ES449095A1 - Procedimiento para la preparacion de pirrolidonas. - Google Patents
Procedimiento para la preparacion de pirrolidonas.Info
- Publication number
- ES449095A1 ES449095A1 ES449095A ES449095A ES449095A1 ES 449095 A1 ES449095 A1 ES 449095A1 ES 449095 A ES449095 A ES 449095A ES 449095 A ES449095 A ES 449095A ES 449095 A1 ES449095 A1 ES 449095A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- properties
- pyrrolidones
- hand
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004040 pyrrolidinones Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000003033 spasmogenic effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752528664 DE2528664A1 (de) | 1975-06-27 | 1975-06-27 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449095A1 true ES449095A1 (es) | 1977-12-16 |
Family
ID=5950059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449095A Expired ES449095A1 (es) | 1975-06-27 | 1976-06-22 | Procedimiento para la preparacion de pirrolidonas. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS525764A (de) |
| AT (1) | AT365575B (de) |
| BE (1) | BE843505A (de) |
| CH (1) | CH623809A5 (de) |
| DE (1) | DE2528664A1 (de) |
| DK (1) | DK287476A (de) |
| ES (1) | ES449095A1 (de) |
| FR (1) | FR2316943A1 (de) |
| GB (1) | GB1553595A (de) |
| IL (1) | IL49916A0 (de) |
| LU (1) | LU75235A1 (de) |
| NL (1) | NL7606773A (de) |
| SE (1) | SE7607331L (de) |
| ZA (1) | ZA763802B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE423813B (sv) * | 1976-08-06 | 1982-06-07 | Pfizer | Forfarande for framstellning av 1,5-disubstituerade pyrrolidoner med terapeutiska egenskaper |
| US4772601A (en) * | 1988-01-25 | 1988-09-20 | Hoechst-Roussel Pharmaceuticals, Inc. | 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use |
| EA005293B1 (ru) * | 1999-12-22 | 2004-12-30 | Пфайзер Продактс Инк. | Производные пирролидин-2-она и их применение при лечении остеопороза |
| WO2002024647A1 (en) * | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
| EA200300379A1 (ru) | 2000-11-27 | 2003-08-28 | Пфайзер Продактс Инк. | Селективные агонисты рецептора ep4 в лечении остеопороза |
| RU2288913C2 (ru) | 2001-07-16 | 2006-12-10 | Ф.Хоффманн-Ля Рош Аг | Аналоги простагландинов, способ их получения и фармацевтическая композиция, обладающая селективной агонистической активностью в отношении рецептора ep4 |
| RU2296122C2 (ru) | 2001-07-16 | 2007-03-27 | Ф.Хоффманн-Ля Рош Аг | Производные 2-пирролидона в качестве простаноидных агонистов и фармацевтическая композиция |
| IL159996A0 (en) | 2001-07-23 | 2004-06-20 | Ono Pharmaceutical Co | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
| AU2003207900A1 (en) * | 2002-03-18 | 2003-09-29 | Pfizer Products Inc. | Methods of treatment with selective ep4 receptor agonists |
| US6573294B1 (en) | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| CN1735597A (zh) | 2003-01-10 | 2006-02-15 | 霍夫曼-拉罗奇有限公司 | 作为前列腺素激动剂的2－哌啶酮衍生物 |
| US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| US9440919B2 (en) | 2012-07-19 | 2016-09-13 | Cayman Chemical Company, Inc. | Difluorolactam compositions for EP4-mediated osteo related diseases and conditions |
| ES2635635T3 (es) | 2013-03-15 | 2017-10-04 | Cayman Chemical Company, Incorporated | Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4 |
| WO2014144610A1 (en) * | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
| JP6368351B2 (ja) | 2013-03-15 | 2018-08-01 | ケイマン ケミカル カンパニー， インコーポレーテッド | ジフルオロラクタムアナログを合成する方法 |
| EP3021879A2 (de) | 2013-07-19 | 2016-05-25 | Cayman Chemical Company, Incorporated | Verfahren, systeme und zusammensetzungen zur förderung der knochenwachstums |
-
1975
- 1975-06-27 DE DE19752528664 patent/DE2528664A1/de not_active Withdrawn
-
1976
- 1976-06-22 NL NL7606773A patent/NL7606773A/xx not_active Application Discontinuation
- 1976-06-22 ES ES449095A patent/ES449095A1/es not_active Expired
- 1976-06-24 LU LU75235A patent/LU75235A1/xx unknown
- 1976-06-24 SE SE7607331A patent/SE7607331L/xx unknown
- 1976-06-24 CH CH809976A patent/CH623809A5/de not_active IP Right Cessation
- 1976-06-25 IL IL49916A patent/IL49916A0/xx unknown
- 1976-06-25 ZA ZA763802A patent/ZA763802B/xx unknown
- 1976-06-25 AT AT0467976A patent/AT365575B/de active
- 1976-06-25 DK DK287476A patent/DK287476A/da unknown
- 1976-06-25 GB GB26564/76A patent/GB1553595A/en not_active Expired
- 1976-06-26 JP JP51075954A patent/JPS525764A/ja active Pending
- 1976-06-28 BE BE168390A patent/BE843505A/xx not_active IP Right Cessation
- 1976-06-28 FR FR7619563A patent/FR2316943A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK287476A (da) | 1976-12-28 |
| ATA467976A (de) | 1981-06-15 |
| JPS525764A (en) | 1977-01-17 |
| CH623809A5 (en) | 1981-06-30 |
| IL49916A0 (en) | 1976-08-31 |
| BE843505A (fr) | 1976-12-28 |
| NL7606773A (nl) | 1976-12-29 |
| FR2316943A1 (fr) | 1977-02-04 |
| DE2528664A1 (de) | 1977-01-13 |
| LU75235A1 (de) | 1977-03-16 |
| FR2316943B1 (de) | 1978-11-03 |
| GB1553595A (en) | 1979-09-26 |
| AT365575B (de) | 1982-01-25 |
| ZA763802B (en) | 1977-05-25 |
| SE7607331L (sv) | 1976-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES449095A1 (es) | Procedimiento para la preparacion de pirrolidonas. | |
| ES8707724A1 (es) | Un procedimiento para preparar laudanos | |
| CA934758A (en) | Process for the preparation of unsymmetrical 1,4-dihydropyridine 3,5-dicarboxylates | |
| GB1509860A (en) | Process for the manufacture of carbodiimides | |
| HUT49125A (en) | Process for producing new 2-thiazolidinone derivatives and pharmaceutical compositions containing them | |
| GR3003638T3 (de) | ||
| JPS5227734A (en) | Process for preparation of 2,6-dichloro- 4-methylphenol | |
| JPS5247506A (en) | Nitrogen-containing powder-sintered high speed steel | |
| JPS52248A (en) | Process for preparing omega-aminoalkoxy biphenyls and their acid adducts | |
| EP0118732A3 (en) | An anthracycline compound, a process for the production thereof, a pharmaceutical composition containing the same and its use as a medicament | |
| IE43849L (en) | Omega-thienyloxy-prostaglandins. | |
| PT80883A (en) | Process for the preparation of 1,3-dihydro-4-pyridoyl-2h-imidazol-2-ones | |
| JPS51143678A (en) | A process for preparing carbostyril derivatives | |
| JPS51149210A (en) | Process for preparation of tetrafluoroethylene oligomers | |
| JPS5242867A (en) | Process for preparation of 17alpha -(3-hydroxypropyl)- 17beta-hydroxy-androsto- 4 -ene-3-one | |
| DE3572668D1 (en) | Anthracycline derivatives, a process for the production thereof, a pharmaceutical composition containing the same and their use as medicaments | |
| ES8203087A1 (es) | Procedimiento para la obtencion de imidazolil-indeno-tiofe- nos | |
| JPS51148697A (en) | Process for production of anhydrous al fluoride | |
| ES400327A2 (es) | Procedimiento para la produccion de 6 - fenil - 4h - s - triazolo - (4, 3 - a) (1,4) - benzodiacepinas. | |
| JPS5223086A (en) | Novel method of preparing 2,3- dioxopiperazine | |
| JPS5231031A (en) | Process for preparation of substituted phosphonic acid derivatives | |
| JPS51131865A (en) | Process for preparation of novel polycyclic diisocyanates | |
| JPS5247505A (en) | Nitrogen-containing powder-sintered high speed steel | |
| JPS5224912A (en) | Process for producing v-fe oxide used for the production of ferrovanad ium and as an additiv to steel | |
| JPS51122034A (en) | Process for preparation of 4-substituted phenylalkylaldehyde and its d erivatives |