ES449095A1 - Procedimiento para la preparacion de pirrolidonas. - Google Patents
Procedimiento para la preparacion de pirrolidonas.Info
- Publication number
- ES449095A1 ES449095A1 ES449095A ES449095A ES449095A1 ES 449095 A1 ES449095 A1 ES 449095A1 ES 449095 A ES449095 A ES 449095A ES 449095 A ES449095 A ES 449095A ES 449095 A1 ES449095 A1 ES 449095A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- properties
- pyrrolidones
- hand
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000004040 pyrrolidinones Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000003033 spasmogenic effect Effects 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752528664 DE2528664A1 (de) | 1975-06-27 | 1975-06-27 | Pyrrolidone und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449095A1 true ES449095A1 (es) | 1977-12-16 |
Family
ID=5950059
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449095A Expired ES449095A1 (es) | 1975-06-27 | 1976-06-22 | Procedimiento para la preparacion de pirrolidonas. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS525764A (fr) |
| AT (1) | AT365575B (fr) |
| BE (1) | BE843505A (fr) |
| CH (1) | CH623809A5 (fr) |
| DE (1) | DE2528664A1 (fr) |
| DK (1) | DK287476A (fr) |
| ES (1) | ES449095A1 (fr) |
| FR (1) | FR2316943A1 (fr) |
| GB (1) | GB1553595A (fr) |
| IL (1) | IL49916A0 (fr) |
| LU (1) | LU75235A1 (fr) |
| NL (1) | NL7606773A (fr) |
| SE (1) | SE7607331L (fr) |
| ZA (1) | ZA763802B (fr) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE423813B (sv) * | 1976-08-06 | 1982-06-07 | Pfizer | Forfarande for framstellning av 1,5-disubstituerade pyrrolidoner med terapeutiska egenskaper |
| US4772601A (en) * | 1988-01-25 | 1988-09-20 | Hoechst-Roussel Pharmaceuticals, Inc. | 5-Substituted 1-(4-(1-pyrrolidinyl)-2-butynyl)-2-pyrrolidinones, pharmaceutical compositions and use |
| PL356662A1 (en) * | 1999-12-22 | 2004-06-28 | Pfizer Products Inc. | Ep4 receptor selective agonists in the treatment of osteoporosis |
| AU2001290250A1 (en) * | 2000-09-21 | 2002-04-02 | Ono Pharmaceutical Co. Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
| NZ525164A (en) | 2000-11-27 | 2005-04-29 | Pfizer Prod Inc | EP4 receptor selective agonists in the treatment of osteoporosis |
| ES2254726T3 (es) | 2001-07-16 | 2006-06-16 | F. Hoffmann-La Roche Ag | Analogos de prostaglandina como agonistas receptores de ep4. |
| EP1408961B1 (fr) | 2001-07-16 | 2007-07-11 | F. Hoffmann-La Roche Ag | Derives de pyrrolidone comme antagonistes de prostanoide |
| CN101921220B (zh) | 2001-07-23 | 2013-05-22 | 小野药品工业株式会社 | 治疗与骨质损失有关的疾病的含有ep4激动剂作为活性成分的药物组合物 |
| WO2003077910A1 (fr) * | 2002-03-18 | 2003-09-25 | Pfizer Products Inc. | Procedes de traitement au moyen d'agonistes selectifs du recepteur ep4 |
| US6573294B1 (en) | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
| BRPI0406717A (pt) | 2003-01-10 | 2005-12-20 | Hoffmann La Roche | Composto, composição farmacêutica que compreende o mesmo, método de tratamento de uma enfermidade em um mamìfero, utilização do composto e processo para a sua produção |
| US7179820B2 (en) | 2003-06-06 | 2007-02-20 | Allergan, Inc. | Piperidinyl prostaglandin E analogs |
| HUE031885T2 (en) | 2012-07-19 | 2017-08-28 | Cayman Chemical Co Inc | Difluoro lactam preparations for EP4-mediated osteo-related diseases and conditions |
| ES2635635T3 (es) | 2013-03-15 | 2017-10-04 | Cayman Chemical Company, Incorporated | Compuestos de difluorolactama como agonistas selectivos del receptor EP4 para su uso en el tratamiento de enfermedades y afecciones mediadas por EP4 |
| WO2014144500A2 (fr) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Procédés de synthèse d'un analogue difluorolactam |
| US9676712B2 (en) | 2013-03-15 | 2017-06-13 | Cayman Chemical Company, Inc. | Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions |
| KR20160048054A (ko) | 2013-07-19 | 2016-05-03 | 카이맨 케미칼 컴파니 인코포레이티드 | 골 성장의 촉진을 위한 방법, 시스템 및 조성물 |
-
1975
- 1975-06-27 DE DE19752528664 patent/DE2528664A1/de not_active Withdrawn
-
1976
- 1976-06-22 ES ES449095A patent/ES449095A1/es not_active Expired
- 1976-06-22 NL NL7606773A patent/NL7606773A/xx not_active Application Discontinuation
- 1976-06-24 SE SE7607331A patent/SE7607331L/xx unknown
- 1976-06-24 LU LU75235A patent/LU75235A1/xx unknown
- 1976-06-24 CH CH809976A patent/CH623809A5/de not_active IP Right Cessation
- 1976-06-25 GB GB26564/76A patent/GB1553595A/en not_active Expired
- 1976-06-25 IL IL49916A patent/IL49916A0/xx unknown
- 1976-06-25 DK DK287476A patent/DK287476A/da unknown
- 1976-06-25 AT AT0467976A patent/AT365575B/de active
- 1976-06-25 ZA ZA763802A patent/ZA763802B/xx unknown
- 1976-06-26 JP JP51075954A patent/JPS525764A/ja active Pending
- 1976-06-28 BE BE168390A patent/BE843505A/fr not_active IP Right Cessation
- 1976-06-28 FR FR7619563A patent/FR2316943A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2316943A1 (fr) | 1977-02-04 |
| GB1553595A (en) | 1979-09-26 |
| JPS525764A (en) | 1977-01-17 |
| IL49916A0 (en) | 1976-08-31 |
| LU75235A1 (fr) | 1977-03-16 |
| FR2316943B1 (fr) | 1978-11-03 |
| AT365575B (de) | 1982-01-25 |
| BE843505A (fr) | 1976-12-28 |
| DK287476A (da) | 1976-12-28 |
| CH623809A5 (en) | 1981-06-30 |
| ZA763802B (en) | 1977-05-25 |
| DE2528664A1 (de) | 1977-01-13 |
| NL7606773A (nl) | 1976-12-29 |
| ATA467976A (de) | 1981-06-15 |
| SE7607331L (sv) | 1976-12-28 |
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