ES459471A1 - Procedimiento para la preparacion de nuevas-9-alcohilamino- eritromicinas. - Google Patents
Procedimiento para la preparacion de nuevas-9-alcohilamino- eritromicinas.Info
- Publication number
- ES459471A1 ES459471A1 ES459471A ES459471A ES459471A1 ES 459471 A1 ES459471 A1 ES 459471A1 ES 459471 A ES459471 A ES 459471A ES 459471 A ES459471 A ES 459471A ES 459471 A1 ES459471 A1 ES 459471A1
- Authority
- ES
- Spain
- Prior art keywords
- opt
- alkyl
- gram
- branched
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940088710 antibiotic agent Drugs 0.000 title abstract 2
- 241000894006 Bacteria Species 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 229960003276 erythromycin Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 3
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000002490 anilino group Chemical group [H]N(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000000440 benzylamino group Chemical group [H]N(*)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 125000005191 hydroxyalkylamino group Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la preparación de nuevas 9-alcohilamino-eritromicinas de la fórmula general I, *** ver imagen 01 en la que E significa el grupo eritromicilo *** ver imagen 02 R1 significa un átomo de hidrógeno, un grupo alcohilo de cadena recta o ramificada con 1 a 3 átomos de carbono, un grupo alcoxialcohilo con 1 a 3 átomos de carbono en el radical alcohileno y 1 a 5 átomos de carbono en el radical alcoxi, el grupo fenilo, el grupo bencilo; R2 significa un átomo de hidrógeno, el grupo hidroxilo, un grupo alcohilo de cadena recta o ramificada con 1 a 3 átomos de carbono, el grupo fenilo; y n significa los números 0 ó 1, y de sus sales por adición de ácido con ácidos orgánicos o inorgánicos, caracterizado porque para la preparación de compuestos caracterizado porque para la preparación de compuestos de la fórmula general I, en la que n significa el número 1, se reducen azometinaldehidos de la fórmula general II, *** ver imagen 03
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752515078 DE2515078A1 (de) | 1975-04-07 | 1975-04-07 | Neue 9-alkylamino-erythromycine, ihre salze und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES459471A1 true ES459471A1 (es) | 1978-04-16 |
Family
ID=5943239
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES459470A Expired ES459470A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuvas 9-alcohilamino- eritromicinas. |
| ES459469A Expired ES459469A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas. |
| ES459473A Expired ES459473A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas. |
| ES459471A Expired ES459471A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas-9-alcohilamino- eritromicinas. |
| ES459474A Expired ES459474A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas. |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES459470A Expired ES459470A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuvas 9-alcohilamino- eritromicinas. |
| ES459469A Expired ES459469A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas. |
| ES459473A Expired ES459473A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES459474A Expired ES459474A1 (es) | 1975-04-07 | 1977-06-03 | Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas. |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE840432A (es) |
| CS (1) | CS188278B2 (es) |
| DE (1) | DE2515078A1 (es) |
| ES (5) | ES459470A1 (es) |
| PL (1) | PL105296B1 (es) |
| ZA (1) | ZA762067B (es) |
-
1975
- 1975-04-07 DE DE19752515078 patent/DE2515078A1/de not_active Withdrawn
-
1976
- 1976-04-06 PL PL1976188537A patent/PL105296B1/pl unknown
- 1976-04-06 BE BE165883A patent/BE840432A/xx unknown
- 1976-04-06 ZA ZA762067A patent/ZA762067B/xx unknown
- 1976-04-06 CS CS762266A patent/CS188278B2/cs unknown
-
1977
- 1977-06-03 ES ES459470A patent/ES459470A1/es not_active Expired
- 1977-06-03 ES ES459469A patent/ES459469A1/es not_active Expired
- 1977-06-03 ES ES459473A patent/ES459473A1/es not_active Expired
- 1977-06-03 ES ES459471A patent/ES459471A1/es not_active Expired
- 1977-06-03 ES ES459474A patent/ES459474A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2515078A1 (de) | 1976-10-28 |
| ES459474A1 (es) | 1978-04-16 |
| ES459470A1 (es) | 1978-04-16 |
| PL105296B1 (pl) | 1979-10-31 |
| CS188278B2 (en) | 1979-02-28 |
| BE840432A (fr) | 1976-10-06 |
| ZA762067B (en) | 1977-12-28 |
| ES459469A1 (es) | 1978-04-16 |
| ES459473A1 (es) | 1978-04-16 |
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