ES440110A1 - Procedimiento para la obtencion de compuestos esteroides cardiotonicos. - Google Patents

Procedimiento para la obtencion de compuestos esteroides cardiotonicos.

Info

Publication number
ES440110A1
ES440110A1 ES440110A ES440110A ES440110A1 ES 440110 A1 ES440110 A1 ES 440110A1 ES 440110 A ES440110 A ES 440110A ES 440110 A ES440110 A ES 440110A ES 440110 A1 ES440110 A1 ES 440110A1
Authority
ES
Spain
Prior art keywords
formula
see formula
groups
hydrogen
esterified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES440110A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siphar SA
Original Assignee
Siphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siphar SA filed Critical Siphar SA
Publication of ES440110A1 publication Critical patent/ES440110A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES440110A 1974-08-08 1975-08-08 Procedimiento para la obtencion de compuestos esteroides cardiotonicos. Expired ES440110A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1085574A CH621803A5 (2) 1974-08-08 1974-08-08

Publications (1)

Publication Number Publication Date
ES440110A1 true ES440110A1 (es) 1977-02-16

Family

ID=4367535

Family Applications (1)

Application Number Title Priority Date Filing Date
ES440110A Expired ES440110A1 (es) 1974-08-08 1975-08-08 Procedimiento para la obtencion de compuestos esteroides cardiotonicos.

Country Status (12)

Country Link
US (1) US4000125A (2)
JP (1) JPS5141372A (2)
AR (1) AR217617A1 (2)
BE (1) BE832271A (2)
CA (1) CA1049499A (2)
CH (1) CH621803A5 (2)
DE (1) DE2534981A1 (2)
DK (1) DK139101B (2)
ES (1) ES440110A1 (2)
FR (1) FR2281124A1 (2)
GB (1) GB1484655A (2)
SE (1) SE418401B (2)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1144136B (it) * 1980-03-05 1986-10-29 Zenyaku Kogyo Kk Glucosidi di condurango agenti antitumorali che li comprendono e procedimento per la loro preparazione
US5373095A (en) * 1985-10-18 1994-12-13 The Upjohn Company Steroid compounds
IT1262931B (it) * 1992-01-16 1996-07-22 Zambon Spa Composti steroidei 17(piridazin-n-ossido)-sostituiti attivi sul sistema cardiovascolare
DE4227616C2 (de) * 1992-08-20 1995-04-13 Sigma Tau Ind Farmaceuti 17-(3-Furyl)-und 17-(4-Pyridazinyl)-5beta, 14beta-androstanderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammemsetzungen
US7875599B2 (en) * 2005-03-02 2011-01-25 University Of Maryland C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens, in vitro biological activities, pharmacokinetics and antitumor activity
GB2470873A (en) * 2008-03-12 2010-12-08 Univ Maryland Androgen receptor inactivation contributes to antitumor efficacy of CYP17 inhibitors in prostrate cancer
US20100048524A1 (en) * 2008-03-14 2010-02-25 Angela Brodie Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
GB2470700B (en) 2008-03-25 2012-08-08 Univ Maryland C-17 heteroaryl steroidal CYP17 inhibitors
US8785423B2 (en) * 2008-04-14 2014-07-22 University Of Maryland, Baltimore Compositions and methods of inducing endoplasmic reticulum stress response for the treatment of cell proliferative diseases
WO2010091303A1 (en) 2009-02-05 2010-08-12 Tokai Pharmaceuticals Novel steroidal cyp17 inhibitors/antiandrogens
WO2010091306A1 (en) 2009-02-05 2010-08-12 Tokai Pharmaceuticals Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
WO2011017534A2 (en) 2009-08-07 2011-02-10 Tokai Pharmaceuticals, Inc. Treatment of prostate cancer
KR20150127720A (ko) 2013-03-14 2015-11-17 유니버시티 오브 매릴랜드, 발티모어 안드로겐 수용체 하향 조절제 및 그의 용도
CA2920317A1 (en) 2013-08-12 2015-02-19 Tokai Pharmaceuticals, Inc. Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
WO2017001204A1 (en) * 2015-06-29 2017-01-05 Universiteit Gent Methods for the site-selective coupling of a first agent to a second agent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3838163A (en) * 1968-11-22 1974-09-24 Hoffmann La Roche Substituted isoxazole derivatives as steroid intermediates

Also Published As

Publication number Publication date
DK139101C (2) 1979-05-21
CH621803A5 (2) 1981-02-27
SE7508908L (sv) 1976-02-09
DE2534981A1 (de) 1976-02-19
DK358875A (2) 1976-02-09
FR2281124B1 (2) 1980-05-16
JPS5141372A (2) 1976-04-07
CA1049499A (en) 1979-02-27
BE832271A (fr) 1975-12-01
DK139101B (da) 1978-12-18
AR217617A1 (es) 1980-04-15
US4000125A (en) 1976-12-28
FR2281124A1 (fr) 1976-03-05
SE418401B (sv) 1981-05-25
GB1484655A (en) 1977-09-01

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