ES457244A1 - Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. - Google Patents

Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina.

Info

Publication number
ES457244A1
ES457244A1 ES457244A ES457244A ES457244A1 ES 457244 A1 ES457244 A1 ES 457244A1 ES 457244 A ES457244 A ES 457244A ES 457244 A ES457244 A ES 457244A ES 457244 A1 ES457244 A1 ES 457244A1
Authority
ES
Spain
Prior art keywords
ethanolamine
chlorophenoxy
prepn
ethyl nicotinate
hypolipaemic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457244A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Publication of ES457244A1 publication Critical patent/ES457244A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)

Abstract

Un procedimiento de preparación del clorhidrato de N-nicotinoil-O-p-cloro-fenoxi-isobutanoil-etanol-amina de fórmula *** ver imagen 01 caracterizado porque se aminoliza nicotinato de etilo por etanol-amina y porque se trata in situ la N-(hidroxi-2-etil)-nicotinamida por cloruro de p-cloro-fenoxi-isobutiroilo.
ES457244A 1976-03-29 1977-03-26 Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina. Expired ES457244A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7609253A FR2346010A2 (fr) 1976-03-29 1976-03-29 Procede de preparation du chlorhydrate de n-nicotinoyl o-p-chloro phenoxy isobutanoyl ethanol amine, utile dans le traitement des dislipidemies et la prevention de l'atherosclerose

Publications (1)

Publication Number Publication Date
ES457244A1 true ES457244A1 (es) 1978-02-01

Family

ID=9171169

Family Applications (1)

Application Number Title Priority Date Filing Date
ES457244A Expired ES457244A1 (es) 1976-03-29 1977-03-26 Un procedimiento de preparacion del clorhidrato de n-nicoti-noil-3-p-cloro-fenoxi-isobutanoil-etanol-amina.

Country Status (4)

Country Link
CA (1) CA1095051A (es)
ES (1) ES457244A1 (es)
FR (1) FR2346010A2 (es)
ZA (1) ZA771892B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619938A (en) * 1984-03-21 1986-10-28 Terumo Kabushiki Kaisha Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors

Also Published As

Publication number Publication date
CA1095051A (fr) 1981-02-03
FR2346010B2 (es) 1979-05-18
ZA771892B (en) 1978-03-29
FR2346010A2 (fr) 1977-10-28

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