ES439948A1 - Steroids of the d-homopregnane series - Google Patents

Steroids of the d-homopregnane series

Info

Publication number
ES439948A1
ES439948A1 ES439948A ES439948A ES439948A1 ES 439948 A1 ES439948 A1 ES 439948A1 ES 439948 A ES439948 A ES 439948A ES 439948 A ES439948 A ES 439948A ES 439948 A1 ES439948 A1 ES 439948A1
Authority
ES
Spain
Prior art keywords
hydrogen
series
fluorine
homopregnane
steroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES439948A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES439948A1 publication Critical patent/ES439948A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B19/00—Oxazine dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A procedure for the preparation of D-homosteroids of the pregnane series of the general formula ** (See formula) ** in which R6 represents a hydrogen, fluorine or chlorine atom or the methyl group, R9 represents a fluorine, chlorine or bromine atom and R17 and R21 each independently represent a hydroxy or acyloxy group, and their 1,2-dehydro derivatives, characterized in that it comprises treating with hydrogen fluoride, hydrogen chloride or hydrogen bromide a D-homo-steroid of the general formula ** (See formula) ** and its 1,2-dehydro derivatives. (Machine-translation by Google Translate, not legally binding)
ES439948A 1972-03-29 1975-08-01 Steroids of the d-homopregnane series Expired ES439948A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH466672A CH571018A5 (en) 1972-03-29 1972-03-29

Publications (1)

Publication Number Publication Date
ES439948A1 true ES439948A1 (en) 1977-07-01

Family

ID=4280344

Family Applications (13)

Application Number Title Priority Date Filing Date
ES413083A Expired ES413083A1 (en) 1972-03-29 1973-03-28 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS FROM THE PREGNANE SERIES.
ES439958A Expired ES439958A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439948A Expired ES439948A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439952A Expired ES439952A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439957A Expired ES439957A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439949A Expired ES439949A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439951A Expired ES439951A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439956A Expired ES439956A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439959A Expired ES439959A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439954A Expired ES439954A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNATE SERIES.
ES439955A Expired ES439955A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439953A Expired ES439953A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS, FROM THE PREGNANE SERIES.
ES439950A Expired ES439950A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES413083A Expired ES413083A1 (en) 1972-03-29 1973-03-28 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS FROM THE PREGNANE SERIES.
ES439958A Expired ES439958A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.

Family Applications After (10)

Application Number Title Priority Date Filing Date
ES439952A Expired ES439952A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439957A Expired ES439957A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439949A Expired ES439949A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439951A Expired ES439951A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439956A Expired ES439956A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439959A Expired ES439959A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNANO SERIES.
ES439954A Expired ES439954A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS OF THE PREGNATE SERIES.
ES439955A Expired ES439955A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series
ES439953A Expired ES439953A1 (en) 1972-03-29 1975-08-01 A PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS, FROM THE PREGNANE SERIES.
ES439950A Expired ES439950A1 (en) 1972-03-29 1975-08-01 Steroids of the d-homopregnane series

Country Status (27)

Country Link
JP (2) JPS5844360B2 (en)
KR (3) KR780000672B1 (en)
AR (1) AR208389A1 (en)
AT (1) AT326282B (en)
AU (1) AU468918B2 (en)
BE (1) BE797412A (en)
CA (1) CA1006156A (en)
CH (1) CH571018A5 (en)
DD (1) DD105216A5 (en)
DE (1) DE2314592C2 (en)
DK (1) DK135722B (en)
ES (13) ES413083A1 (en)
FI (1) FI52099C (en)
FR (1) FR2182911B1 (en)
GB (1) GB1365469A (en)
HU (2) HU170428B (en)
IE (1) IE37444B1 (en)
IL (1) IL41752A (en)
LU (1) LU67304A1 (en)
NL (1) NL176945C (en)
NO (1) NO139524C (en)
PH (1) PH9660A (en)
PL (7) PL92130B1 (en)
SE (2) SE404530B (en)
SU (7) SU697054A3 (en)
YU (4) YU81573A (en)
ZA (1) ZA731563B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK142289B (en) * 1973-03-28 1980-10-06 Hoffmann La Roche Analogous procedure for the preparation of D-homopregn-4-ene-3,20-dione.
DE2442615A1 (en) * 1974-09-04 1976-03-18 Schering Ag NEW D-HOMO-STEROIDS
SE411351B (en) * 1974-10-07 1979-12-17 Hoffmann La Roche PROCEDURE FOR THE PREPARATION OF D-HOMOSTEROIDS FROM THE PREGNANCY SERIES
SE427276B (en) * 1975-04-03 1983-03-21 Hoffmann La Roche PROCEDURE FOR PREPARING D-HOMOSTEROIDS
AT356301B (en) * 1976-09-03 1980-04-25 Hoffmann La Roche METHOD FOR THE PRODUCTION OF NEW D-HOMOSTEROIDS
US4202841A (en) * 1977-08-25 1980-05-13 Hoffmann-La Roche Inc. D-Homopregnanes
DE3038855A1 (en) * 1980-10-10 1982-05-27 Schering Ag, 1000 Berlin Und 4619 Bergkamen NEW D-HOMO CORTICOIDS, THEIR PRODUCTION AND USE
DE3409554A1 (en) * 1984-03-13 1985-09-19 Schering AG, 1000 Berlin und 4709 Bergkamen NEW 6 (ALPHA) METHYL-D HOMO CORTICOIDS
JP5987451B2 (en) 2012-04-25 2016-09-07 富士ゼロックス株式会社 Post-processing apparatus and image forming apparatus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof

Also Published As

Publication number Publication date
SU509211A3 (en) 1976-03-30
IE37444L (en) 1973-09-29
HU170428B (en) 1977-06-28
YU56979A (en) 1980-09-25
AR208389A1 (en) 1976-12-27
YU35453B (en) 1981-02-28
ES439953A1 (en) 1977-06-16
YU56879A (en) 1980-09-25
ES439956A1 (en) 1977-06-01
AT326282B (en) 1975-12-10
NL176945C (en) 1985-07-01
KR780000672B1 (en) 1978-12-26
SE404530B (en) 1978-10-09
DK135722B (en) 1977-06-13
FI52099C (en) 1977-06-10
ES439954A1 (en) 1977-06-01
ES439950A1 (en) 1977-07-01
FI52099B (en) 1977-02-28
DK135722C (en) 1977-11-14
ES439957A1 (en) 1977-06-01
NL7304193A (en) 1973-10-02
JPS6052160B2 (en) 1985-11-18
DE2314592A1 (en) 1973-10-11
JPS5844360B2 (en) 1983-10-03
ES439959A1 (en) 1977-06-01
ZA731563B (en) 1973-11-28
KR780000675B1 (en) 1978-12-26
DD105216A5 (en) 1974-04-12
PL86797B1 (en) 1976-06-30
PL98710B1 (en) 1978-05-31
PL98712B1 (en) 1978-05-31
NO139524C (en) 1979-03-28
IL41752A0 (en) 1973-05-31
JPS495960A (en) 1974-01-19
DE2314592C2 (en) 1983-04-14
PL92076B1 (en) 1977-03-31
IE37444B1 (en) 1977-07-20
SE7602850L (en) 1976-02-27
ES439952A1 (en) 1977-07-01
PL98714B1 (en) 1978-05-31
JPS5877899A (en) 1983-05-11
SU492080A3 (en) 1975-11-15
FR2182911B1 (en) 1976-10-22
ATA270973A (en) 1975-02-15
NO139524B (en) 1978-12-18
YU81573A (en) 1980-12-31
SU506288A3 (en) 1976-03-05
NL176945B (en) 1985-02-01
SU612636A3 (en) 1978-06-25
KR780000673B1 (en) 1978-12-26
SU517263A3 (en) 1976-06-05
ES413083A1 (en) 1976-06-01
SU538665A3 (en) 1976-12-05
YU35775B (en) 1981-06-30
HU166580B (en) 1975-04-28
YU35452B (en) 1981-02-28
GB1365469A (en) 1974-09-04
AU468918B2 (en) 1976-01-29
ES439949A1 (en) 1977-07-01
PL92130B1 (en) 1977-03-31
CA1006156A (en) 1977-03-01
ES439951A1 (en) 1977-07-01
AU5320773A (en) 1974-09-12
ES439955A1 (en) 1977-06-01
BE797412A (en) 1973-09-28
LU67304A1 (en) 1974-10-09
PL92077B1 (en) 1977-03-31
SU697054A3 (en) 1979-11-05
FR2182911A1 (en) 1973-12-14
CH571018A5 (en) 1975-12-31
PH9660A (en) 1976-01-27
IL41752A (en) 1977-11-30
ES439958A1 (en) 1977-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19860215