ES439074A1 - PROCEDURE FOR OBTAINING PHARMACEUTICAL COMPOSITIONS WITH IMPROVED ENTERAL RESORPTION PROPERTIES. - Google Patents

PROCEDURE FOR OBTAINING PHARMACEUTICAL COMPOSITIONS WITH IMPROVED ENTERAL RESORPTION PROPERTIES.

Info

Publication number
ES439074A1
ES439074A1 ES439074A ES439074A ES439074A1 ES 439074 A1 ES439074 A1 ES 439074A1 ES 439074 A ES439074 A ES 439074A ES 439074 A ES439074 A ES 439074A ES 439074 A1 ES439074 A1 ES 439074A1
Authority
ES
Spain
Prior art keywords
component
procedure
liquid
pharmaceutical compositions
aggregate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES439074A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES439074A1 publication Critical patent/ES439074A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for obtaining pharmaceutical compositions with improved whole resorption properties, which, in the form of aggregates with a diameter of maximum 20,000 Å, comprise a component a) containing at least one pharmaceutically acceptable active agent, such as a derivative of lysergic acid or a derivative of dopamine, and a component b) containing at least one pharmaceutically acceptable emulsifier, such as a non-tenside ionogenic or an alkali metal dialkyl sulfosuccinate; component b) having an average NHL value of 10 to 30 and associating in an amount of more than 10 times greater by weight than that of component a), conveniently formulating at least one additional pharmaceutical support in the aggregate and/or portion that it is not part of the aggregate; characterized in that it comprises dissolving said active agents, with slight heating, in said tensides, optionally in the presence of liquid support materials; and then dilute with more liquid support materials while homogenizing the combination with ultrasonic waves or high-speed stirrers, to cause a physico-chemical reaction among the participants in the process and thereby form the liquid pharmaceutical composition, after which, and optionally, the liquid support material is separated to form a solid pharmaceutical composition. (Machine-translation by Google Translate, not legally binding)
ES439074A 1974-07-04 1975-07-02 PROCEDURE FOR OBTAINING PHARMACEUTICAL COMPOSITIONS WITH IMPROVED ENTERAL RESORPTION PROPERTIES. Expired ES439074A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH920474 1974-07-04

Publications (1)

Publication Number Publication Date
ES439074A1 true ES439074A1 (en) 1977-05-16

Family

ID=4349465

Family Applications (1)

Application Number Title Priority Date Filing Date
ES439074A Expired ES439074A1 (en) 1974-07-04 1975-07-02 PROCEDURE FOR OBTAINING PHARMACEUTICAL COMPOSITIONS WITH IMPROVED ENTERAL RESORPTION PROPERTIES.

Country Status (18)

Country Link
JP (1) JPS5132722A (en)
AT (1) AT359196B (en)
AU (1) AU507674B2 (en)
BE (1) BE831041A (en)
CA (1) CA1057196A (en)
DE (1) DE2528257C2 (en)
ES (1) ES439074A1 (en)
FR (1) FR2276833A1 (en)
GB (1) GB1513383A (en)
HK (1) HK17281A (en)
HU (1) HU172531B (en)
IE (1) IE41573B1 (en)
IL (1) IL47623A (en)
MY (1) MY8100372A (en)
NL (1) NL7507745A (en)
PH (1) PH13763A (en)
SE (1) SE436831B (en)
ZA (1) ZA754303B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1090703B (en) * 1976-12-03 1985-06-26 Scherer Ltd R P IMPROVEMENT IN USEFUL COMPOSITIONS SUCH AS DRUG VEHICLES
DE2707878C2 (en) * 1977-02-24 1986-01-30 Kali-Chemie Pharma Gmbh, 3000 Hannover Use of mono- and / or diglycerides of medium-chain fatty acids
SE442265B (en) * 1978-12-21 1985-12-16 Sandoz Ag FIXED, ENTERAL TRANSFER COMPOSITION IN UNIT FORM ORAL SUPPLY INCLUDING AN ERGOTAL KALOID
JPS56104813A (en) * 1980-01-25 1981-08-20 Takeda Chem Ind Ltd Composition for rectal infusion containing compound having beta-lactam ring
AU543727B2 (en) 1980-06-02 1985-05-02 Ayerst Mckenna & Harrison Inc. Injectable composition of rapamycin
US4366145A (en) * 1981-06-24 1982-12-28 Sandoz, Inc. Soft gelatin capsule with a liquid ergot alkaloid center fill solution and method of preparation
DE3829643A1 (en) * 1988-09-01 1990-03-15 Roecar Holdings Nv PHYTO AND ZOOSTEROLS AND THEIR DERIVATIVES WITH IMPROVED WATER SOLUBILITY

Also Published As

Publication number Publication date
MY8100372A (en) 1981-12-31
IE41573B1 (en) 1980-01-30
ZA754303B (en) 1977-02-23
CA1057196A (en) 1979-06-26
HU172531B (en) 1978-09-28
FR2276833A1 (en) 1976-01-30
FR2276833B1 (en) 1978-11-10
IL47623A (en) 1979-05-31
NL7507745A (en) 1976-01-06
IL47623A0 (en) 1975-10-15
ATA510975A (en) 1980-03-15
SE436831B (en) 1985-01-28
BE831041A (en) 1976-01-05
JPS5132722A (en) 1976-03-19
AU507674B2 (en) 1980-02-21
GB1513383A (en) 1978-06-07
AT359196B (en) 1980-10-27
AU8273675A (en) 1977-01-06
PH13763A (en) 1980-09-18
DE2528257C2 (en) 1986-02-13
SE7507413L (en) 1976-01-05
DE2528257A1 (en) 1976-01-22
IE41573L (en) 1976-01-04
HK17281A (en) 1981-05-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19910205