ES449095A1 - Procedimiento para la preparacion de pirrolidonas. - Google Patents
Procedimiento para la preparacion de pirrolidonas.Info
- Publication number
- ES449095A1 ES449095A1 ES449095A ES449095A ES449095A1 ES 449095 A1 ES449095 A1 ES 449095A1 ES 449095 A ES449095 A ES 449095A ES 449095 A ES449095 A ES 449095A ES 449095 A1 ES449095 A1 ES 449095A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- properties
- pyrrolidones
- hand
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004040 pyrrolidinones Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000003033 spasmogenic effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752528664 DE2528664A1 (de) | 1975-06-27 | 1975-06-27 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449095A1 true ES449095A1 (es) | 1977-12-16 |
Family
ID=5950059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449095A Expired ES449095A1 (es) | 1975-06-27 | 1976-06-22 | Procedimiento para la preparacion de pirrolidonas. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS525764A (de) |
| AT (1) | AT365575B (de) |
| BE (1) | BE843505A (de) |
| CH (1) | CH623809A5 (de) |
| DE (1) | DE2528664A1 (de) |
| DK (1) | DK287476A (de) |
| ES (1) | ES449095A1 (de) |
| FR (1) | FR2316943A1 (de) |
| GB (1) | GB1553595A (de) |
| IL (1) | IL49916A0 (de) |
| LU (1) | LU75235A1 (de) |
| NL (1) | NL7606773A (de) |
| SE (1) | SE7607331L (de) |
| ZA (1) | ZA763802B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1077948A (en) * | 1976-08-06 | 1980-05-20 | Albin J. Nelson | 1,-5 disubstituted-2-pyrrolidones and processes for their production |
| US4772601A (en) * | 1988-01-25 | 1988-09-20 | Hoechst-Roussel Pharmaceuticals, Inc. | 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use |
| AP2001002357A0 (en) * | 1999-12-22 | 2001-12-31 | Pfizer Prod Inc | EP4 receptor selective agonists in the treatment of osteoporosis. |
| WO2002024647A1 (en) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
| PT1339678E (pt) | 2000-11-27 | 2007-11-30 | Pfizer Prod Inc | Agonistas selectivos do receptor ep4 no tratamento de osteoporose |
| RU2296122C2 (ru) | 2001-07-16 | 2007-03-27 | Ф.Хоффманн-Ля Рош Аг | Производные 2-пирролидона в качестве простаноидных агонистов и фармацевтическая композиция |
| ES2254726T3 (es) | 2001-07-16 | 2006-06-16 | F. Hoffmann-La Roche Ag | Analogos de prostaglandina como agonistas receptores de ep4. |
| NZ530885A (en) | 2001-07-23 | 2007-09-28 | Ono Pharmaceutical Co | Remedies for diseases with bone mass loss having EP4 agonist as the active ingredient |
| CA2478653A1 (en) * | 2002-03-18 | 2003-09-25 | Pfizer Products Inc. | Methods of treatment with selective ep4 receptor agonists |
| US6573294B1 (en) | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| RU2311409C2 (ru) | 2003-01-10 | 2007-11-27 | Ф.Хоффманн-Ля Рош Аг | Производные 2-пиперидона в качестве агонистов простагландина |
| US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| CN107802623B (zh) | 2012-07-19 | 2020-10-30 | 开曼化学股份有限公司 | 用于ep4介导的骨相关疾病和病症的二氟内酰胺组合物 |
| JP6368351B2 (ja) | 2013-03-15 | 2018-08-01 | ケイマン ケミカル カンパニー， インコーポレーテッド | ジフルオロラクタムアナログを合成する方法 |
| EP3235817B1 (de) | 2013-03-15 | 2018-12-12 | Cayman Chemical Company, Incorporated | Lactamverbindungen als ep4-rezeptorselektive agonisten zur verwendung bei der behandlung von ep4-vermittelten erkrankungen und zuständen |
| WO2014144610A1 (en) * | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
| JP2016527006A (ja) | 2013-07-19 | 2016-09-08 | ケイマン ケミカル カンパニー， インコーポレーテッド | 骨成長を促進するための方法、システム、及び組成物 |
-
1975
- 1975-06-27 DE DE19752528664 patent/DE2528664A1/de not_active Withdrawn
-
1976
- 1976-06-22 ES ES449095A patent/ES449095A1/es not_active Expired
- 1976-06-22 NL NL7606773A patent/NL7606773A/xx not_active Application Discontinuation
- 1976-06-24 LU LU75235A patent/LU75235A1/xx unknown
- 1976-06-24 CH CH809976A patent/CH623809A5/de not_active IP Right Cessation
- 1976-06-24 SE SE7607331A patent/SE7607331L/xx unknown
- 1976-06-25 DK DK287476A patent/DK287476A/da unknown
- 1976-06-25 AT AT0467976A patent/AT365575B/de active
- 1976-06-25 GB GB26564/76A patent/GB1553595A/en not_active Expired
- 1976-06-25 IL IL49916A patent/IL49916A0/xx unknown
- 1976-06-25 ZA ZA763802A patent/ZA763802B/xx unknown
- 1976-06-26 JP JP51075954A patent/JPS525764A/ja active Pending
- 1976-06-28 BE BE168390A patent/BE843505A/xx not_active IP Right Cessation
- 1976-06-28 FR FR7619563A patent/FR2316943A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ZA763802B (en) | 1977-05-25 |
| DK287476A (da) | 1976-12-28 |
| LU75235A1 (de) | 1977-03-16 |
| FR2316943A1 (fr) | 1977-02-04 |
| DE2528664A1 (de) | 1977-01-13 |
| IL49916A0 (en) | 1976-08-31 |
| GB1553595A (en) | 1979-09-26 |
| FR2316943B1 (de) | 1978-11-03 |
| ATA467976A (de) | 1981-06-15 |
| SE7607331L (sv) | 1976-12-28 |
| NL7606773A (nl) | 1976-12-29 |
| AT365575B (de) | 1982-01-25 |
| CH623809A5 (en) | 1981-06-30 |
| JPS525764A (en) | 1977-01-17 |
| BE843505A (fr) | 1976-12-28 |
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