ES457527A1 - Procedimiento para preparar derivados de piperacina susti- tuidos. - Google Patents

Procedimiento para preparar derivados de piperacina susti- tuidos.

Info

Publication number
ES457527A1
ES457527A1 ES457527A ES457527A ES457527A1 ES 457527 A1 ES457527 A1 ES 457527A1 ES 457527 A ES457527 A ES 457527A ES 457527 A ES457527 A ES 457527A ES 457527 A1 ES457527 A1 ES 457527A1
Authority
ES
Spain
Prior art keywords
group
procedure
derivatives
piperacine
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES457527A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES457527A1 publication Critical patent/ES457527A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/137—Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para preparar derivados de piperacina substituidas de fórmula I: *** en donde R2 es hidrógeno, alquilo inferior, hidroxi-alquilo inferior o fenilo facultativamente substituido por un grupo hidroxialquilo o alquilo inferior, Y es oxígeno o azufre, X es un grupo de fórmula C = O, C = S ó CHOH, Z es oxígeno, azufre o un enlace directo, R3 es un grupo alquilo o alquenilo de cadena lineal o ramificada, que está substituido en un grupo metilo por dos o tres átomos de halógeno, o es un grupo adamantilo, m es 0 ó 1, y n es un número entero de 0 a 4, con la condición de que cuando m=0, entonces n=0, con la condición de que cuando X es un grupo de fórmula ¿CHOH- entonces m es 0, n es 1 y Z es un enlace directo.
ES457527A 1976-04-09 1977-04-05 Procedimiento para preparar derivados de piperacina susti- tuidos. Expired ES457527A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH452976 1976-04-09
CH453076 1976-04-09

Publications (1)

Publication Number Publication Date
ES457527A1 true ES457527A1 (es) 1978-08-16

Family

ID=25695707

Family Applications (1)

Application Number Title Priority Date Filing Date
ES457527A Expired ES457527A1 (es) 1976-04-09 1977-04-05 Procedimiento para preparar derivados de piperacina susti- tuidos.

Country Status (13)

Country Link
US (1) US4112091A (es)
JP (1) JPS52125179A (es)
AU (1) AU2405177A (es)
DE (1) DE2713586A1 (es)
DK (1) DK147677A (es)
ES (1) ES457527A1 (es)
FR (1) FR2347357A1 (es)
GB (1) GB1563431A (es)
IT (1) IT1084062B (es)
LU (1) LU77079A1 (es)
NL (1) NL7703692A (es)
NZ (1) NZ183837A (es)
SE (1) SE7703736L (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU562546B2 (en) * 1981-12-02 1987-06-11 Ferrosan A.B. 1-piperazinocarboxylates, process for their preparation and pharmaceutical compositions containing them
US4959364A (en) * 1985-02-04 1990-09-25 G. D. Searle & Co. Method of treating inflammation, allergy, asthma and proliferative skin disease using heterocyclic amides
DE3600390A1 (de) * 1986-01-09 1987-07-16 Hoechst Ag Diarylalkyl-substituierte alkylamine, verfahren zu ihrer herstellung, ihre verwendung sowie sie enthaltende arzneimittel
EP0300325B1 (en) * 1987-07-20 1993-06-16 COMETEC S.r.l. Compositions for promoting growth of animals
KR890011868A (ko) * 1988-01-26 1989-08-23 원본미기재 간질환 치료제 및 피페라진 유도체
US4977156A (en) * 1988-07-26 1990-12-11 The Dow Chemical Company Amino piperazine esters showing biocidal activity
CN1157388C (zh) * 2001-05-29 2004-07-14 北京大学 哌嗪基二硫代甲酸酯类化合物,它们的制备方法和在抗肿瘤药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE577438A (es) * 1958-04-07
US3733417A (en) * 1969-12-19 1973-05-15 Smith Kline French Lab Methods and compositions for improving feed efficiency of ruminants using polyhaloalkamines
US3962246A (en) * 1973-07-25 1976-06-08 Sandoz Ltd. Bromo-propanol derivatives as flame retardants

Also Published As

Publication number Publication date
GB1563431A (en) 1980-03-26
DK147677A (da) 1977-10-10
FR2347357A1 (fr) 1977-11-04
AU2405177A (en) 1978-10-12
IT1084062B (it) 1985-05-25
LU77079A1 (es) 1977-11-17
NZ183837A (en) 1980-03-05
DE2713586A1 (de) 1977-10-20
SE7703736L (sv) 1977-10-10
NL7703692A (nl) 1977-10-11
JPS52125179A (en) 1977-10-20
US4112091A (en) 1978-09-05

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