ES452447A1 - Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente. - Google Patents

Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente.

Info

Publication number
ES452447A1
ES452447A1 ES452447A ES452447A ES452447A1 ES 452447 A1 ES452447 A1 ES 452447A1 ES 452447 A ES452447 A ES 452447A ES 452447 A ES452447 A ES 452447A ES 452447 A1 ES452447 A1 ES 452447A1
Authority
ES
Spain
Prior art keywords
therapeutic agent
dry eye
therapeutic system
treating aqueous
proportional amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES452447A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ES452447A1 publication Critical patent/ES452447A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Mejoras introducidas en un órgano de inserción ocular para tratar el ojo seco de secreción lacrimal deficiente, comprendiendo dicho órgano de inserción un agente terapéutico confinado dentro de un cuerpo de polímero de tamaño y forma idóneos para ser introducido y retenido en el fondo de la cavidad ocular y que cuando se coloca en el ojo libera el agente terapéutico en forma continua durante un periodo de tiempo prolongado y en una cantidad proporcional controlada, caracterizadas dichas mejoras por el hecho de que el agente terapéutico es una disolución biológicamente compatible, y la cantidad proporcional es suficiente para inducir un flujo acuoso endógeno significativo a la película lagrimal.
ES452447A 1975-10-28 1976-10-15 Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente. Expired ES452447A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/625,918 US3991759A (en) 1975-10-28 1975-10-28 Method and therapeutic system for treating aqueous deficient dry eye

Publications (1)

Publication Number Publication Date
ES452447A1 true ES452447A1 (es) 1978-02-16

Family

ID=24508173

Family Applications (1)

Application Number Title Priority Date Filing Date
ES452447A Expired ES452447A1 (es) 1975-10-28 1976-10-15 Mejoras introducidas en un organo de insercion ocular para tratar el ojo seco de secrecion lacrimal deficiente.

Country Status (18)

Country Link
US (1) US3991759A (es)
JP (1) JPS5255291A (es)
AR (1) AR213293A1 (es)
AT (1) AT353412B (es)
AU (1) AU502717B2 (es)
BE (1) BE847686A (es)
CA (1) CA1070614A (es)
DE (1) DE2648737A1 (es)
DK (1) DK487876A (es)
ES (1) ES452447A1 (es)
FR (1) FR2329261A1 (es)
GB (1) GB1526476A (es)
IE (1) IE44351B1 (es)
IL (1) IL50651A (es)
IT (1) IT1070272B (es)
NL (1) NL7611911A (es)
SE (1) SE7611944L (es)
ZA (1) ZA765799B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177256A (en) * 1973-04-25 1979-12-04 Alza Corporation Osmotic bursting drug delivery device
US4207890A (en) * 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4190642A (en) * 1978-04-17 1980-02-26 Alza Corporation Ocular therapeutic system for dispensing a medication formulation
US4287175A (en) * 1978-06-22 1981-09-01 Merck & Co., Inc. Contact lens wetting agents
US4868154A (en) * 1986-02-19 1989-09-19 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with melanocyte stimulating hormones
US4744980A (en) * 1986-04-28 1988-05-17 Holly Frank J Ophthalmic solution for treatment of dry eye syndrome
US4883658A (en) * 1986-04-28 1989-11-28 Holly Frank J Ophthalmic solution for treatment of dry-eye syndrome
US5660851A (en) * 1989-12-26 1997-08-26 Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem Ocular inserts
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
US5290572A (en) * 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
DE19549506C2 (de) * 1995-03-07 1998-07-30 Richard Prof Dr Sueverkruep Darreichungsform zur äußerlichen Applikation und Verfahren zur Herstellung derselben
US5696166A (en) * 1995-10-31 1997-12-09 Yanni; John M. Compositions containing hydroxyeicosatetraenoic acid derivatives and methods of use in treating dry eye disorders
ZA989513B (en) 1997-10-21 1999-04-21 Alcon Lab Inc Compositions containing histamine H2 agonists and methods of use in treating dry eye
AU2183800A (en) 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Prostaglandin e agonists for treatment of dry eye
AU2183900A (en) 1998-12-24 2000-07-31 Alcon Laboratories, Inc. Ep4 receptor agonists for treatment of dry eye
DE60019322T2 (de) 1999-11-09 2005-09-08 Alcon Inc. Heteroatomunterbrochene analoge von15-hydroxyeicosatetraensäure und verfahren zu deren verwendung
DE60007547T2 (de) 1999-11-09 2004-06-17 Alcon, Inc. 15-hydroxyeicosatetraensäure verwandte verbindungen und anwendungsverfahren
US6331644B1 (en) 1999-11-09 2001-12-18 Alcon Universal Ltd. 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use
WO2001034550A2 (en) 1999-11-09 2001-05-17 Alcon Universal Ltd. 15-hydroxyeicosatetraenoic acid analogs with enhanced metabolic stability and methods of their use in treating dry eye disorders
DK1228032T3 (da) 1999-11-09 2004-11-01 Alcon Inc Præparater, som indeholder hydroxyicosatetraensyrederivater, og fremgangsmåder til anvendelse ved behandling af öjentörhedslidelser
ATE258791T1 (de) 1999-11-09 2004-02-15 Alcon Inc Lipoxin-a4 und deren analoge zur behandlung von trockenen augen
US6458854B2 (en) 1999-11-09 2002-10-01 Alcon Universal Ltd. Phospholipids of hydroxyeicosatetraenoic acid-like derivatives and methods of use
US6803385B2 (en) 1999-11-09 2004-10-12 Alcon, Inc. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
US6255343B1 (en) 1999-11-09 2001-07-03 Alcon Universal Ltd. 2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
BR0015402A (pt) 1999-11-09 2002-06-25 Alcon Inc Derivados de ácido 15-hidroxieicosatetraenóico de cadeia Èmega modificada e métodos de seu uso para o tratamento de olho seco
AU1226001A (en) 1999-11-09 2001-06-06 Alcon Universal Limited Phospholipids of hydroxyeicosatetraenoic acid-like derivatives
US6552084B2 (en) 1999-11-09 2003-04-22 Alcon Universal Ltd. Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
KR20020050240A (ko) 1999-11-09 2002-06-26 구이도 콜러, 스테판 바슬러 하이드록시에이코사테트라에노에이트 염, 조성물 및 안구건조증 치료에서의 사용 방법
PT1228030E (pt) 1999-11-09 2005-08-31 Alcon Inc Derivados benzenoidicos do acido 15-hidroxieicosatetraenoico e metodos para a sua utilizacao no tratamento das perturbacoes do olho seco
US6576663B2 (en) 1999-12-22 2003-06-10 Alcon, Inc. 6-Keto prostaglandin F1α and analogs for treating dry eye
AR031135A1 (es) 2000-10-10 2003-09-10 Upjohn Co Composiciones de antibiotico topico para el tratamiento de infecciones oculares
US20030008853A1 (en) * 2001-05-21 2003-01-09 Alcon, Inc. Method for treating dry eye disorders
US6872382B1 (en) 2001-05-21 2005-03-29 Alcon, Inc. Use of selective PDE IV inhibitors to treat dry eye disorders
US7112588B2 (en) * 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
ATE353667T1 (de) 2001-05-21 2007-03-15 Alcon Inc Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges
BR0209965A (pt) 2001-05-21 2004-04-06 Alcon Inc Uso de inibidores de nf-kappab para tratar distúrbios do olho seco
US6645994B1 (en) 2001-06-01 2003-11-11 Alcon, Inc. Method of treating dry eye disorders
US6750250B1 (en) 2001-07-12 2004-06-15 Alcon, Inc. 11,12-oxidoarachidonic acid derivatives and methods of their use in treating dry eye disorders
AU2003303623A1 (en) * 2002-12-20 2004-07-29 Alcon, Inc. Treatment of dry eye by restoring 15-lipoxygenase activity to ocular surface cells
CN101043884A (zh) * 2004-07-01 2007-09-26 谢彭斯眼科研究公司 用于治疗眼部疾病和病症的组合物和方法
US20090142292A1 (en) * 2007-12-03 2009-06-04 Blackwell Richard I Method For The Mitigation of Symptoms of Dry Eye

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3896819A (en) * 1969-04-01 1975-07-29 Alejandro Zaffaroni IUD having a replenishing drug reservoir
US3664340A (en) * 1969-10-17 1972-05-23 Loran B Morgan Scleral lens with attached tube
US3828777A (en) * 1971-11-08 1974-08-13 Alza Corp Microporous ocular device
US3832458A (en) * 1971-12-06 1974-08-27 River C Foundation Hydrophilic silicone composition and method
US3818909A (en) * 1972-10-25 1974-06-25 F Bratton Eye treatment application devices
US3811444A (en) * 1972-12-27 1974-05-21 Alza Corp Bioerodible ocular device
US3917119A (en) * 1974-11-01 1975-11-04 Bel Art Prod Inc Squeeze type device for dispensing liquid medicaments or the like to a bodily organ

Also Published As

Publication number Publication date
IL50651A0 (en) 1976-12-31
US3991759A (en) 1976-11-16
IL50651A (en) 1979-12-30
IE44351B1 (en) 1981-11-04
JPS5255291A (en) 1977-05-06
CA1070614A (en) 1980-01-29
DK487876A (da) 1977-04-29
FR2329261B1 (es) 1978-11-03
AT353412B (de) 1979-11-12
BE847686A (fr) 1977-02-14
IT1070272B (it) 1985-03-29
AU1899976A (en) 1978-05-04
DE2648737A1 (de) 1977-05-05
ATA801676A (de) 1979-04-15
FR2329261A1 (fr) 1977-05-27
IE44351L (en) 1977-04-28
ZA765799B (en) 1977-09-28
AU502717B2 (en) 1979-08-02
AR213293A1 (es) 1979-01-15
SE7611944L (sv) 1977-04-29
NL7611911A (nl) 1977-05-02
GB1526476A (en) 1978-09-27

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