ES451865A1 - Procedimiento para la preparacion de nuevos 4-hidroxi-2h-na-fto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos. - Google Patents

Procedimiento para la preparacion de nuevos 4-hidroxi-2h-na-fto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.

Info

Publication number: ES451865A1
Authority: ES; Spain
Prior art keywords: methyl; thiazolyl; pyridyl; ethyl; salts
Prior art date: 1974-11-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES451865A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim Pharma GmbH and Co KG

Original Assignee

Dr Karl Thomae GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-11-08

Filing date

1976-09-25

Publication date

1977-11-01

1974-11-08 Priority claimed from DE19742452996 external-priority patent/DE2452996A1/de

1975-09-03 Priority claimed from DE2539112A external-priority patent/DE2539112C2/de

1976-09-25 Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH

1977-11-01 Publication of ES451865A1 publication Critical patent/ES451865A1/es

Status Expired legal-status Critical Current

Links

150000003839 salts Chemical class 0.000 title abstract 3
-1 4-methyl-2-pyridyl Chemical group 0.000 abstract 20
150000001875 compounds Chemical class 0.000 abstract 2
125000004520 1,3,4-thiadiazolyl group Chemical group 0.000 abstract 1
125000004198 2-fluorophenyl group Chemical group [H]C1=C([H])C(F)=C(*)C([H])=C1[H] 0.000 abstract 1
125000004204 2-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C(OC([H])([H])[H])C([H])=C1[H] 0.000 abstract 1
125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
125000006275 3-bromophenyl group Chemical group [H]C1=C([H])C(Br)=C([H])C(*)=C1[H] 0.000 abstract 1
125000004179 3-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(Cl)=C1[H] 0.000 abstract 1
125000004180 3-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(F)=C1[H] 0.000 abstract 1
125000004207 3-methoxyphenyl group Chemical group [H]C1=C([H])C(*)=C([H])C(OC([H])([H])[H])=C1[H] 0.000 abstract 1
125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
230000002776 aggregation Effects 0.000 abstract 1
238000004220 aggregation Methods 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
150000007529 inorganic bases Chemical class 0.000 abstract 1
125000000040 m-tolyl group Chemical group [H]C1=C([H])C(*)=C([H])C(=C1[H])C([H])([H])[H] 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
231100000252 nontoxic Toxicity 0.000 abstract 1
230000003000 nontoxic effect Effects 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000004307 pyrazin-2-yl group Chemical group [H]C1=C([H])N=C(*)C([H])=N1 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)

ES451865A 1974-11-08 1976-09-25 Procedimiento para la preparacion de nuevos 4-hidroxi-2h-na-fto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos. Expired ES451865A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19742452996 DE2452996A1 (de)	1974-11-08	1974-11-08	Neue 4-hydroxy-2h-naphtho- eckige klammer auf 2,1-e eckige klammer zu -1,2thiazin-3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2539112A DE2539112C2 (de)	1975-09-03	1975-09-03	4-Hydroxy-2H-naphtho[2,1-e]-1,2-thiazin-3-carboxamid-1,1-dioxide, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number	Publication Date
ES451865A1 true ES451865A1 (es)	1977-11-01

Family

ID=25767938

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
ES442074A Expired ES442074A1 (es)	1974-11-08	1975-10-24	Procedimiento para la preparacion de nuevos 4-hidroxi-2h- nafto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.
ES451865A Expired ES451865A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-na-fto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.
ES451868A Expired ES451868A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-nafto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.
ES451869A Expired ES451869A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-naf-to-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.
ES451867A Expired ES451867A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-nafto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
ES442074A Expired ES442074A1 (es)	1974-11-08	1975-10-24	Procedimiento para la preparacion de nuevos 4-hidroxi-2h- nafto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
ES451868A Expired ES451868A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-nafto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.
ES451869A Expired ES451869A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-naf-to-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.
ES451867A Expired ES451867A1 (es)	1974-11-08	1976-09-25	Procedimiento para la preparacion de nuevos 4-hidroxi-2h-nafto-(2, 1-e)-1, 2-tiazin-3-carboxamido-1, 1-dioxidos.

Country Status (26)

Country	Link
US (1)	US3992535A (es)
JP (1)	JPS51125292A (es)
AT (1)	AT345847B (es)
BG (1)	BG32715A3 (es)
CA (1)	CA1048025A (es)
CH (4)	CH618976A5 (es)
CS (1)	CS185583B2 (es)
DD (1)	DD122823A5 (es)
DK (1)	DK140533B (es)
ES (5)	ES442074A1 (es)
FI (1)	FI60011C (es)
FR (1)	FR2290211A1 (es)
GB (1)	GB1485910A (es)
HU (1)	HU174520B (es)
IE (1)	IE42930B1 (es)
IL (1)	IL48439A (es)
LU (1)	LU73748A1 (es)
NL (1)	NL7512271A (es)
NO (1)	NO143317C (es)
NZ (1)	NZ179178A (es)
PH (1)	PH11809A (es)
PL (1)	PL107647B1 (es)
RO (1)	RO68500A (es)
SE (1)	SE420605B (es)
SU (1)	SU575027A3 (es)
YU (1)	YU281075A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2704485A1 (de) *	1977-02-03	1978-08-10	Thomae Gmbh Dr K	Neue 2,5-dihydro-1,2-thiazino eckige klammer auf 5,6-b eckige klammer zu indol-3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
IN158333B (es) *	1981-08-03	1986-10-18	Pfizer
EP0082217A1 (de) *	1981-12-23	1983-06-29	Ciba-Geigy Ag	Neue Ammoniumsalze, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Verwendung
US4683306A (en) *	1984-07-13	1987-07-28	Yuhan Corporation Co., Ltd.	Process for the preparation of 3,4-dihydro-2-substituted-2H-1,2-thiazine-carboxylic acid 1,1-dioxide derivatives
WO2012004338A1 (en) *	2010-07-09	2012-01-12	Active Biotech Ab	Method for manufacturing of quinoline-3-carboxamides
CN103275035B (zh) *	2013-06-28	2014-11-26	安徽中医学院	苯并噻嗪类化合物、其制备方法及其抗肿瘤用途
USD825997S1 (en)	2018-03-22	2018-08-21	Remson Concepts, Inc	Stackable serving tray
USD835467S1 (en)	2018-07-23	2018-12-11	Remson Concepts, Inc.	Stackable serving tray

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1090252A (en) *	1965-04-13	1967-11-08	Ici Ltd	Dibenzothiazine derivatives

1975
- 1975-10-07 AT AT764875A patent/AT345847B/de not_active IP Right Cessation
- 1975-10-20 NL NL7512271A patent/NL7512271A/xx not_active Application Discontinuation
- 1975-10-24 ES ES442074A patent/ES442074A1/es not_active Expired
- 1975-10-29 SU SU7502183260A patent/SU575027A3/ru active
- 1975-10-29 US US05/626,623 patent/US3992535A/en not_active Expired - Lifetime
- 1975-10-31 GB GB45407/75A patent/GB1485910A/en not_active Expired
- 1975-11-03 BG BG031394A patent/BG32715A3/xx unknown
- 1975-11-03 RO RO7583800A patent/RO68500A/ro unknown
- 1975-11-04 CS CS7500007427A patent/CS185583B2/cs unknown
- 1975-11-05 CH CH1433075A patent/CH618976A5/de not_active IP Right Cessation
- 1975-11-05 HU HU75TO1014A patent/HU174520B/hu unknown
- 1975-11-05 PH PH17738A patent/PH11809A/en unknown
- 1975-11-06 LU LU73748A patent/LU73748A1/xx unknown
- 1975-11-06 YU YU02810/75A patent/YU281075A/xx unknown
- 1975-11-06 DD DD189304A patent/DD122823A5/xx unknown
- 1975-11-07 DK DK503075AA patent/DK140533B/da not_active IP Right Cessation
- 1975-11-07 CA CA239,175A patent/CA1048025A/en not_active Expired
- 1975-11-07 SE SE7512534A patent/SE420605B/xx unknown
- 1975-11-07 FI FI753124A patent/FI60011C/fi not_active IP Right Cessation
- 1975-11-07 PL PL1975184576A patent/PL107647B1/pl unknown
- 1975-11-07 JP JP50133182A patent/JPS51125292A/ja active Pending
- 1975-11-07 FR FR7534140A patent/FR2290211A1/fr active Granted
- 1975-11-07 IL IL48439A patent/IL48439A/xx unknown
- 1975-11-07 NZ NZ179178A patent/NZ179178A/xx unknown
- 1975-11-07 NO NO753738A patent/NO143317C/no unknown
- 1975-11-07 IE IE2439/79A patent/IE42930B1/en unknown
1976
- 1976-09-25 ES ES451865A patent/ES451865A1/es not_active Expired
- 1976-09-25 ES ES451868A patent/ES451868A1/es not_active Expired
- 1976-09-25 ES ES451869A patent/ES451869A1/es not_active Expired
- 1976-09-25 ES ES451867A patent/ES451867A1/es not_active Expired
1980
- 1980-03-13 CH CH199080A patent/CH626080A5/de not_active IP Right Cessation
- 1980-03-13 CH CH198980A patent/CH628041A5/de not_active IP Right Cessation
- 1980-03-13 CH CH198880A patent/CH628040A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
CH628041A5 (de)	1982-02-15
GB1485910A (en)	1977-09-14
NO143317B (no)	1980-10-06
FI60011B (fi)	1981-07-31
CH618976A5 (es)	1980-08-29
US3992535A (en)	1976-11-16
JPS51125292A (en)	1976-11-01
PH11809A (en)	1978-07-10
PL107647B1 (pl)	1980-02-29
IE42930L (en)	1976-05-08
LU73748A1 (es)	1977-06-03
ES451869A1 (es)	1977-11-01
ES451868A1 (es)	1977-11-01
RO68500A (ro)	1981-06-21
ES442074A1 (es)	1977-03-16
FR2290211B1 (es)	1980-05-09
CH628040A5 (de)	1982-02-15
NO753738L (es)	1976-05-11
DK140533C (es)	1980-02-18
DD122823A5 (es)	1976-11-05
NL7512271A (nl)	1976-05-11
IE42930B1 (en)	1980-11-19
IL48439A0 (en)	1976-01-30
SU575027A3 (ru)	1977-09-30
SE7512534L (sv)	1976-05-10
DK503075A (es)	1976-05-09
FR2290211A1 (fr)	1976-06-04
DK140533B (da)	1979-09-24
ES451867A1 (es)	1977-11-01
YU281075A (en)	1982-05-31
SE420605B (sv)	1981-10-19
NZ179178A (en)	1978-04-28
CS185583B2 (en)	1978-10-31
AT345847B (de)	1978-10-10
NO143317C (no)	1981-01-14
FI753124A7 (es)	1976-05-09
FI60011C (fi)	1981-11-10
ATA764875A (de)	1978-02-15
BG32715A3 (bg)	1982-09-15
HU174520B (hu)	1980-01-28
CH626080A5 (es)	1981-10-30
IL48439A (en)	1978-12-17
CA1048025A (en)	1979-02-06

Publication	Publication Date	Title
AU2007281230B2 (en)	2011-09-08	Smac peptidomimetics useful as IAP inhibitors
CA1167841A (en)	1984-05-22	Derivatives of 1,2,5-thiadiazole-1-oxide and 1,1- dioxides as histamine h.sub.2-antagonists
IE42930L (en)	1976-05-08	3-ARYLAMINOCARBONYL-4-HYDROXY-2H-NAPHTHO [2,1-e]-1,¹2-THIAZINE-1, 1-DIOXIDES
US4394508A (en)	1983-07-19	Chemical compounds
IE38839L (en)	1974-08-20	Pyridazinyl, pyrimidinyl, pyrazinyl and pyridyl compounds
ZA897760B (en)	1991-06-26	Oxime ether derivatives,their preparation and fungicides containing these derivatives
KR920021522A (ko)	1992-12-18	피페라진 유도체
LU90711I2 (fr)	2001-03-05	5-(4-/2-(N-m-thyl-n-(2-pyridyl)amino)-thoxy/benzyl)-2,4-thiazolidinedione ou ses sels et d-riv-s pharmaceutiquement acceptables en particulier son sel mal-ate ou ses solvates pharmaceutiquement acceptables
SE7614620L (sv)	1977-06-30	Farmakologiskt aktiva foreningar
PH23146A (en)	1989-05-11	4-substituted benzoyloxy-n-substituted-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxides having anti-arthritic activity
IE820054L (en)	1982-07-15	Benzothiazine dioxide anti-inflammatory agents
GB1505932A (en)	1978-04-05	Preparation of benzothiazine-1,1-dioxide derivatives
AU576269B2 (en)	1988-08-18	Heterocyclic histamine h2-receptor antagonists
BG41307A3 (bg)	1987-05-15	Метод за получаване на 3,4- дихидро- 2- метил- 4- оксо- 2н- 1,2-бензотиазин-3-карбоновокисел-1,1-двуокис и неговите 2- пиридил и 2 тиазолилови производни
DE3776590D1 (de)	1992-03-19	2-pyridyl-penem-verbindungen.
DE3275092D1 (en)	1987-02-19	4-aryl or heteroaryl thio-2-oxo-1-azetidinesulfonic acid salts and process for their preparation
US4471122A (en)	1984-09-11	Thiadiazole histamine H2 -antagonists
ES436200A1 (es)	1977-01-16	Procedimiento para preparar 2-(aminofenilimino)-3-aza-1-tia-cicloalcanos.
US3862319A (en)	1975-01-21	Benzothiazine dioxides as anti-thromobotic agents
FR2153206A2 (en)	1973-05-04	Phenyl - dihydroimidazo (2,1-b) thiazole derivs - anthelmintics
AP2002002673A0 (en)	2002-12-31	Thiazolidinedione salt for the treatment of diabetes mellitus.
AP1785A (en)	2007-10-04	Tartrate salt of thiazolidinedione derivative.
DE60124119D1 (de)	2006-12-07	Ein thiazolidindionderivat und seine verwendung als antidiabetikum
ES469110A1 (es)	1978-11-16	Procedimiento para la preparacion de nuevos 2,5-dihidro-1,2-tiazino (5,6-b)indol-3-carboxamido-1,1-dioxidos.
GB1212326A (en)	1970-11-11	New 5-nitro-4-thiazoline-3-acetamide compounds and methods for their production