ES454502A1 - A PROCEDURE FOR THE PREPARATION OF 1,2-BENZOTHIAZIN-3-CARBOXAMIDES. - Google Patents

A PROCEDURE FOR THE PREPARATION OF 1,2-BENZOTHIAZIN-3-CARBOXAMIDES.

Info

Publication number
ES454502A1
ES454502A1 ES454502A ES454502A ES454502A1 ES 454502 A1 ES454502 A1 ES 454502A1 ES 454502 A ES454502 A ES 454502A ES 454502 A ES454502 A ES 454502A ES 454502 A1 ES454502 A1 ES 454502A1
Authority
ES
Spain
Prior art keywords
formula
preparation
carboxamides
benzothiazin
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES454502A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES454502A1 publication Critical patent/ES454502A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/021,2-Thiazines; Hydrogenated 1,2-thiazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

A process for the preparation of 1,2-benzothiazine-3-carboxamides according to the formula ** (see formula) ** And its alkali metal and alkaline earth metal salts in which r is 2-thiazolyl or 2-pyridyl, characterized by contacting an alkali metal or alkaline earth metal salt of a compound according to the formula: ** (see formula) ** With at least one mole of a methylating agent in a solvent inert to the reaction at a temperature of 0 to 100ºC (273 to 373º k) and when it is required to prepare the pharmaceutically acceptable salt. (Machine-translation by Google Translate, not legally binding)
ES454502A 1976-01-12 1976-12-22 A PROCEDURE FOR THE PREPARATION OF 1,2-BENZOTHIAZIN-3-CARBOXAMIDES. Expired ES454502A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64850776A 1976-01-12 1976-01-12

Publications (1)

Publication Number Publication Date
ES454502A1 true ES454502A1 (en) 1977-12-01

Family

ID=24601065

Family Applications (1)

Application Number Title Priority Date Filing Date
ES454502A Expired ES454502A1 (en) 1976-01-12 1976-12-22 A PROCEDURE FOR THE PREPARATION OF 1,2-BENZOTHIAZIN-3-CARBOXAMIDES.

Country Status (15)

Country Link
JP (1) JPS5293777A (en)
AR (1) AR210628A1 (en)
AT (1) AT349483B (en)
CA (1) CA1069894A (en)
CH (1) CH594650A5 (en)
DD (1) DD130145A5 (en)
DK (1) DK579876A (en)
ES (1) ES454502A1 (en)
FI (1) FI63231B (en)
HU (1) HU173509B (en)
LU (1) LU76466A1 (en)
NL (1) NL7614135A (en)
PL (1) PL102554B1 (en)
SE (1) SE421792B (en)
SU (1) SU634672A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN160683B (en) * 1981-06-01 1987-07-25 Pfizer
US4474955A (en) * 1981-06-17 1984-10-02 Vincenzo Iannella Process for preparing 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-[N-(2-pyridinyl)carboxamide]-1,1-dioxide, and its phosphoric ester
IN159273B (en) * 1981-10-05 1987-04-25 Pfizer
DE3217315C2 (en) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Medicinal preparations containing oxicam derivatives
IT1216686B (en) * 1988-04-01 1990-03-08 Chiesi Farma Spa AQUEOUS PHARMACEUTICAL FORMULATIONS OF PIROXICAM AND PROCEDURE FOR THEIR PREPARATION.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides

Also Published As

Publication number Publication date
CA1069894A (en) 1980-01-15
CH594650A5 (en) 1978-01-13
JPS5293777A (en) 1977-08-06
NL7614135A (en) 1977-07-14
LU76466A1 (en) 1977-07-05
FI63231B (en) 1983-01-31
DK579876A (en) 1977-07-13
PL102554B1 (en) 1979-04-30
AR210628A1 (en) 1977-08-31
HU173509B (en) 1979-05-28
AT349483B (en) 1979-04-10
SE7613691L (en) 1977-07-13
FI763680A7 (en) 1977-07-13
SE421792B (en) 1982-02-01
DD130145A5 (en) 1978-03-08
SU634672A3 (en) 1978-11-25
ATA915876A (en) 1978-09-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103