ES456499A1 - Procedimiento para producir derivados cefalosporinicos. - Google Patents

Procedimiento para producir derivados cefalosporinicos.

Info

Publication number
ES456499A1
ES456499A1 ES456499A ES456499A ES456499A1 ES 456499 A1 ES456499 A1 ES 456499A1 ES 456499 A ES456499 A ES 456499A ES 456499 A ES456499 A ES 456499A ES 456499 A1 ES456499 A1 ES 456499A1
Authority
ES
Spain
Prior art keywords
thienylacetamido
acylamino
phenyl
compounds
cephalosporin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES456499A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2348276A external-priority patent/JPS52106888A/ja
Priority claimed from JP2348376A external-priority patent/JPS52106894A/ja
Priority claimed from JP2348576A external-priority patent/JPS52106895A/ja
Priority claimed from JP2348476A external-priority patent/JPS52106889A/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of ES456499A1 publication Critical patent/ES456499A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Los compuestos preparados según la invención presentan una notable actividad antimicrobiana contra bacterias con las que son escasamente eficaces los compuestos conocidos de la serie de la cefalosporina, tales como Pseudomonas aeruginosa, Proteus de reacción positiva al indol, Serratia, Enterobacter aerogenus y E. coli resistente a la Cephaloridine. Según ello, un objetivo de esta invención es proporcionar nuevos compuestos de cefalosporina que son útiles como agentes antimicrobianos.
ES456499A 1976-03-03 1977-03-03 Procedimiento para producir derivados cefalosporinicos. Expired ES456499A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2348276A JPS52106888A (en) 1976-03-03 1976-03-03 7-(n-acylamino-alpha-arylacetamido0-3-azidomethyl acid
JP2348376A JPS52106894A (en) 1976-03-03 1976-03-03 7-(n-acylamino-alpha-aryl or-thienylacetamido)-3-(heterocyclic-thiomethyl) acids
JP2348576A JPS52106895A (en) 1976-03-03 1976-03-03 77*nnacylaminooaaaryl orrthienylacetamido**33*heterocyclic thiomethyl* 33cephemm44carboxylic acids
JP2348476A JPS52106889A (en) 1976-03-03 1976-03-03 7-(n-acylamino-alpha-aryl or-thienylacetamido)-3-carbamoyl-3-cephem-4-carb oxylic acids

Publications (1)

Publication Number Publication Date
ES456499A1 true ES456499A1 (es) 1978-11-16

Family

ID=27457971

Family Applications (2)

Application Number Title Priority Date Filing Date
ES456499A Expired ES456499A1 (es) 1976-03-03 1977-03-03 Procedimiento para producir derivados cefalosporinicos.
ES468662A Expired ES468662A1 (es) 1976-03-03 1978-03-16 Procedimiento para producir derivados cefalosporinicos de utilidad terapeutica

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES468662A Expired ES468662A1 (es) 1976-03-03 1978-03-16 Procedimiento para producir derivados cefalosporinicos de utilidad terapeutica

Country Status (17)

Country Link
US (1) US4165373A (es)
AT (3) AT359186B (es)
AU (1) AU498968B2 (es)
BE (1) BE851983A (es)
CA (1) CA1120466A (es)
CH (1) CH621125A5 (es)
DE (1) DE2709293A1 (es)
DK (1) DK91277A (es)
ES (2) ES456499A1 (es)
FR (1) FR2342734A1 (es)
GB (1) GB1537949A (es)
HU (1) HU176615B (es)
MX (1) MX5388E (es)
NL (1) NL7702222A (es)
NO (1) NO770703L (es)
NZ (1) NZ183477A (es)
SE (1) SE433081B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH634848A5 (de) * 1976-08-17 1983-02-28 Fujisawa Pharmaceutical Co Verfahren zur herstellung neuer 7-(n-substituierter 2-phenylglycinamido)-3-substituierte-3-cephem-4-carbonsaeuren.
JPS5492991A (en) 1977-12-28 1979-07-23 Dainippon Pharmaceut Co Ltd N-acyl cephalosporin derivative and its salt
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
JPS6058239B2 (ja) * 1978-07-20 1985-12-19 山之内製薬株式会社 新規セフアロスポリン誘導体
JPS55139389A (en) * 1979-04-19 1980-10-31 Mitsui Toatsu Chem Inc Novel cephalosporin
JPS5572195A (en) * 1978-11-28 1980-05-30 Mitsui Toatsu Chem Inc Novel cephalosporin and antibacterial comprising it as active constituent
US4420477A (en) * 1979-11-30 1983-12-13 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4288590A (en) * 1980-02-14 1981-09-08 Bristol-Myers Company 7-[Dα-(4-Hydroxy-1,5-naphthyridine-3-carboxamido)-α-arylacetamido]-3-(N,N-dimethyl-aminomethylpyridinium) methyl-3-cephem-4-carboxylates
ES499978A0 (es) * 1980-03-05 1982-01-01 Sumitomo Chemical Co Procedimiento de producir compuestos cefalosporinicos anti- microbianos
CA1152489A (en) * 1980-03-05 1983-08-23 Takao Okuda ANTIMICROBIAL 7- (.alpha.-ACYLAMINO-.alpha.-ARYLACETAMIDO)-3- (SUBSTITUTED METHYL) CEPHALOSPORIN COMPOUNDS, THEIR COMPOSITIONS AND PRODUCTION THEREOF
JPS56158791A (en) * 1980-05-10 1981-12-07 Taisho Pharmaceut Co Ltd Cephalosporin compound
JP2004538265A (ja) * 2001-04-19 2004-12-24 ビオフェルマ ムルシア，エス．アー． α−ケト酸誘導体を使用して３−セファロスポラン酸誘導体を製造する方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5747672B2 (es) * 1973-10-13 1982-10-12
JPS5119765A (en) * 1974-08-09 1976-02-17 Takeda Chemical Industries Ltd Aminochiazoorujudotaino seizoho
JPS51115491A (en) * 1975-04-03 1976-10-12 Sumitomo Chem Co Ltd Method for preparing 77* *44hydroxyy1*5 naphthyridinee33carboxyamino ** phenylacetamido*cephalosporins
US4045438A (en) * 1975-10-24 1977-08-30 Yeda Research And Development Co. Ltd. Cephalosporin antibiotics
US4025626A (en) * 1975-12-09 1977-05-24 Smithkline Corporation 7-Acyl-3-(ureidoalkyl substituted tetrazolylthiomethyl)-cephalosporins

Also Published As

Publication number Publication date
SE433081B (sv) 1984-05-07
SE7702332L (sv) 1977-09-04
FR2342734A1 (fr) 1977-09-30
DK91277A (da) 1977-09-04
AT359194B (de) 1980-10-27
GB1537949A (en) 1979-01-10
DE2709293A1 (de) 1977-09-08
HU176615B (en) 1981-03-28
ES468662A1 (es) 1979-11-01
ATA198679A (de) 1980-03-15
NL7702222A (nl) 1977-09-06
AU2281377A (en) 1978-09-07
AU498968B2 (en) 1979-03-29
MX5388E (es) 1983-07-07
CH621125A5 (es) 1981-01-15
CA1120466A (en) 1982-03-23
AT359186B (de) 1980-10-27
NZ183477A (en) 1979-06-19
US4165373A (en) 1979-08-21
AT359193B (de) 1980-10-27
ATA198779A (de) 1980-03-15
ATA140077A (de) 1980-03-15
FR2342734B1 (es) 1981-06-19
BE851983A (fr) 1977-07-01
NO770703L (no) 1977-09-06

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