing group; (see formula) are those defined above, with a reactive derivative in the (thio) carboxyl group of a compound represented by the general formula (III): **(See formula)** (Machine-translation by Google Translate, not legally binding)
ES437331A 1974-05-09 1976-12-14 Procedure for the polymerization substantially anhydra, catalyzed with bases of lactamas. (Machine-translation by Google Translate, not legally binding) Expired ES437331A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5066374A JPS539238B2 (en) 1974-05-09 1974-05-09
JP5225474A JPS539239B2 (en) 1974-05-13 1974-05-13
JP6078774A JPS539240B2 (en) 1974-05-31 1974-05-31
JP9199674A JPS5123284A (en) 1974-08-13 1974-08-13 Shinkina penishirinruino seizoho

Publications (1)

Publication Number Publication Date
ES437331A1 true ES437331A1 (en) 1977-05-16

Family

ID=27462534

Family Applications (2)

Application Number Title Priority Date Filing Date
ES437331A Expired ES437331A1 (en) 1974-05-09 1976-12-14 Procedure for the polymerization substantially anhydra, catalyzed with bases of lactamas. (Machine-translation by Google Translate, not legally binding)
ES454264A Expired ES454264A1 (en) 1974-05-09 1976-12-15 A PROCEDURE FOR THE PRODUCTION OF NEW DERIVATIVES OF PENICILLIN AND CEPHALOSPORIN.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES454264A Expired ES454264A1 (en) 1974-05-09 1976-12-15 A PROCEDURE FOR THE PRODUCTION OF NEW DERIVATIVES OF PENICILLIN AND CEPHALOSPORIN.

Country Status (1)

Country Link
ES (2) ES437331A1 (en)

Also Published As

Publication number Publication date
ES454264A1 (en) 1977-12-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970210