ES455985A1 - Procedimiento para preparar derivados de quinazolina. - Google Patents

Procedimiento para preparar derivados de quinazolina.

Info

Publication number
ES455985A1
ES455985A1 ES455985A ES455985A ES455985A1 ES 455985 A1 ES455985 A1 ES 455985A1 ES 455985 A ES455985 A ES 455985A ES 455985 A ES455985 A ES 455985A ES 455985 A1 ES455985 A1 ES 455985A1
Authority
ES
Spain
Prior art keywords
procedure
formula
quinazoline derivatives
group
nhr6
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES455985A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Publication of ES455985A1 publication Critical patent/ES455985A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para preparar derivados de quinazolina, de fórmula: **(Fórmula)** en la que (i) R1 es un átomo de hidrógeno o un grupo alquilo inferior; (R2)n representa de 1 a 3 sustituyentes opcionales, siendo cada R2 un átomo de hidrógeno o un grupo hidroxi o alcoxi inferior y siendo n de 1 a 3, o constituyendo dos cualquiera de las mitades R2 un grupo metilendioxi o etilendioxi unido a posiciones adyacentes del anillo A; (ii) X representa - (CH2)p-en donde p es 1 a 3; (iii) y está unido a la posición 3 ó 4 del anillo C y representa un grupo de fórmula -Z-CO-NHR6 ó -Z-CS-NHR6.
ES455985A 1974-07-25 1977-02-16 Procedimiento para preparar derivados de quinazolina. Expired ES455985A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3280574 1974-07-25

Publications (1)

Publication Number Publication Date
ES455985A1 true ES455985A1 (es) 1978-06-16

Family

ID=10344259

Family Applications (4)

Application Number Title Priority Date Filing Date
ES439690A Expired ES439690A1 (es) 1974-07-25 1975-07-24 Procedimiento para preparar derivados de quinazolina.
ES455986A Expired ES455986A1 (es) 1974-07-25 1977-02-16 Procedimiento para preparar derivados de quinazolina.
ES455985A Expired ES455985A1 (es) 1974-07-25 1977-02-16 Procedimiento para preparar derivados de quinazolina.
ES455984A Expired ES455984A1 (es) 1974-07-25 1977-02-16 Procedimiento para preparar derivados de quinazolina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES439690A Expired ES439690A1 (es) 1974-07-25 1975-07-24 Procedimiento para preparar derivados de quinazolina.
ES455986A Expired ES455986A1 (es) 1974-07-25 1977-02-16 Procedimiento para preparar derivados de quinazolina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES455984A Expired ES455984A1 (es) 1974-07-25 1977-02-16 Procedimiento para preparar derivados de quinazolina.

Country Status (7)

Country Link
AT (1) AT344178B (es)
BE (1) BE831654A (es)
CS (1) CS192549B2 (es)
ES (4) ES439690A1 (es)
HU (1) HU174961B (es)
PL (6) PL99427B1 (es)
SU (5) SU578874A3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364865A (en) * 1992-12-30 1994-11-15 Sterling Winthrop Inc. Phenoxy- and phenoxyalkyl-piperidines as antiviral agents
US20070004763A1 (en) * 2005-06-10 2007-01-04 Nand Baindur Aminoquinoline and aminoquinazoline kinase modulators

Also Published As

Publication number Publication date
SU858563A3 (ru) 1981-08-23
SU625606A3 (ru) 1978-09-25
PL193421A1 (pl) 1978-04-24
SU613723A3 (ru) 1978-06-30
ES455986A1 (es) 1978-06-01
ES455984A1 (es) 1978-06-01
CS192549B2 (en) 1979-08-31
PL99427B1 (pl) 1978-07-31
PL103789B1 (pl) 1979-07-31
ES439690A1 (es) 1977-07-01
PL103797B1 (pl) 1979-07-31
SU634671A3 (ru) 1978-11-25
PL193422A1 (pl) 1978-06-05
AT344178B (de) 1978-07-10
PL104615B1 (pl) 1979-08-31
BE831654A (fr) 1976-01-23
HU174961B (hu) 1980-04-28
ATA525275A (de) 1977-11-15
SU578874A3 (ru) 1977-10-30
PL103791B1 (pl) 1979-07-31
PL103798B1 (pl) 1979-07-31
PL193420A1 (pl) 1978-04-24
PL193419A1 (pl) 1978-04-24
PL193423A1 (pl) 1978-04-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991007