ES451513A2 - Procedure for the preparation of eteres and ketones 2-carbalcoxyamino-bencimidazolil-5 (6) -fenilicos substituted with basic radicals. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of eteres and ketones 2-carbalcoxyamino-bencimidazolil-5 (6) -fenilicos substituted with basic radicals. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES451513A2 ES451513A2 ES451513A ES451513A ES451513A2 ES 451513 A2 ES451513 A2 ES 451513A2 ES 451513 A ES451513 A ES 451513A ES 451513 A ES451513 A ES 451513A ES 451513 A2 ES451513 A2 ES 451513A2
- Authority
- ES
- Spain
- Prior art keywords
- formula
- carbon atoms
- radical
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000002576 ketones Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- 150000003254 radicals Chemical class 0.000 abstract 3
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- -1 alcohol radical Chemical class 0.000 abstract 2
- JWYUFVNJZUSCSM-UHFFFAOYSA-N 2-aminobenzimidazole Chemical class C1=CC=C2NC(N)=NC2=C1 JWYUFVNJZUSCSM-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical compound [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000003158 alcohol group Chemical group 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000004657 carbamic acid derivatives Chemical class 0.000 abstract 1
- 150000004651 carbonic acid esters Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- BRNULMACUQOKMR-UHFFFAOYSA-N thiomorpholine Chemical group C1CSCCN1 BRNULMACUQOKMR-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Improvements introduced in the object of main patent no. 440,713, applied for on September 4, 1975, by: "Procedure for the preparation of 2-carbalkoxyamino-benzimidazolyl-5 (6) -phenyl ketones substituted with basic radicals", of the formula (1) **(See formula)** where R3 signifies alcohol with 1 to 4 carbon atoms; X means oxygen, sulfur or (see formula); Y means an alcohol group with 1 to 4 straight or branched chain carbon atoms; and R1 as well as R2 means an alcoholic radical with 1 to 4 carbon atoms, the two radicals R1 and R2 being able to signify, together with the nitrogen atom that carries them, also the pyrrolidine, piperidine, morpholino or thiomorpholine rings, characterized in that it is made react a 2-amino-benzimidazole derivative of the formula (2) **(See formula)** in which R1, R2, X and Y have the meanings indicated for formula (1), with a strong base, with a carbonic acid ester of formula (3) **(See formula)** wherein R1 and R4, independently of one another, signify a lower alcohol radical of 1 to 4 carbon atoms, the phenyl radical or the para-nitrophenyl radical, excluding water, and because the carbamate salts obtained are transformed if desired in the free compounds of formula (1), by adding a base. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752541741 DE2541741A1 (en) | 1975-09-19 | 1975-09-19 | (2)-Carbalkoxyamino-benzimidazolyl-phenyl-ethers and-ketones - are antiparasitics having anthelmintic properties, esp. against ankylostomae (NL220377) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES451513A2 true ES451513A2 (en) | 1977-11-01 |
Family
ID=5956857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES451513A Expired ES451513A2 (en) | 1975-09-19 | 1976-09-14 | Procedure for the preparation of eteres and ketones 2-carbalcoxyamino-bencimidazolil-5 (6) -fenilicos substituted with basic radicals. (Machine-translation by Google Translate, not legally binding) |
Country Status (12)
| Country | Link |
|---|---|
| DE (1) | DE2541741A1 (en) |
| DK (1) | DK420076A (en) |
| EG (1) | EG12307A (en) |
| ES (1) | ES451513A2 (en) |
| FI (1) | FI762655A7 (en) |
| GR (1) | GR61184B (en) |
| IT (1) | IT1068314B (en) |
| LU (1) | LU75814A1 (en) |
| NL (1) | NL7610189A (en) |
| NO (1) | NO763194L (en) |
| PT (1) | PT65610B (en) |
| SE (1) | SE7610312L (en) |
-
1975
- 1975-09-19 DE DE19752541741 patent/DE2541741A1/en active Pending
-
1976
- 1976-09-11 EG EG553/76A patent/EG12307A/en active
- 1976-09-14 NL NL7610189A patent/NL7610189A/en unknown
- 1976-09-14 ES ES451513A patent/ES451513A2/en not_active Expired
- 1976-09-16 SE SE7610312A patent/SE7610312L/en unknown
- 1976-09-16 FI FI762655A patent/FI762655A7/fi not_active Application Discontinuation
- 1976-09-16 LU LU75814A patent/LU75814A1/xx unknown
- 1976-09-17 IT IT27368/76A patent/IT1068314B/en active
- 1976-09-17 PT PT65610A patent/PT65610B/en unknown
- 1976-09-17 NO NO763194A patent/NO763194L/en unknown
- 1976-09-17 DK DK420076A patent/DK420076A/en unknown
- 1976-09-18 GR GR51721A patent/GR61184B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EG12307A (en) | 1982-09-30 |
| SE7610312L (en) | 1977-03-20 |
| GR61184B (en) | 1978-10-05 |
| NL7610189A (en) | 1977-03-22 |
| PT65610A (en) | 1976-10-01 |
| PT65610B (en) | 1978-05-10 |
| DE2541741A1 (en) | 1977-03-31 |
| FI762655A7 (en) | 1977-03-20 |
| LU75814A1 (en) | 1977-05-13 |
| NO763194L (en) | 1977-03-22 |
| DK420076A (en) | 1977-03-20 |
| IT1068314B (en) | 1985-03-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES467288A1 (en) | N-(substituted-aminoalkyl)-2-oxo-1-pyrrolidineacetamides | |
| ES378367A1 (en) | Process for the preparation of pyrimidine nucleosides | |
| ES394370A1 (en) | Pharmacologically active 3-piperazinyl-carbonyloxy-2-pyridyl-isoindolin-1-ones | |
| ES8604543A1 (en) | Piperazine derivatives with anticholinergic and/or antihistaminic activity | |
| ES443563A1 (en) | 2-methoxy-benzamide derivatives | |
| ES419337A1 (en) | Process for the preparation of thiazole-sulphenamides | |
| ES423232A1 (en) | 2-phenylamino-imidazolines-(2) | |
| ES420493A1 (en) | Process for the preparation of thiazolesulphenamides | |
| ES440713A1 (en) | Anthelmintically active basically substituted 2-carbalkoxy-amino-benzimidazolyl-5(6)-phenyl ethers and -ketones | |
| ES423699A1 (en) | 3-oxyiminomethyl-cephalosporins | |
| ES446444A1 (en) | Process for the preparation of carbonyl alpha-perfluoro derivatives | |
| ES444036A1 (en) | Process for the preparation of 2-2-thienyl-ethylamine and derivatives thereof | |
| ES388013A1 (en) | N-(2-formylpropylthio(2))-imides | |
| ES435351A1 (en) | 1-(3-phenylpropyl)-4-furoylpiperazine derivatives | |
| ES434955A1 (en) | Derivatives of 5-hydroxy-2,3-dihydro-1h-dibenzo(2,3:6,7)thiepino and oxepino-(4,5-c)pyrrole methods for their preparation and compositions containing them | |
| ES465761A1 (en) | Manufacture of 3-halosulfonylthiophene-carboxylic acid compounds | |
| ES445922A1 (en) | PROCEDURE FOR PREPARING BENZOFURANONE DERIVATIVES. | |
| ES468143A1 (en) | Production of phosphoric acid esters of n-hydroxyalkyl perfluoroalkane sulphonamides | |
| ES465366A2 (en) | 2-methoxybenzamides | |
| ES483796A1 (en) | A PROCEDURE FOR THE PREPARATION OF ACID-PENAM-3-CARBOXYL DERIVATIVES. | |
| ES454098A1 (en) | Procedure to produce argininamids and their salts. (Machine-translation by Google Translate, not legally binding) | |
| ES8302706A1 (en) | Phenylquinolizidine | |
| ES438446A1 (en) | Spiro-heterocyclic compounds and their use in pharmaceutical compositions | |
| ES469913A1 (en) | 6,11-dihydrodibenzo-(b. e.)-thiepin-11-one-3-aldehyde and 3-acetal derivatives | |
| ES428624A1 (en) | Procedure for the preparation of pyrimidine derivatives. (Machine-translation by Google Translate, not legally binding) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170706 |