ES443835A2 - Un procedimiento para la preparacion de la forma de alto punto de fusion del acido quenodesoxicolico. - Google Patents

Un procedimiento para la preparacion de la forma de alto punto de fusion del acido quenodesoxicolico.

Info

Publication number: ES443835A2
Authority: ES; Spain
Prior art keywords: acid; translation; preparation; machine; legally binding
Prior art date: 1973-01-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES443835A

Other languages

English (en)

Inventor

H F Frost

F Fabian

C J Sharpe

W A Jones

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Union International Co Ltd

Original Assignee

Union International Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-01-19

Filing date

1975-12-23

Publication date

1977-10-01

1973-01-19 Priority claimed from ES410785A external-priority patent/ES410785A1/es

1975-12-23 Application filed by Union International Co Ltd filed Critical Union International Co Ltd

1977-10-01 Publication of ES443835A2 publication Critical patent/ES443835A2/es

Status Expired legal-status Critical Current

Links

239000002253 acid Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title abstract 2
230000004927 fusion Effects 0.000 title 1
238000002844 melting Methods 0.000 abstract 4
230000008018 melting Effects 0.000 abstract 4
RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 abstract 3
229960001091 chenodeoxycholic acid Drugs 0.000 abstract 3
239000007900 aqueous suspension Substances 0.000 abstract 2
RUDATBOHQWOJDD-BSWAIDMHSA-N chenodeoxycholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-BSWAIDMHSA-N 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 1
150000001801 chenodeoxycholic acids Chemical class 0.000 abstract 1
238000010899 nucleation Methods 0.000 abstract 1
239000011973 solid acid Substances 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)

ES443835A 1973-01-19 1975-12-23 Un procedimiento para la preparacion de la forma de alto punto de fusion del acido quenodesoxicolico. Expired ES443835A2 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ES410785A ES410785A1 (es)	1972-01-20	1973-01-19	Un procedimiento para la purificacion de acido quenodesoxicolico crudo.
GB55575/74A GB1532413A (en)	1974-12-23	1974-12-23	Chenodeoxycholic acid

Publications (1)

Publication Number	Publication Date
ES443835A2 true ES443835A2 (es)	1977-10-01

Family

ID=10474304

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES443835A Expired ES443835A2 (es)	1973-01-19	1975-12-23	Un procedimiento para la preparacion de la forma de alto punto de fusion del acido quenodesoxicolico.

Country Status (7)

Country	Link
US (1)	US4022806A (es)
JP (1)	JPS51110553A (es)
AU (1)	AU8772375A (es)
DE (1)	DE2557287A1 (es)
ES (1)	ES443835A2 (es)
GB (1)	GB1532413A (es)
SE (1)	SE7514548L (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2613346C3 (de) *	1976-03-29	1981-07-23	Diamalt AG, 8000 München	Monoklin kristalline Chenodesoxycholsäure und Verfahren zu ihrer Herstellung
US4186143A (en) *	1977-06-20	1980-01-29	Canada Packers Limited	Chenodeoxycholic acid recovery process
US4213911A (en) *	1978-11-07	1980-07-22	Canada Packers Limited	Process for preparing high-melting chenodeoxycholic acid
FR2446293A1 (fr) *	1978-12-11	1980-08-08	Roussel Uclaf	Procede de purification de l'acide chenodesoxycholique
IT1165251B (it) *	1979-07-12	1987-04-22	Blasinachim Spa	Metodo di furificazione dell'acido chenodesossicolico
IT1165253B (it) *	1979-07-12	1987-04-22	Blasinachim Spa	Procedimento di fabbricazione di acido chenodesossicolico cristallino puro
IT1136624B (it) *	1981-05-21	1986-09-03	Erregierre Ind Chim Spa	Prodotti di salificazione di acidi colici,processo per la loro preparazione e composizioni terapeutiche che li comprendono come principio attivo
UA25898A1 (uk) *	1987-02-02	1999-02-26	Пфайзер Інк.	Спосіб одержаhhя кристалічhої hатрієвої солі 5-хлор-3-(2-теhоїл)-2-оксііhдол-1-карбоксаміду
IL150907A (en) *	2002-07-25	2007-07-04	Stephan Cherkez	Process for the preparation of stable amorphous calcium pseudomonate
US20060074057A1 (en) *	2004-10-04	2006-04-06	Eric Marchewitz	Use of chenodeoxycholic acid for reducing adipose tissue
ITMI20061735A1 (it) *	2006-09-12	2008-03-13	Dipharma Spa	Procedimento per la preparazione di acidi colanici
LT3077047T (lt) *	2013-12-04	2019-08-26	Galmed Research & Development Ltd.	Aramcholio druskos
WO2016199137A1 (en)	2015-06-10	2016-12-15	Galmed Research And Development Ltd.	Low dose compositions of aramchol salts
US11571431B2 (en)	2013-12-04	2023-02-07	Galmed Research And Development Ltd	Aramchol salts
CN113666982A (zh) *	2021-08-23	2021-11-19	江西邦泰绿色生物合成生态产业园发展有限公司	一种基于生物酶法合成熊去氧胆酸的纯化方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3839565A (en) *	1972-10-31	1974-10-01	Intellectual Property Dev Corp	Chemical process
US3833620A (en) *	1972-11-16	1974-09-03	Intellectual Property Dev Corp	Production of chenodeoxycholic acid

1974
- 1974-12-23 GB GB55575/74A patent/GB1532413A/en not_active Expired
1975
- 1975-12-19 DE DE19752557287 patent/DE2557287A1/de active Pending
- 1975-12-19 AU AU87723/75A patent/AU8772375A/en not_active Expired
- 1975-12-22 SE SE7514548A patent/SE7514548L/xx unknown
- 1975-12-23 JP JP50153922A patent/JPS51110553A/ja active Pending
- 1975-12-23 US US05/643,902 patent/US4022806A/en not_active Expired - Lifetime
- 1975-12-23 ES ES443835A patent/ES443835A2/es not_active Expired

Also Published As

Publication number	Publication date
AU8772375A (en)	1977-06-23
SE7514548L (sv)	1976-06-24
GB1532413A (en)	1978-11-15
JPS51110553A (es)	1976-09-30
US4022806A (en)	1977-05-10
DE2557287A1 (de)	1976-07-01

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Legal Events

Date	Code	Title	Description
2017-07-05	FD2A	Announcement of lapse in spain	Effective date: 20170705