ES457496A1 - Procedimiento para la obtencion de una composicion pulveru- lenta e hidrosoluble de sulfamidina y pirimetamina. - Google Patents

Procedimiento para la obtencion de una composicion pulveru- lenta e hidrosoluble de sulfamidina y pirimetamina.

Info

Publication number
ES457496A1
ES457496A1 ES457496A ES457496A ES457496A1 ES 457496 A1 ES457496 A1 ES 457496A1 ES 457496 A ES457496 A ES 457496A ES 457496 A ES457496 A ES 457496A ES 457496 A1 ES457496 A1 ES 457496A1
Authority
ES
Spain
Prior art keywords
water
sulfadimidine
pyrimethamine
soluble composition
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457496A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abic Ltd
Original Assignee
Abic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abic Ltd filed Critical Abic Ltd
Publication of ES457496A1 publication Critical patent/ES457496A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Procedimiento para la obtención de una composición pulverulenta e hidrosoluble de sulfadimidina y pirimetamina, caracterizado por el hecho de hacer reaccionar N-(4,6-dimetil-2-pirimidinil)-sulfanilamida con ácido sulfúrico, adicionado luego polivinilpirrolidia y una sal hidroluble y fisiológicamente aceptable, de 2,4-diamino-5-(p-clorofenil-6-etil)-pirimidina al sulfato de sulfadimidina obtenido.
ES457496A 1976-04-14 1977-04-04 Procedimiento para la obtencion de una composicion pulveru- lenta e hidrosoluble de sulfamidina y pirimetamina. Expired ES457496A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL49412A IL49412A (en) 1976-04-14 1976-04-14 Water-soluble composition comprising sulfadimidine and pyrimethamine

Publications (1)

Publication Number Publication Date
ES457496A1 true ES457496A1 (es) 1978-03-16

Family

ID=11048813

Family Applications (1)

Application Number Title Priority Date Filing Date
ES457496A Expired ES457496A1 (es) 1976-04-14 1977-04-04 Procedimiento para la obtencion de una composicion pulveru- lenta e hidrosoluble de sulfamidina y pirimetamina.

Country Status (11)

Country Link
US (1) US4062940A (es)
JP (1) JPS52125632A (es)
BE (1) BE853495A (es)
CA (1) CA1063514A (es)
DE (1) DE2712198A1 (es)
ES (1) ES457496A1 (es)
FR (1) FR2347929A1 (es)
GB (1) GB1521648A (es)
IL (1) IL49412A (es)
NL (1) NL7703914A (es)
ZA (1) ZA772227B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009559B1 (de) * 1978-08-01 1982-08-25 Ciba-Geigy Ag Stabile flüssige Arzneimittelformulierung, ihre Herstellung und Verwendung
EP2186521A1 (en) * 2008-11-14 2010-05-19 Mergemeier Steffen Compositons for the treatment and prevention of diseases involving bacterial, viral and fungal pathogens and fragments thereof with polyvinylpyrrolidone and/or polyvinylpolypyrrolidone as therapeutically active compound
CN103709109B (zh) * 2013-12-24 2016-08-17 福建省福抗药业股份有限公司 一种磺胺二甲嘧啶硫酸氢盐的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728452A (en) * 1971-01-20 1973-04-17 Abic Ltd Water-soluble composition comprising sulfadimidine and pyrimethamine
US3985876A (en) * 1973-01-05 1976-10-12 Burroughs Wellcome Co. Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine

Also Published As

Publication number Publication date
CA1063514A (en) 1979-10-02
DE2712198A1 (de) 1977-11-03
BE853495A (fr) 1977-10-12
FR2347929B1 (es) 1980-03-21
GB1521648A (en) 1978-08-16
IL49412A (en) 1979-03-12
US4062940A (en) 1977-12-13
FR2347929A1 (fr) 1977-11-10
ZA772227B (en) 1978-03-29
NL7703914A (nl) 1977-10-18
IL49412A0 (en) 1976-06-30
JPS52125632A (en) 1977-10-21

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