ES455473A1 - Procedimiento de preparacion de un concentrado de factor an-tihemofilico. - Google Patents

Procedimiento de preparacion de un concentrado de factor an-tihemofilico.

Info

Publication number
ES455473A1
ES455473A1 ES455473A ES455473A ES455473A1 ES 455473 A1 ES455473 A1 ES 455473A1 ES 455473 A ES455473 A ES 455473A ES 455473 A ES455473 A ES 455473A ES 455473 A1 ES455473 A1 ES 455473A1
Authority
ES
Spain
Prior art keywords
themophilic
preparation
procedure
factor concentrate
concentrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455473A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RECHERCHES HEMATOLOGIQUES
Original Assignee
RECHERCHES HEMATOLOGIQUES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/653,973 external-priority patent/US4069216A/en
Application filed by RECHERCHES HEMATOLOGIQUES filed Critical RECHERCHES HEMATOLOGIQUES
Publication of ES455473A1 publication Critical patent/ES455473A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

Procedimiento de preparación de un concentrado de factor antihemofílico, denominado factor VIII, caracterizado porque comprende la etapa que consiste en mantener una solución tampón que contiene el Factor VIII y aproximadamente 6% de poliol a una temperatura de aproximadamente0º a 5º hasta que se produce la precipitación.
ES455473A 1976-01-30 1977-01-29 Procedimiento de preparacion de un concentrado de factor an-tihemofilico. Expired ES455473A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/653,973 US4069216A (en) 1975-06-16 1976-01-30 Simplified methods for preparation of very high purity Factor VIII concentrate

Publications (1)

Publication Number Publication Date
ES455473A1 true ES455473A1 (es) 1978-01-01

Family

ID=24623016

Family Applications (1)

Application Number Title Priority Date Filing Date
ES455473A Expired ES455473A1 (es) 1976-01-30 1977-01-29 Procedimiento de preparacion de un concentrado de factor an-tihemofilico.

Country Status (16)

Country Link
JP (1) JPS52102410A (es)
AR (1) AR214625A1 (es)
AT (1) AT354632B (es)
BE (1) BE850852A (es)
BR (1) BR7700554A (es)
CA (1) CA1101332A (es)
DE (1) DE2703620C2 (es)
DK (1) DK146855C (es)
ES (1) ES455473A1 (es)
FR (1) FR2339621A1 (es)
GB (1) GB1557609A (es)
LU (1) LU76652A1 (es)
MX (1) MX5197E (es)
NL (1) NL179290C (es)
NO (1) NO145563C (es)
SE (1) SE442953B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE448945B (sv) * 1979-12-20 1987-03-30 Blombaeck E G B Forfarande for rening och /eller koncentrering av faktor viii-komplexet
AT369263B (de) * 1980-08-27 1982-12-27 Immuno Ag Verfahren zur herstellung eines faktor viii(ahf) -hochkonzentrates
DE3279292D1 (en) * 1981-04-08 1989-01-26 Atomic Energy Authority Uk Blood fractionation improvement
US4382028A (en) * 1982-07-19 1983-05-03 Monsanto Company Separation of plasma proteins from cell culture systems
FR2535173A1 (fr) * 1982-11-03 1984-05-04 Protein Sa Produits obtenus a partir de sang d'animaux d'abattoirs et leur procede d'obtention
FR2603805A1 (fr) * 1986-09-16 1988-03-18 Transfusion Sanguine Assoc Rgl Procede d'inactivation par ozonolyse de micro-organismes contaminants presents dans des materiaux biologiques essentiellement proteiques, les produits obtenus et leurs applications biologiques et analytiques
HRP940645A2 (en) * 1993-10-06 1996-12-31 Immuno Ag Process for virus deactivation in the presence of polyalkylene glycol and the pharmaceutical preparation thus obtained
PL2864026T3 (pl) 2012-06-26 2018-11-30 Swm Luxembourg S A R L Filtracja membranowa z wykorzystaniem niskoenergetycznego separatora zasilania

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL286954A (es) * 1962-01-03
US3652530A (en) * 1967-08-28 1972-03-28 American Nat Red Cross Antihemophilic factor prepared from blood plasma using polyethylene glycol
US3631018A (en) * 1970-05-01 1971-12-28 Baxter Laboratories Inc Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate
US3682881A (en) * 1970-10-02 1972-08-08 Baxter Laboratories Inc Fractionation of plasma using glycine and polyethylene glycol
US3770631A (en) * 1971-06-29 1973-11-06 Baxter Laboratories Inc Clarification of blood serum and plasma
US3839314A (en) * 1971-06-29 1974-10-01 Baxter Laboratories Inc Clarification of blood serum and plasma using block copolymers of ethylene oxide and polyoxypropylene
US4073886A (en) * 1973-01-30 1978-02-14 Baxter Travenol Laboratories, Inc. Blood fractionation process using block copolymers of ethylene oxide and polyoxypropylene
US3893990A (en) * 1973-04-05 1975-07-08 Baxter Laboratories Inc Clarification of blood serum and plasma using a block copolymer of ethylene oxide and polyoxypropylene

Also Published As

Publication number Publication date
NL7700927A (nl) 1977-08-02
SE7700864L (sv) 1977-07-31
CA1101332A (fr) 1981-05-19
BR7700554A (pt) 1977-10-04
SE442953B (sv) 1986-02-10
LU76652A1 (es) 1978-09-13
NL179290C (nl) 1986-08-18
DK36477A (da) 1977-07-31
JPS6242887B2 (es) 1987-09-10
NL179290B (nl) 1986-03-17
NO770293L (no) 1977-08-02
DE2703620A1 (de) 1977-08-04
AR214625A1 (es) 1979-07-13
JPS52102410A (en) 1977-08-27
DK146855B (da) 1984-01-23
BE850852A (fr) 1977-07-28
AT354632B (de) 1979-01-25
FR2339621B1 (es) 1980-06-06
NO145563C (no) 1982-04-21
ATA53277A (de) 1979-06-15
GB1557609A (en) 1979-12-12
DK146855C (da) 1984-07-02
FR2339621A1 (fr) 1977-08-26
MX5197E (es) 1983-04-25
NO145563B (no) 1982-01-11
DE2703620C2 (de) 1984-11-22

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